what is glutathione used for


David Tomen
David Tomen
13 minute read
Glutathione is a potent antioxidant, supports healthy cognition, fights oxidative stress and inflammation, and counters the effects of aging

Glutathione (γ-l-glutamyl-l-cysteinyl-glycine, GSH or L-glutathione) is a tripeptide made up of cysteine, glycine, and glutamine and present in high concentrations in every cell in your body. [i]

As an antioxidant, glutathione’s primary role is to protect your cells from free radical damage. And plays a vital role in detoxification.

Glutathione protects against chronic illness, supports liver health, and reduces insulin resistance. Some research shows that glutathione may even help prevent the progression of cancer.[ii]

The benefits of supplementing with glutathione may help prevent and even reduce the symptoms associated with emotional and mental health disorders.

Other glutathione benefits include improved digestion, clearer skin, stronger hair and nails, and healthier vison.

Glutathione is unique because it can help improve the health of nearly all cell types in your body. Including your brain, liver, eyes, skin, pancreas, or any other organ that requires support.

As a nootropic, glutathione boosts memory, clearer thinking, and helps prevent neurodegenerative disease such as Alzheimer’s disease and dementia. And boosts energy levels.

In this review we’ll focus on how Glutathione works in your brain.

Glutathione helps:

  • Antioxidant: Glutathione is called the “master” antioxidant because it’s needed by every nearly every cell to defend against free radicals. Free radicals in excess can lead to oxidative stress which causes inflammation and can damage or kill brain cells.
  • Neuroprotectant: The production of adenosine triphospate (ATP) in your mitochondria releases Reactive Oxygen Species (ROS) causing oxidative stress. Glutathione is your primary defense against ROS preventing mitochondrial dysfunction.[iii]
  • Brain optimization: Supplementing with glutathione may help reduce brain fog and poor cognition. Glutathione plays a role in preventing and treating neurodegenerative disease, including Alzheimer’s disease, bipolar disorder, obsessive compulsive disorder (OCD) and autism.[iv] [v]


Glutathione (γ-l-glutamyl-l-cysteinyl-glycine, GSH, or L-glutathione) is found in nearly every cell in your brain and body.

GlutathioneGlutathione synthesis in your brain follows the same pathway as in the rest of your body. Glutathione is synthesized in cells by the consecutive reactions of the enzymes γ-Glutamyl-cysteine (γGlu-Cys) synthetase which uses glutamate and cysteine as substrates to generate γGlu-Cys.

This dipeptide is combined with glycine to glutathione in a reaction catalyzed by Glutathione synthetase. ATP is a co-substrate for both enzymes.

The intracellular level of Glutathione is regulated by a feedback inhibition of γGlu-Cys synthetase by the endproduct Glutathione.

Glutathione synthesis is dependent on the availability of glutamate, cysteine, and glycine.

You can increase your body’s glutathione production by eating foods that contain the basic components of these amino acids.

You can get Glutathione from eating onions, garlic, spinach, avocado, asparagus, cruciferous vegetables like broccoli and cauliflower, and meats.

But your digestive tract doesn’t absorb glutathione well. It is rapidly oxidized during digestion. Fortunately, many of the same foods that contain glutathione also contain the individual amino acids that your body uses to make glutathione.

These foods include eggs, lentils, chicken, fish, dairy products, legumes, garlic, shallots, and onions. And cruciferous vegetables such as broccoli, cauliflower, cabbage, kale, Bok choy, and Brussels sprouts.

Glutathione is so critical to your cellular health that it exists in cells at the same levels as glucose, potassium, and cholesterol. All nutrients that are essential for energy and cellular function.[vi]

As your “master” antioxidant, Glutathione plays a key role in the defense of brain cells against oxidative stress. It neutralizes free radicals, is a cofactor for several antioxidant enzymes, and helps regenerate Vitamin C and Vitamin E already in your system.

Glutathione assists in the transport of heavy metal ions such as mercury out of cells including your brain. It helps regulate cellular growth and apoptosis. And it vital to mitochondrial function and maintenance of mitochondrial DNA.

Your body requires a steady supply of glutathione to function optimally. Glutathione deficiency has been associated with neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Huntington’s, OCD and even autism.[vii]

Glutathione increases the number of T-cells (white blood cells) in your body, a key component of your immune system. And stimulates the production and activity of natural killer (NK) cells and supports immune cell normal antibody response.[viii]

In fact, glutathione deficiency, and its precursor cysteine, is a feature of HIV. One study showed that supplementing with N-acetyl-L-cysteine (NAC), a precursor to glutathione, caused a significant increase in immune response in HIV-infected patients.[ix]

Your body naturally produces glutathione, but that ability decreases with age. And decreases at any age when you’re under stress.

liposomal glutathioneHow does Glutathione work in the Brain?

Glutathione boosts brain health and function in several ways. But two in particular stand out.

  1. Glutathione protects brain mitochondria from oxidative stress. Glutathione is the number one antioxidant in your body. As an antioxidant, it neutralizes and scavenges free radicals, protecting your mitochondria from oxidative damage.[x]

Free radicals are molecules with unpaired electrons. Free radicals increase because of various toxins, industrial chemicals, air pollutants, UV light, certain drugs, and pesticides.[xi]

Free radicals in excess pair with other free electrons in cells resulting in decreased cellular function and disease.

Antioxidants such as glutathione attach to free electrons preventing them from causing oxidative stress.[xii]

In your brain, neurons rely on the presence of extracellular cysteine for glutathione synthesis. The best extracellular precursor for glutathione synthesis in your brain is glutamine.

But astrocytes prefer glutamate and cysteine as precursors. In fact, astrocytes play a key role in glutathione metabolism in your brain.[xiii]

  1. Glutathione helps recycle other antioxidants.

When your brain uses antioxidants such as Vitamin C and Vitamin E, glutathione recycles these important antioxidants and put them back to into play.[xiv] [xv] Enhancing the efficiency of the detoxification process, helping your brain to function optimally.

When your brain has enough glutathione, you can potentially avoid anxiety, depression, and more serious neurodegenerative diseases such as Alzheimer’s, Huntington’s, and Parkinson’s disease.[xvi]

How things go bad

Glutathione exists in cells in 2 states: reduced Glutathione (GSH) and oxidized Glutathione (GSSG). Oxidized glutathione is 2 glutathione molecules bound together.

glutathione benefitsThe ratio of GSH to GSSG determines cell redox status. Healthy cells at rest have a GSH/GSSG ratio >100 while the ratio drops to 1 to 10 in cells exposed to oxidative stress.

Glutathione is depleted because of oxidative stress, inflammation, or exposure to toxins within the cell.[xvii]

Without enough glutathione, your body is more susceptible to a host of cognition problems. And if left unchecked can eventually lead to neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and dementia.

Glutathione deficiency can also affect your vision, skin health, and ability to think clearly.

Insufficient levels of glutathione can lead to:

↓ Neurodegenerative disease, including Alzheimer’s diseases and Parkinson’s disease

↓ Brain fog

↓ Low energy

↓ Poor digestion

↓ Vision problems

↓ Decreased emotional and mental health[xviii]

↓ Inefficient detoxification of your cells

↑ Greater susceptibility to diabetes, heart disease, and cancer

↑ Increased free radical damage to cells

↑ Inflammatory diseases

You become more susceptible to these problems as you age because your body’s ability to produce glutathione decreases.

Common OTC medications such as acetaminophen (Tylenol®) has been shown to deplete glutathione, especially in your liver. This means that when using acetaminophen, it makes it harder for your body’s immune system to do its job of cleaning out waste products.

But taking Glutathione as a nootropic supplement may help counter the damage caused by oxidative stress when you have no choice but to take an acetaminophen tablet.

glutathione side effectsGlutathione benefits

It would be difficult to understate the benefits of having sufficient levels of glutathione in your body. It helps your body detox. And is vital to protecting your cells from free radical damage.

Your brain uses at least 20% of your oxygen supply to function which makes it highly susceptible to oxidative stress. Healthy levels of glutathione helps prevent oxidative stress.  And allows your brain to function as designed.

Supplementing with glutathione helps prevent anxiety and depression. Adequate glutathione supports healthy, clear cognition. And helps protect your brain against neurodegenerative diseases as you age.

But glutathione’s benefits aren’t limited to your brain. It plays a protective role in nearly every cell in your body. Protecting you from a variety of degenerative and inflammatory diseases.

How does Glutathione feel?

Neurohackers who supplement with Glutathione report increased energy levels, improved digestion, decreased inflammation, clearer thinking, improved skin tone, and stronger hair and nails.

what is glutathione used forAs your master antioxidant, glutathione boosts cellular health throughout your system.

People who suffer with Hashimoto’s disease, diabetes, and chronic fatigue syndrome report more energy when using glutathione.

Glutathione can improve digestion, including the symptoms of leaky gut syndrome. And may also ease allergy symptoms.

With the established link between gut health and brain health, it comes as no surprise that many users of glutathione report clearer thinking.

Supplementing with glutathione help you detox, providing clear skin. Many people report that it makes their skin glow. You may find that your hair and nails grow stronger when supplementing with glutathione.

Some say they notice improvement in their hearing, a better sense of smell, and better vision after taking glutathione. It can also help prevent cataracts.[xix] Some people report that glutathione has helped them heal cataracts.

Many people report that glutathione is their best hangover prevention weapon. They say that if they remember to take it on a night when they’ve been drinking too much, they feel little to no effect the next morning.

how to increase glutathioneGlutathione Clinical Research

With such a widespread detoxifying role throughout your body, glutathione has been shown to positively affect many organs and systems. Here we focus on three that affect cognitive function.

Glutathione for OCD

Several studies suggest lower cerebral levels of glutathione may contribute to obsessive-compulsive disorder (OCD).

Researchers at Harvard Medical School and McLean Hospital in Belmont Massachusetts recruited 29 patients suffering from OCD and 25 matching controls who didn’t have OCD.

The participants brains were scanned using magnetic resonance spectroscopy (MRS) to examine glutathione levels in their posterior cingulate cortex (PCC).

The study found significantly lower glutathione levels in those with OCD compared with the control group.

The research team concluded that lower glutathione levels increased oxidative stress and hypermetabolism in the PCC brain region with OCD. [xx]

Glutathione for Alzheimer’s Disease

A study published in Neuropharmacology studied the effect of glutathione supplementation in mice with biological indicators like those of Alzheimer’s.

Mice were supplemented with glutathione for three weeks. The mice treated with glutathione showed decreased inflammation. And had reduced cognitive decline and less depression and anxiety.

The researchers concluded that glutathione supplementation is attractive as a therapy for reducing oxidative stress and inflammation in the brains of people with Alzheimer’s.[xxi]

Glutathione to Reduce Hangovers

Animal trials have shown that supplementing with glutathione may be useful in preventing hangovers.

In one study, rats in the experimental group were fed a preparation of glutathione-enriched yeast and rice embryo/soybean (GEY/RES) extracts for two weeks. Control rats were not given the GEY/RES.

The rats in both groups were then intoxicated with ethanol and blood alcohol levels were analyzed for several hours.

The rats in the pretreatment group had lower blood concentrations of alcohol. The researchers concluded that glutathione should be studied as a candidate for mitigating hangovers.[xxii]

Glutathione Recommended Dosage

glutathione supplementsRecommended nootropic dosage for Reduced or Liposomal Glutathione for immune support is 250 – 1,000 mg per day.

Glutathione is not well-absorbed in your digestive system, so the liposomal form of glutathione is preferred.

You can also increase your glutathione levels by supplementing with one of my favorite supplements – N-Acetyl-L-Cysteine (NAC) which is a direct precursor to glutathione.

NAC is easily digested and goes on to help produce glutathione in your liver. Recommended nootropic dosage of NAC is 600 3-times per day.[xxiii] [xxiv]

Glutathione Side Effects

Glutathione is non-toxic. So is considered well-tolerated and safe.

Side effects are rare but can include digestive cramping and bloating, and possible skin rash if you apply glutathione to your skin.

If you have asthma, you should avoid supplementing with glutathione.

And if you are pregnant or breastfeeding, please check with your doctor before beginning glutathione supplementation.

Type of Glutathione to Buy

Glutathione supplements are available in tablet, softgel, capsule, powder, liquid, nasal spray and IV form. Capsules are typically 350 – 500 mg each.

Glutathione exists in cells in 2 states: reduced Glutathione (GSH) and oxidized Glutathione (GSSG).

If you are buying regular glutathione, choose a supplement label that says “Reduced Glutathione” which is the active form your immune system needs. And NOT the oxidized form of “Glutathione”.

Early human clinical trials of supplemental glutathione showed it was not absorbed well as a supplement. And for years it was thought that using GSH precursors were a superior method of increasing stores of this vital antioxidant in your body. But the latest research shows with daily, long-term usage you can raise glutathione levels by supplementing with glutathione.

The best way to increase your glutathione levels is by IV infusion. But this method is expensive and not easily available to the average neurohacker.

So, supplement manufacturers have found another method for boosting glutathione absorption.

It is called “liposomal” which means glutathione is encased in a “sac” of lipid molecules made from soy or sunflower lecithin which makes it easier for the molecule to cross cell membranes into the cell.

A patented form of liposomal glutathione called Setria® Glutathione manufactured by Kyowa Hakko Bio Co. has been shown to be the quickest way to increase your glutathione levels.

A 6-month randomized, double-blind, placebo-controlled trial of Setria® glutathione (GSH) 250 or 1,000 mg per day was conducted with 54 adults.

Blood levels of GSH increased after 1, 3, and 6 months at both doses. At 6 months the low dose group showed 29% GSH levels and the high dose group 35%.[xxv]

Performance Lab - PL-ImmuneYou can get 250 mg Setria® Glutathione in my favorite immune supplement called Performance Lab® PL-Immune™.

PL-Immune™ also contains the NutriGenesis® forms of Vitamin D 20 mcg, Vitamin C 30 mg, Selenium 25 mcg, Zinc 5 mg, and IMMUSE™ Paraprobiotic.

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7 clinical trials have shown that pDC can activate immune cells such as NK, Killer-T, Helper-T, and B cells, providing broad range immune support.

Performance Lab® PL-Immune™ is only $34 for a one-month supply of the best immune supplement available today. Get 3 boxes and Get one box FREE + free shipping.

Nootropics Expert® Recommendation

Nootropics Expert Tested and ApprovedGlutathione 250 – 1,000 mg per day

I recommend glutathione as a nootropic supplement.

Glutathione’s role in immune function is almost unparalleled. Nearly all cells require GSH for healthy function.

Your body makes glutathione on its own, but that ability diminishes when you are experiencing severe stress, a poor diet, and as you get older.

Supplementing with glutathione protects against chronic illness, supports liver health, and reduces insulin resistance. Some research shows that glutathione may even help prevent the progression of cancer. [xxvi]

Glutathione is especially helpful for those dealing with brain fog, poor memory, anxiety, or depression. You should notice better memory, more energy, and the ability to think more clearly when using GSH as a supplement.

Because glutathione supports healthy brain cell function, it may help reduce symptoms of OCD, depression, bipolar disorder, and autism.

Glutathione may help prevent or slow age-related cognitive decline, such as in dementia or Alzheimer’s disease.

And supplementing with glutathione may help vison, poor digestion, unhealthy skin and brittle hair and nails.

The preferred method of supplementing with glutathione is with the patented liposomal form of glutathione such as Setria® Glutathione available in Performance Lab® PL-Immune™.

As an Amazon Associate I earn from qualifying purchases. This post may also contain other affiliate links and I will be compensated if you make a purchase after clicking on my links.

[i] Bjørklund, G., Doşa, M. D., Maes, M., Dadar, M., Frye, R. E., Peana, M., & Chirumbolo, S. (2021). The impact of glutathione metabolism in autism spectrum disorder. Pharmacological research, 166, 105437. (source)

[ii] Traverso, N., Ricciarelli, R., Nitti, M., Marengo, B., Furfaro, A. L., Pronzato, M. A., Marinari, U. M., & Domenicotti, C. (2013). Role of glutathione in cancer progression and chemoresistance. Oxidative medicine and cellular longevity, 2013, 972913. (source)

[iii] Marí, M., Morales, A., Colell, A., García-Ruiz, C., & Fernández-Checa, J. C. (2009). Mitochondrial glutathione, a key survival antioxidant. Antioxidants & redox signaling, 11(11), 2685–2700. (source)

[iv] Dwivedi, D., Megha, K., Mishra, R., Mandal, P. (2020) Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Therapeutic Role in Brain Disorders. Neurochemical Research, 45, 1461–1480. (source)

[v] Cui, J., Shao, L., Young, L. T., & Wang, J. F. (2007). Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate. Neuroscience144(4), 1447–1453. (source)

[vi] Pizzorno J. (2014). Glutathione! Integrative medicine (Encinitas, Calif.)13(1), 8–12. (source)

[vii] Wu, G., Fang, Y. Z., Yang, S., Lupton, J. R., & Turner, N. D. (2004). Glutathione metabolism and its implications for health. The Journal of nutrition 134(3), 489–492. (source)

[viii] Knight J. A. (2000). Review: Free radicals, antioxidants, and the immune system. Annals of clinical and laboratory science30(2), 145–158. (source)

[ix] Dröge, W., & Breitkreutz, R. (2000). Glutathione and immune function. The Proceedings of the Nutrition Society 59(4), 595–600. (source)

[x] Song, J., Kang, S. M., Lee, W. T., Park, K. A., Lee, K. M., & Lee, J. E. (2014). Glutathione protects brain endothelial cells from hydrogen peroxide-induced oxidative stress by increasing nrf2 expression. Experimental neurobiology, 23(1), 93–103. (source)

[xi] Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals, antioxidants, and functional foods: Impact on human health. Pharmacognosy reviews4(8), 118–126. (source)

[xii] Marí, M., Morales, A., Colell, A., García-Ruiz, C., & Fernández-Checa, J. C. (2009). Mitochondrial glutathione, a key survival antioxidant. Antioxidants & redox signaling 11(11), 2685–2700. (source)

[xiii] Dringen, R., & Hirrlinger, J. (2003). Glutathione pathways in the brain. Biological chemistry384(4), 505–516. (source)

[xiv] Forman, H. J., Zhang, H., & Rinna, A. (2009). Glutathione: overview of its protective roles, measurement, and biosynthesis. Molecular aspects of medicine30(1-2), 1–12. (source)

[xv] Pizzorno J. (2014). Glutathione! Integrative medicine (Encinitas, Calif.)13(1), 8–12. (source)

[xvi] Salim S. (2017). Oxidative Stress and the Central Nervous System. The Journal of pharmacology and experimental therapeutics360(1), 201–205. (source)

[xvii] Biswas, S. K., & Rahman, I. (2009). “Environmental toxicity, redox signaling and lung inflammation: the role of glutathione.” Molecular aspects of medicine30(1-2), 60–76. (source)

[xviii] Salim S. (2017). Oxidative Stress and the Central Nervous System. The Journal of pharmacology and experimental therapeutics 360(1), 201–205. (source)

[xix] Giblin F. J. (2000). Glutathione: a vital lens antioxidant. Journal of ocular pharmacology and therapeutics: the official journal of the Association for Ocular Pharmacology and Therapeutics, 16(2), 121–135. (source)

[xx] Brennan, B. P., Jensen, J. E., Perriello, C., Pope, H. G., Jr, Jenike, M. A., Hudson, J. I., Rauch, S. L., & Kaufman, M. J. (2016). Lower posterior cingulate cortex glutathione levels in obsessive-compulsive disorder. Biological psychiatry. Cognitive neuroscience and neuroimaging1(2), 116–124. (source)

[xxi] Izumi, H., Sato, K., Kojima, K., Saito, T., Saido, T. C., & Fukunaga, K. (2020). Oral glutathione administration inhibits the oxidative stress and the inflammatory responses in AppNL-G-F/NL-G-F knock-in mice. Neuropharmacology168, 108026. (source)

[xxii] Lee, H. S., Song, J., Kim, T. M., Joo, S. S., Park, D., Jeon, J. H., Shin, S., Park, H. K., Lee, W. K., Ly, S. Y., Kim, M. R., Lee, D. I., & Kim, Y. B. (2009). Effects of a preparation of combined glutathione-enriched yeast and rice embryo/soybean extracts on ethanol hangover. Journal of medicinal food, 12(6), 1359–1367. (source)

[xxiii] Dodd, S., Dean, O., Copolov, D. L., Malhi, G. S., & Berk, M. (2008). N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility. Expert opinion on biological therapy8(12), 1955–1962. (source)

[xxiv] Borgström, L., Kågedal, B., & Paulsen, O. (1986). Pharmacokinetics of N-acetylcysteine in man. European journal of clinical pharmacology31(2), 217–222. (source)

[xxv] Richie, J.P., Nichenametla, S., Neidig, W. et al. “Randomized controlled trial of oral glutathione supplementation on body stores of glutathione.” European Journal of Nutrition 54, 251–263 (2015) (source)

[xxvi] Traverso, N., Ricciarelli, R., Nitti, M., Marengo, B., Furfaro, A. L., Pronzato, M. A., Marinari, U. M., & Domenicotti, C. (2013). Role of glutathione in cancer progression and chemoresistance. Oxidative medicine and cellular longevity2013, 972913. (source)

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Join The Discussion - 40 comments

October 6, 2023

Since you don’t recommend glutathione for people with asthma, then would you not recommend glutathione for people with emphysema?

    David Tomen
    October 8, 2023

    Jennifer, not without the direct supervision of your doctor because of possible bronchoconstriction caused by glutathione. My area of expertise is the human brain and NOT lungs. And this is complicated. This is the study I am referring to which explains what may happen: https://www.atsjournals.org/doi/10.1164/ajrccm.156.2.9611001

August 4, 2023

Hello, I have tried all forms of glutathione including the s-actyl version, liposomal, and now regular reduced glutathione. I like the energy and mood boost it gives me but I noticed I get VERY bloated and gassy every time. The least offensive version is the regular glutathione. But I was wondering if it ever gets better? I take it on an empty stomach in the morning. It’s so bad it effects my appetite and I am considering giving it up.

    David Tomen
    August 4, 2023

    Try using NAC instead which boosts Glutathione naturally in your system. And see if you get the same reaction.

Ryan Smith
March 22, 2023

I read for your body to absorb this it needs to be Liposomal glutathione. What are your thoughts on this

    David Tomen
    March 22, 2023

    Ryan, it is not liposomal glutathione but “reduced glutathione” for your body to use it.

      Ryan Smith
      March 23, 2023

      Thank you for the answer
      I have trouble with insomnia, have you ever heard of Glutathione interrupting sleep?

        David Tomen
        March 28, 2023

        Ryan, it is the opposite. Studies have shown that those with higher glutathione levels get better sleep.

        christopher woodard
        May 16, 2023

        I can confirm the sleeping well aspect. I’ve been taking Glycine with NAC (two of the three precursors. Glutamine being the third) and I’ve slept much better since taking it. I’ve also noticed better cognitive performance. It’s been great so far.

      Ryan Smith
      March 27, 2023

      Thanks for the clarification.
      I have read were it may be better to use NAC to help increase your glutathione instead of taking it directly.
      Should I try NAC first?

        Ryan Smith
        March 27, 2023

        Sorry one more question, what are your thought on this Double Wood glutathione? It does not say if it is “reduced”
        Thank you
        Double Wood Liposomal Glutathione

        David Tomen
        March 31, 2023

        Ryan, that is a “reduced” form and it is liposomal glutathione which has been shown to be more easily absorbed compared to regular “reduced” glutathione.

        David Tomen
        March 31, 2023

        Ryan, that is what I thought at first. But when I was researching Glutathione I found that our brain uses both forms. Some regions prefer NAC and some prefer glutathione. So ideally it is helpful to use both forms.

David N.
March 8, 2023

Outstanding article on Glutathione. I’m very much appreciative for all the work you do, and especially am grateful for learning about a few excellent supplements thru your recommendations! Ones that I probably badly need.

I have a question about the PL-Immune product, which has 250 mg Glutathione per pill. If I choose to take 2 pills per day, to obtain 500 mg of GSH per day total, would it be best to take them “both at once” (all in one setting), or “separately” (twice but at different times of the day) for optimum health benefits? For most people, do you think 2 pills a day is OK?

February 20, 2023

I was told at one time that if you take liposomal glutathione, you should always take a binder with it, like charcoal. Is this true?

    David Tomen
    February 21, 2023

    Kanna, No, No and No. Just make sure that the “liposomal” Glutathione supplement label says “Reduced Glutathione” which is the active form your immune system needs. And NOT the oxidized form of “Glutathione”.

July 14, 2022

Hello David. I read about the effects that glutathione has as a nootropoic. I feel the same effects when I take milk thistle. Can I attriute these effects to milk thistle. Kindly, let me know.

    David Tomen
    July 15, 2022

    Jawad, both Glutathione and Milk Thistle act as antioxidants. Glutathione is used throughout your body and brain. But Milk Thistle is use primarily for liver health.

February 21, 2022

Hi David how are you?,
I just wanted to know if this brand a good choice for L-Glutathione? (has no other ingredients)

Bulk Supplements Glutathione Reduced Powder

    David Tomen
    February 21, 2022

    Martin, Bulk Supplements is a good company and has a robust testing program in place. That is likely a good supplement. I suggest spending some time reading the User Reviews for an objective opinion on its value as a supplement.

February 10, 2022

Hi David! Can I take 500mg Glutathione and 1800mg NAC per day? Does it make any sense? I’m very prone to runny nose which drives me crazy!

    David Tomen
    February 11, 2022

    Adam, try it because your brain uses both NAC and Glutathione.

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