December 6, 2016 at 1:25 pm #2705
I was happy to find your site to be very very helpful! However I have some personal questions that maybe you can help me with please. Pharmacists are not familiar with herbal or nootropic supplements and my concern is combining a nootropic like prescription, at least in my opinion it is, with a herbal type nootropic.
My specific prescription of low dose naltrexone at 4 mg., which helps to modulate the immune system by reducing pain and other immune modulations and helping the body to produce more of its own met -enkephalins and endorphins and mixing with certain nootropics supplements such as Samè, Ashwaganda and Vinpocetine, specifically at the same time. I find LDN has helped significantly and is very safe for many many years. I also find that iodine has helped immensely along with colostrum and has been extraordinary as far as clearing brain tension, fog and deterioration.
After reading info from your site that some nootropics are inhibitors and others are additive to Acetylcholinesterase in the brain I am a little more aware that I should probably be more cautious I suppose. Although I am finding that ashwaganda, an inhibitor of Acetylcholinesterase along with citicoline, the opposite has helped me so far together but I wonder about longer term. I am also starting to take Samè with all the recommended and important B vitamins. I am not sure if Samè is an inhibitor or the opposite also?
I would like to add vinpocetine when I feel I need to this . Will this mix pose too many problems together in your opinion including the ldn or even without the ldn? I dont think I am ready to give up the LDN just yet though.
The vinpocetine would only be on a temporary basis for dialating blood vessels for tension/stress headaches which have been greatly although not totally diminished in the recent years.
Thanks so much for your time and concern for people. It is an admired quality. All the best. TheresaDecember 8, 2016 at 2:52 pm #2711
Hi Theresa, naltrexone is primarily an opioid receptor antagonist. Which is likely the reason why LDN helps so many people dealing with fibromyalgia. Dr. John Lowe spent much of his life researching hypothyroidism. And found that once someone’s T-3 levels were optimal, fibromyalgia symptoms were gone. You can read more about that here > http://www.thyroidscience.com/cases/lowe.9.6.10/lowe.t3.fms.9.6.10.htm
I’ve been hypothyroid for many years and have been using natural desiccated thyroid. And had nearly all the symptoms including severe brain fog and fibromyalgia. It took about 3 years, but all the pain from fibromyalgia disappeared. I believe it was because I finally got my T-3 levels up. I never tried LDN.
It looks to me like you’re doing all the right things. Particularly in taking a cautious approach to dosing and mixing supplements and meds. I can’t find any contraindications for anything related to LDN. Even using it long-term.
In my humble opinion, nearly everybody should be taking Vinpocetine. For the rest of their life. Unless they have problems with low blood pressure or problems with blood clotting. It improves cerebral blood flow, and reduces inflammation. Take a careful read of the article I wrote on Vinpocetine for more.
SAM-e also helps relieve the symptoms of fibromyalgia along with improving memory. I won’t go into detail here because you can read through the article I wrote on SAM-e. Just make sure you take it with a high-quality B-Vitamin complex that includes folate (not folic acid) and B12 methylcobalamin (not cobalamin or other inferior forms). And take it on an empty stomach. Reasons explained in the article.
I appreciate the compliment too. My motivation for this site was to show it really is possible to fix your brain using natural supplements. I did it and it saved my life. Please let me know if you have any other questions or need clarification on anything.