Table of Contents
Key Takeaways
- Serotonin modulation through nootropics like L-Tryptophan, 5-HTP, Bacopa Monnieri, Ginkgo Biloba, and Rhodiola Rosea can provide relief from social anxiety symptoms.
- GABA, the main inhibitory neurotransmitter, can be increased for anxiety relief, with nootropics like Aniracetam and Oxiracetam affecting GABA transmission.
- Dopamine signaling, enhanced by nootropics like L-Tyrosine and L-Theanine, promotes self-confidence and may reduce social anxiety.
- Modulating norepinephrine using nootropics like Magnesium and St. John’s Wort can aid in managing social anxiety symptoms.
- Glutamate modulating nootropics like Cat’s Claw, Racetams, and Noopept may help in unlearning social anxiety triggers, similar to Cognitive Behavior Therapy approaches.
If you feel inadequate, embarrassed, inferior or humiliated. And it prevents you from going out, meeting new people, or generally messes with your your mental energy and quality of life – nootropics can help.
Social anxiety is form of anxiety. And affects at least 13% of people living in the U.S.[i] But a very recent survey conducted in the USA revealed that nearly half of those surveyed said they were suffering with some form of anxiety.
You are dealing with social anxiety if you tend to avoid going into any situation where you feel you may be negatively judged or evaluated. Back in the day, they used to call these things ‘phobias’. In this case, it was “social phobia”.
Social anxiety is treated by mainstream medicine in two ways – Cognitive Behavior Therapy or with drugs. You may have tried either or both with limited success.
In this post, you’ll find out why drugs often do not succeed in taming your symptoms. Here you’ll learn about some natural options that may work better.
What Causes Social Anxiety
One of the problems with social anxiety is poor self-esteem. It always feels like it’s somehow your fault. You may feel that social anxiety is a moral failure. Or could have been caused by a crappy childhood.
Nothing could be further from the truth. Social anxiety is sometimes caused by a neurotransmitter imbalance in your brain. And if this balance of neurotransmitters and their systems is restored, you may get relief from your social anxiety symptoms.
Social anxiety symptoms may be a Neurotransmitter Problem
Your brain is governed by multiple neurotransmitter systems. The most extensive of these are GABA (gamma-aminobutyric acid) and glutamate.
The other three neurotransmitter systems – serotonin, dopamine and norepinephrine – have also been studied extensively in both normal states, states of anxiety, and chronic stress.[ii]
And we know that each of these neurotransmitters are often associated with generalized anxiety disorder because there are prescription drug therapies that affect each one.
But social anxiety is not likely caused by a deficiency in one particular neurotransmitter or another. The networks governed by these neurotransmitters are interrelated, have multiple feedback loops, and sport complex receptor structures.[iii]
This is why you may have had little success with reducing your anxiety if you have tried using prescription benzos, SSRIs or MAOIs. Because they did not directly correct the cause of your anxiety.
Next, we’ll take a look at each neurotransmitter system and examine how something other than serotonin, GABA, or glutamate may be causing your problem. You will learn how to test this idea safely and hopefully reduce your anxiety levels naturally.
Serotonin
Serotonin plays a fundamental role in regulating your brain states. Including anxiety. Serotonin also modulates dopamine and norepinephrine in your brain.[iv]
To complicate things even further, you have several different serotonin receptor subtypes. For example, the serotonin-1a receptor is both a mediator and inhibitor of serotonin depending on whether it is on the presynaptic or postsynaptic neuron.[v]
So, not all serotonin receptor subtypes are involved with social anxiety disorder. A classic example of this is the serotonin-2a receptor which provides the psychedelic effects when you use LSD or mescaline.[vi]
But despite all this complexity, it’s true that many people get some relief from social anxiety symptoms by using meds that inhibit the reuptake of serotonin by using SSRI’s. But many do NOT respond well to SSRIs and get no relief from social anxiety symptoms or reducing stress.
If you respond well to SSRI’s but hate the side effects. And are looking for a safe alternative. You can try increasing serotonin by using nootropics like L-Tryptophan or 5-HTP.
But keep in mind that excess serotonin can be the cause of your social anxiety. So you’ll want to avoid increasing serotonin too much or avoid them altogether. You’ll know it could be excess serotonin because your anxiety gets worse if you use L-Tryptophan or 5-HTP.
Instead, you can try nootropics that help modulate serotonin and bring it under control. You can modulate serotonin by using Bacopa Monnieri, Ginkgo Biloba, Rhodiola Rosea, or Vitamin D3 with Omega-3s. All have been shown in clinical studies as well as practical user experience to reduce anxiety by keeping serotonin under control.
GABA (Gamma-aminobutyric Acid)
GABA is your main inhibitory neurotransmitter. Increases in GABA by using barbiturates or benzodiazepines can have a anxiolytic effect for some people.
Drugs in this class do not directly bind to GABA receptors. Instead, they affect the associated chloride channel. Barbiturates do this by increasing the duration of the channel’s open state. While benzodiazepines increase the frequency of opening.
The big problem with these types of drugs however is tolerance and potentially fatal side effects. And they kill your ability to encode memories.[vii]
So sometimes anticonvulsant drugs like gabapentin are used instead. Which works by blocking calcium channels. Resulting in a boost of GABA transmission.[viii]
This is why some of the racetams display anxiolytic activity. Because nootropics like Aniracetam and Oxiracetam affect calcium ion channels. Somehow increasing the excitability of those neurons and increasing the effectiveness of some neurotransmitters. More on that in the next section.
Dopamine
Dopamine’s role in optimal cognition as well as anxiety in your brain is complex. Dopamine pathways may affect social anxiety in several ways.[ix] For example, drugs like Olanzapine inhibits dopamine D2 receptors which provide its anti-anxiety benefits.
Dopamine signaling also helps promote feelings of self-confidence and self-esteem which helps to reduce anxiety disorder. Which is the reason why some people with social anxiety respond well to drugs like Wellbutrin which help boost dopamine use in your brain.[x]
See the next section for more on nootropics like L-Tyrosine, Folate and L-Theanine which help boost dopamine and dopamine use in your brain.
Norepinephrine
Norepinephrine plays a complex role in anxiety states. Social anxiety can be reduced by modulating norepinephrine in your brain.
For example, propranolol (which is classed as a beta-blocker), an antagonist of beta2-norepinephrine receptors, is used to reduce a rapid heart rate, tremors and quivering voice that you get when you’re about to step on stage in front of an audience.[xi]
Some SNRI’s (serotonin–norepinephrine reuptake inhibitors) are also effective in quelling social anxiety symptoms.[xii] Drugs like Cymbalta help boost serotonin and norepinephrine activity in your brain.
You can naturally boost serotonin and norepinephrine activity by supplementing with Saffron.
And several natural nootropic alternatives to beta-blockers are available. Nootropics like magnesium, L-tryptophan and St. John’s wort are used by many to treat social anxiety. More on these beta-blocker alternatives in the next section of this post.
Glutamate
Glutamate is your primary excitatory neurotransmitter. And is involved in every neuronal pathway in your brain and body. Including those that affect social anxiety.[xiii]
NMDA receptors are also particularly important for social anxiety disorders. NMDA receptors are glutamate receptors and are involved in learning and memory. Activation of the NMDA receptor triggers protein synthesis. Which strengthens the connection between neurons.[xiv]
This NMDA activity in learning and memory is likely one of the reasons why Cognitive Behavior Therapy is sometimes effective in treating social anxiety. Because you are put into situations that help you ‘unlearn’ certain situations that make you uncomfortable.
But forcing you to walk into a crowded bar and ask for the phone numbers of 50 female strangers. Simply to ‘unlearn’ the social anxiety that keep you from meeting new people. Seems like cruel and inhumane punishment to me. And does nothing for stress relief. There has to be better way.
And it turns out there is. Nootropics like Cat’s Claw, many of the racetam’s, L-Theanine, and Noopept all modulate NMDA receptors and glutamate.
Other Neurotransmitters
Several other neurotransmitters can play a role in social anxiety. And the associated systems involving fear and anxiety. Including neuropeptides, corticotrophin-releasing factor (CRF) and cannabinoids.
But none of the experimental compounds associated with these neurotransmitters have resulted in FDA-approved drugs. The excuse they provide is the stringent criteria for approval of these treatments.
I’d guess that money plays more of a role than “stringent criteria”.
You can’t easily patent and charge exorbitant prices for compounds like cannabis which in low doses is a very effective social anxiety treatment.[xv]
Another example is Noopept which is based off the endogenous neuropeptide cycloprolylglycine (CPG). Researchers in Moscow found Noopept similar to Piracetam in not only it’s nootropic effect, but also anxiolytic activity.[xvi]
Recommendations of Nootropics for Social Anxiety
If you are currently being treated for social anxiety. Or suspect you may be dealing with undiagnosed social anxiety or generalized anxiety disorder. And are looking for a more natural, safer way to treat your symptoms. Nootropics may help.
Natural Alternatives to Beta Blockers
In the section above on norepinephrine we found that prescription beta-blockers are often used to treat anxiety. Some natural Beta Blocker alternatives include:
- DHA (Omega-3) – fatty acids make up a significant portion of your brain cell membranes. Low levels of Omega-3’s can result in ADHD, anxiety, depression, suicide and an increased risk of Alzheimer’s and dementia. Recommended adult dosage for DHA is 1,000 mg per day. And half that of EPA. Try 3 GelCaps of my favorite Omega-3: Performance Lab® Omega-3
- Magnesium – a magnesium deficiency can cause brain fog, mental fatigue, social anxiety, and depression. Plasticity of neuron synapses is affected by the presence of adequate magnesium in brain cells. Choose a high quality chelated magnesium and use 400 mg before bed: Magnesium Glycinate (Amazon)
- St. John’s wort – has been used for centuries to treat anxiety, depression and stress. St. John’s wort works by preventing the re-uptake of serotonin in your brain. Much like prescription anti-depressants. Try: Nature’s Way – Perika (Amazon)
A quick note about Vitamin D. Excessive levels of this vitamin can affect the way your body and brain processes calcium. Calcium channels in your brain are implicated in social anxiety. You absolutely need adequate Vitamin D levels in your body. Just don’t overdo it.
Alternatives to SSRI’s, MAOI’s and other anti-anxiety drugs
Rather than separate these into how each affects the various neurotransmitters that affect social anxiety. I’m listing them in alphabetical order.
Please do the research on each nootropic before trying it. Especially if you are currently using any prescription drugs.
- Aniracetam – This member of the racetam-family of nootropics works with dopamine D2 and D3 receptors in your brain. And desensitizes AMPA (glutamate) receptors. Aniracetam is one of the most effective antidepressants I’ve ever tried. And its effects on dopamine in your brain can have a profound effect on anxiety symptoms. Recommended adult dosage is 750 mg Aniracetam twice per day (with 300 mg CDP-Choline).
- Ashwagandha – This adaptogen has been used for millennia to relieve anxiety, fatigue, restore energy and boost concentration. Clinical studies have shown Ashwagandha can repair and even reverse damage caused in the brain caused by chronic anxiety and stress. Try KSM-66 300 mg once or twice per day
- Bacopa Monnieri – This adaptogen has been used since ancient times to reduce anxiety, depression and stress. It protects your neurons and balances neurotransmitters. 150 mg Bacopa Monnieri extract in my favorite: Mind Lab Pro® v4.0
- Cacao – Cacao and dark chocolate (75%+ cacao) stimulates the release of phenylethylamine (PEA) which boosts focus and awareness. And increases anandamide (the bliss molecule) which helps you feel good. Cacao is a source of tryptophan which is the precursor to serotonin. And theobromine which boosts blood flow, is a stimulant, and may account for chocolate’s aphrodisiac qualities.
- Folate – Vitamin B9 (folate) is a cofactor in the synthesis of dopamine, norepinephrine and serotonin. Folate is also involved in gene expression, protein synthesis, and myelin synthesis and repair. It’s even involved in cerebral circulation. Powerful anti-anxiety treatment in this B-vitamin. Get a therapeutic dose of natural methyl-folate in: Life Extension BioActive B-Complex
- Ginkgo Biloba – This tree native to China has been used for thousands of years to boost mental alertness, improve cerebral circulation and for overall brain function. Many have found Ginkgo to be very effective in reducing stress and social anxiety. And boosting overall mood.
- Ginseng – Panax ginseng is used as a memory booster, improves mood, lowers anxiety levels and boosts stamina and endurance.
- Gotu Kola – Gotu kola is one of the most important herbs in ancient Ayurvedic medicine. This herb helps boost nerve growth factor which can have a profound effect on social anxiety. Many report that Gotu Kola may be even more effective in reducing anxiety and relieving stress than Ashwagandha.
- Kava – Kava is native to the South Pacific. And the islanders use kava for its sedative effects. Kava can help reduce anxiety and improve mood. Unlike benzodiazepines, kava does not impair cognitive function. In fact, studies show kava may boost cognitive function.
- Lemon Balm – Lemon balm is used for its anti-anxiety effects. Rosmarinic acid, a compound found in lemon balm, inhibits the enzyme GABA transaminase. Which in turn helps maintain adequate levels of GABA in your brain. Resulting in a calming effect. I recommend: Zazzee Organic Lemon Balm extract (Amazon)
- L-Theanine – L-Theanine naturally occurs in green, black, and oolong tea. This amino acid is used as a nootropic for social anxiety, learning & memory, mood, and focus. It works quickly in your brain to support GABA, dopamine and serotonin. You’ll get an effective 100 mg dose of L-Theanine (as Suntheanine) in my favorite: Mind Lab Pro® v4.0
- Rhodiola Rosea – Rhodiola activates AMPA receptors in your brain. Which helps decrease depression and stress-related mood swings, reduces fatigue, stimulates energy and alertness and boosts cognition. Get Rhodiola Rosea extract in my favorite: Mind Lab Pro® v4.0
- St. John’s wort – This plant has been traditionally used for mood disorders and wound healing. Today it’s used mostly as a treatment for social anxiety, depression and stress. St. John’s wort works by inhibiting the uptake of serotonin, dopamine, GABA, glutamate and norepinephrine. But please read the precautions for using this nootropic in the extended article. Try: Nature’s Way – Perika
(Amazon) - Tryptophan – This amino acid is a precursor to serotonin, melatonin and niacin (Vitamin B3) in your brain. L-Tryptophan is used to treat anxiety, ADHD, depression, insomnia, memory loss, pain and eating disorders. You’ll get 250 mg L-Tryptophan in: Performance Lab® Sleep
- Vitamin B6 – Vitamin B6 helps your brain make serotonin, norepinephrine and melatonin. The activated form of Vitamin B6 called P-5-P is particularly effective in boosting serotonin and GABA in your brain. And providing potent anti-anxiety effects. Get a therapeutic dose of Vitamin B6 (P-5-P) in: Life Extension BioActive B-Complex
- Vitamin B12 – This B-vitamin plays a key role in the efficient conversion of carbohydrates to glucose – your cell’s source of fuel. It also helps your body convert fatty acids into energy. Supplementing with Vitamin B12 (methylcobalamin) can help lower social anxiety, and elevate alertness, cognition, energy, vision, elevate mood and relieve insomnia. No more mood swings! Get a therapeutic dose of Vitamin B12 (methylcobalamin) in: Life Extension BioActive B-Complex
Social Anxiety Eliminated
Nootropic supplements are a strong alternative to many anti-anxiety medications currently prescribed by doctors. And promoted by the Big Pharmaceutical companies.
I encourage you to try some of the supplements I reviewed in the article above. Try them one-at-a-time until you find one or two that works. All it takes is a day or two to try each nootropic supplement to see if you get any relief from your social anxiety symptoms.
But a very strong word of caution – if you are currently using any prescription anti-anxiety or antidepressant medications. Or any medications for that matter. Research each nootropic including side effects and prescription drug interactions before using them.
You can eliminate social anxiety once-and-for-all with nootropics. If you do your research. And are willing to experiment until you find the one or two that is right for you.
Join The Discussion - 228 comments
Mick
May 28, 2019
OK David I will try it
Thank You for your help.
Mick
May 28, 2019
Hi David
Thank You for consultation that we had, it was very informative.
The nootropics that you recommended for me to try for social anxiety are:
Gaba
1. Oat Straw
Gotu Kola
Panax Ginseng
Holy Basil extract
2. Ashwagandha
3. Bacopa Monnieri
I started with Bacopa on 3rd of May. I’m taking it for 25 days now and unfortunately I don’t feel any effect. Research shows that full effect from bacopa can be felt from 1 to 3 months of taking it. Usually with me if nootropic works, I can feel it shortly after taking it.
Do you think there is a point for me to wait for another 2 months to see if it works?
Or should I stop taking it, and start another nootropic that you recommended?
David it would be very helpful if you could tell me, how long should I take each nootropic that you recommended, to see if it works? Not to waste any time.
For example:
Bacopa Monnieri – from 1 to 3 months.
GABA – up to………
Oat Straw –
Gotu Kola –
Panax Ginseng –
Holy Basil extract –
Ashwagandha –
Thank You David for your help.
David Tomen
May 28, 2019
Mick, many of these supplements should provide an effect you can feel within the first couple of doses. Bacopa seems to be the exception to this. But if you’ve not had any relief in 3 weeks I’d try something else.
I’d give you a specific order to try them in but my suggestions would not be based on any real science. All you can do is go through the list until you find something that works for you.
Óscar
May 12, 2019
Hello, I would like to ask about my nephew, he is 17 years old, and for years he suffers from a problem of several symptoms very badly misdiagnosed by the psychiatrists who continuously change his medication because it does not have the expected effect in any case. He has a great anxiety that transforms in numerous cases into paranoia, a lot of anger and impotence, inability to understand things and a lot of superficiality in his thoughts, seclusion at home and total disappointment with life and people. You are now being treated with riserlidone 1 mg but it is the same. We did not want to medicate him anymore since they wanted to give him antidepressants as well and we desperately look for something that works without the undesirable effects of all the medication that has been taken so far. In Spain there is very little information on nootropics and I would like to ask for help on what combination it could take to be effective and the doses in each case. I thank you very much for all your dedication, thank you!
David Tomen
May 12, 2019
Óscar, I understand your concern but it is not possible to recommend a specific nootropic stack for your nephew and expect results.
Please read this post again so you understand that you must experiment with various supplements addressing each possible cause until you find something that works.
To reduce the anxiety and paranoia you describe with natural supplements takes dedication and work until you find what works for you. There is no magic pill.
And each of the nootropics reviewed in this post links through to a full review which included dosage recommendations.
Eve
May 11, 2019
Greetings from Catalonia !, is it possible that the daily combination of Mind Lab Pro and Performance Lab Energy along with magnesium and Omega 3 can reverse social phobia, agoraphobia, lack of memory and lucidity? I have read many combinations and I am very confused. I can not concentrate to find the best with so many options … My medication now for years is diazepam 5 mg once a day (sometimes 2 times) is the only thing that has helped me minimally for social phobia and agoraphobia but I want to leave it if I feel that with the nootropics I overcome the symptoms. Thank you very much for all this valuable information and generosity !!
David Tomen
May 12, 2019
Eve, Mind Lab Pro and Performance Lab Energy will help with overall cognition. But cannot be compared to something as potent as diazepam for social anxiety.
I suggest you research “how diazepam works in your brain”. And if it does provide some benefit then look for nootropics that also work on GABA similar to this prescription drug.
Do a search of Nootropics Expert for “benzodiazepine” and you’ll get results like: Ashwagandha, Bacopa Monnieri, Kava Kava, and Valerian.
I suggest looking at the review on this site for each nootropic. And then try the supplements that look attractive to you one at a time. Until you find something that works for you.
Eve
May 12, 2019
really thank you David!
Xénia
May 8, 2019
Gracias por toda esta valiosa información!
Mi pregunta es que si tomo Mind lab pro y además quiero tomar también un compuesto eficaz de nootropicos diseñado para fobia social, ¿cual me aconsejaría que fuera compatible con mind lab pro? Un fuerte abrazo!
Xénia
May 8, 2019
Me refiero a utilizar además de Mind lab pro, otro compuesto de nootropicos eficaz para fobia social. Gracias!
David Tomen
May 9, 2019
Xénia, it depends on what is causing your social phobia (anxiety). I suggest you go through each of the neurotransmitters described in this post and try a precursor to boost that neurotransmitter to see if it helps. But do one at a time.
For example, to find out if you are low in dopamine, try supplementing with extra L-Tyrosine or NALT and see if it helps. Do that for each neurotransmitter until you feel a difference. Then you know you are on the right track. And work on that pathway in your brain until you no longer deal with social phobia.
Drew
May 7, 2019
Hi David,
Over the last couple of years i have become increasingly interested in bio hacking, inadvertently at first starting with multivitamins and stimulants to help supplement a very physically active lifestyle, i discovered i was vit b & iron deficient and this uncovering aswell as the dramatic changes in mental and physical well being i experienced once i began supplementing these vital vitamins fuelled my passion to further better myself by understanding and attempting to rectify many other issues i have.
I have had stammer/stutter from a very young age, which doctors explained was most like the result of a very traumatic period i was subjected to as a child. Out of all my other interest in biohacking, understanding the connection between my psychological state and how it both subconsciously and consciously effects my ability to speak drives me the most, as ive never truly understood why i speak fluently in some pressured situations and stammer out of control in some less pressured environments and vice versa, aswell as never stammering when im by myself.
Obviously i do not expect a “cure” for this social disability as the deep seeded roots of the disorder are most likely intertwined within my neural pathways and carved into my mind through repetition and learned behaviour as a child, however i would like to know if you have any knowledge or research on any natural supplementation that has shown to affect people suffering with speech impediments such as stuttering, or similar involuntary behaviours such as tourettes?
Id expect any supplements that effect muscular over tightening, involuntary spasms, anxiety, mental blockage, lack of self confidence, tension in the body or repairing cognitive behavioural issues would be worth a try.
Kind Regards,
Drew
David Tomen
May 7, 2019
Drew, this stammering issue could be caused by any number of things which is likely no surprise to you. I suggest you start experimenting one at at time with things that boost acetylcholine, dopamine, serotonin and GABA. And see if any one of those precursors makes a difference. The suggestions in this post may be a good place to start.
For example; Alpha GPC or CDP-Choline for acetylcholine, L-Tyrosine for dopamine, L-Tryptophan for serotonin and GABA. But do each separately for 2 or 3 days and see if you get any benefit. Once you start noticing a difference then you know to pursue that path.
Drew
May 10, 2019
Thanks David,
i have already been taking L-Tryptophan for the serotonin to regulate my sleep better, aswell as L-Tyrosine for mild anxiety and stress support. And after watching your Video comparing the best Choline supplements i have purchased both Aplha GPC & CDP- Choline to add to my nootropics stack.
Once again thank you for your reply and i look forward to keeping up to date with future videos.
Nanda
March 23, 2019
Hello David I have followed your work for some time. I am 32yrs old and i have always felt difficult to finish mundane things right from my childhood. It has affected my professional life as well. Never knew what ADD was until recently. But the symptoms seems to fit exactly with ADD. My problems areas are attention for long time, procrasination until the last moment, lack of proper sleep, low self esteem, day dreaming, fear of failure, anxiety while interacting with strangers in my professional circle.
figured out Dopamine could be the issue. Below is my stack that am currently on for the last three weeks. I could defintely see some difference in my mood. Am i on the right track here and what are your recommendations. Kindly let me know. Thanks
Morning empty stomach
L-Theanine – 500mg
L-Tyrosine – 500mg
Aswagandha – 400mg
After Breakfast
DHA – 1000mg
Multivitamin
Late Afternoon
L – Tyrosine – 500mg
DLPA – 500mg
Late Evening
L – Tryptophan
B Complex Cap
Gotu Kola
Night
L- Theanine – 500mg
David Tomen
March 24, 2019
Nanda, you are definitely on the right track. You may want to do something to increase acetylcholine as well.
Please see the stack for ADD I recommend in this post for nootropic suggestions, dosage as well as timing: https://nootropicsexpert.com/best-nootropics-for-adhd-add/
At the very least I’d suggest L-Tyrosine + ALCAR and/or Alpha GPC or CDP-Choline in the morning, at noon and possibly another dose around 4 PM. Add them to the rest of your current stack.
Kayla
February 19, 2019
Hi David, I’m a 21 y/o college student diagnosed with social anxiety and clinical depression. My anxiety is more situation and comes and goes, but it causes physical symptoms such as poor concentration, migraines, back aches, etc. Tried Aniracetam but it didn’t work. Have been taking magnesium for a month now, with no noticeable success. What would you recommend? Thanks!
David Tomen
February 20, 2019
Kayla, go back to “Anxiety is a Neurotransmitter Problem” and read through each neurotransmitter and suggestions on how to support each. You’ve started experimenting and must continue until you find the root cause of your anxiety and depression. You may want to try one nootropic from each section above and see if there is any improvement. But I wouldn’t take them all together because you’ll not know what is working.
This is a classic case of trial and error until you get to the heart of your problem.
Have you ever used a prescription drug and had any success with it? If you have, find out the mechanism of action for that drug and find a natural alternative for it.