Nootropics for brain injury and repair

How to Create the Best Nootropic Stack

David Tomen
Author:
David Tomen
16 minute read

most effective nootropic stack

If you’ve spent any time here on Nootropics Expert®, you have a good idea how certain nootropics can benefit your brain.

But if you’re just getting started with nootropics, the choices can seem overwhelming. Will one nootropic work? Will it take more that one supplement to solve my problem? If more than one, how do I combine other nootropics for best results?

Here are some tips that should help …

Nootropics for ADHD & ADDIf you are a university student, an entrepreneur, a business executive, a stay-at-home mom or dad, or a senior – what are you trying to improve?

It could be just one thing you want to work on. Like improving your memory. Maybe you have a difficult time focusing like I did. Or you find learning new material, skill or language an insurmountable problem.

You could have an issue with anxiety, or bouts of depression. Procrastination could leave you feeling like a failure because of a lack of motivation.

Put some thought into this now because you’ll save yourself a lot of time and money by figuring out what you are trying to fix first.

If it’s just one thing you want to fix or support, you’ll have an easier time putting together the right beginner nootropic stack. And often it will only take 3 or 4 supplements to get you where you need to be for your own nootropic stack.

Later in this post you’ll get specific suggestions on nootropics for:

For many of us, it’s more than just one problem we’re dealing with.

In my case, the combination of Adult ADD and hypothyroidism caused problems with anxiety, cognition, focus, memory, and depression. That’s a lot to deal with and a lot to fix.[ii]

The good news is it’s entirely possible with the right combination of your own nootropic stacks to address each of these issues. My life is a good example of what’s possible with the right nootropic stack.

I was able to restart my career. My marriage is better than I ever dreamed possible. And my future looks amazing. All due to an experienced nootropic stack regimen, if you will.

But to be perfectly honest with you, one nootropic that works for me, may not work as well for you. Each of us have unique brain “wiring” when it comes to nootropic stacking.

Our chemical makeup is different. And is affected by foods we eat, where we live, the air we breathe, the genes we inherited from our parents, and more.

So experimentation is key. Pick your top choice of something you’d like to improve. Once you find something that works reasonably well, go to the next thing on your list.

With time, effort, and diligent experimenting you’ll find the perfect nootropic stack for you.

Your First Nootropic Stack

My recommendation is to create your own nootropic stack when starting out.

Nootropics to improve memoryTailor your stack to each issue your trying to solve. It’ll likely be more expensive because you need to get each individual nootropic or supplement.

The advantages at first outweigh the cost in my opinion. When you find something that works, you then need to figure out how much of that nootropic works best with your brain and body.

If you try something and it doesn’t work as well as expected, or what you were promised in the marketing hype, or what you read on the forums – pitch it.

And try something else.

Flexibility and experimentation is key when you’re getting started with nootropics. A pre-formulated stack doesn’t allow that flexibility.

Keep that pre-formulated option in reserve until you nail down what works best for you. Then look for a nootropic stack that fills all your requirements.

Let’s briefly look at some of your options for major issues to get you started. This is by no means an exhaustive list but a way to point you in the right direction.

Use the search function on Nootropics Expert to find every nootropic that works for memory, or depression, or anxiety, or ADHD, or traumatic brain injury, or whatever it is you need to fix or improve.

How to create the best nootropic stack

Nootropics for Cognition, Thinking and Decision-Making and Nerve Growth Factor

Cognition is the mental action or process you go through when learning something new and understanding it through thought, experience and your physical senses.[iii]

Cognition includes thinking, knowing, short-, working-, and long-term memory, decision-making and problem solving.

That’s a tall order to cover and will likely take more than one nootropic. You can start with:

Nootropics for Memory and Cognitive Function

We use several different types of memory every day. Short-term memory is also known as primary or active memory. And is limited to what you remember for 20 to 30 seconds.

Long-term memory is the type of memory associated with an event or information you acquired long ago. This is a complicated form of memory influenced by your perception of an event or thing, conditioning or any other input. And is encoded using long-term potentiation and strengthening neurons and synapses.

Working memory is distinct from short-, and long-term memory. These are memories that are not only remembered, but simultaneously processed with information that is important to you. You remember the purpose of the information, and why you decided to remember it.[iv]

Each type of memory can be assisted by different nootropics. Because neurotransmitters, cerebral blood flow, long-term potentiation, hormones and more all come into play for memory.

  • Alpha GPC or CDP-Choline. Both nootropics help boost acetylcholine (ACh) in your brain. ACh is associated with memory and learning.
  • DHA (Omega 3). DHA makes up a large portion of your brain’s gray matter. This fatty acid helps form cell membranes, neurons and synapses which are needed to form and encode memories.
  • Huperzine-A. Hup-A helps promote memory by increasing acetylcholine levels.
  • L-Theanine. Found naturally in green tea and available as a nootropic supplement, L-Theanine helps boost dopamine and serotonin. Improving anxiety, focus, learning, and mood.
  • Noopept. Noopept stimulates dopamine, nicotinic and serotonin receptors in your brain. Boosting cognition, memory, retention, logical thinking, improving your reflexes and mood.
  • Phosphatidylserine (PS). PS is vital for brain health. Highly concentrated in cell membranes, PS helps in the release, storage and activity of neurotransmitters and receptors. Boosting cognition, focus, memory and recall.
  • Piracetam. The original nootropic, Piracetam influences AMPA and NMDA receptors in your brain. Affecting learning and memory.

For more options and to learn more about how memory works, see my post on:

Best Nootropics for Learning and Memory

nootropics-relieve-anxiety-and-depression

Nootropics for Anxiety and Depression

Do you remember what it used to be like to be in a ‘good mood’ all of the time? Anxiety and depression are something most of us have had to deal with at one time of another.

For me, being Adult ADD and hypothyroid was like a double whammy. And it took a while to dig out of the hole I was in.

Anxiety[v] and depression[vi] are often ‘grouped’ together both in nootropic circles as well as in the psychiatric/medical world. But they are two distinctly different conditions. Even though the cause of anxiety and depression may overlap.

All kinds of conditions can contribute to anxiety and depression. Neurotransmitter levels that are out of balance can cause severe depression. Illness and stress can cause anxiety and depression.

Poor cerebral blood flow, a lack of Brain-Derived Neurotrophic Factor (BDNF), mental fatigue from lack of cellular energy, Alzheimer’s, Parkinson’s, stroke and more can all cause anxiety and depression.’

Here are a few nootropics that can help. This is by no means an exhaustive list.

And if your depression or anxiety is severe, please, please seek professional help while you’re exploring your nootropic options.

  • Aniracetam. This member of the racetam-family of nootropics, Aniracetam is very well known for helping anxiety and depression. And one of my favorites. Aniracetam activates D2 and D3 dopamine receptors in your brain. Improving anxiety, cognition, learning, memory and mood.
  • Alpha GPC or CDP-Choline. Both nootropics help boost acetylcholine (ACh) in your brain. ACh is associated with memory and learning. And the choline is needed when stacked with any racetam.
  • Ashwagandha. Used for thousands of years in Ayurvedic medicine, Ashwagandha helps relieve stress, fatigue, restores energy and concentration, and normalizes blood sugar.
  • Bacopa Monnieri. Bacopa is believed by some to be the best nootropic available today. This adaptogen helps prevent chemical and physical stress instead of suppressing them like many modern antidepressants.
  • Lemon Balm. This plant from the mint family, Lemon Balm inhibits the GABA transaminase enzyme. Which in turn helps maintain adequate levels of GABA in your brain. Resulting in a calming effect and relieving anxiety and depression.
  • Rhodiola Rosea. Rhodiola increases AMPK which helps decrease depression and stress-related mood swings, reduces fatigue, stimulates energy and alertness and boots cognition.
  • Sulbutiamine. Synthesized in the lab from Vitamin B1 (thiamine), Sulbutiamine is another favorite of mine because it boosts memory, motivation and is a heck of an antidepressant.
  • Vitamin B6. B6 is a required coenzyme for the synthesis of most major neurotransmitters in your brain. And helps enhance alertness, cognition, energy, memory and mood.
  • Vitamin B12. B12 is essential for the synthesis of DNA, RNA and neurotransmitters in your brain. B12 enhances alertness, cognition, memory, decision-making and mood.

To learn more about anxiety and depression, and even more options on nootropics that can helps alleviate the symptoms of each, see my posts on:

Best Nootropics for Anxiety

Best Nootropics for Depression

nootropics-for-mental-energy

Nootropics for Energy and Motivation

If you’ve ever felt mentally drained after writing an exam, an intense study session, a misunderstanding with your partner, or working out a business problem ▬ nootropics can help.

Energy and motivation kinda’ go hand-in-hand in my book.

When I’m energized, it usually translates into motivation to get things done. When energy stores are depleted in my brain and body, I’m burned out and nothing much is going to happen.

Mental fatigue has a variety of causes. Depleted neurotransmitters can cause fatigue as well as a host of other issues. A lack of Adenosine Triphosphate (ATP) which is the energy source for brain cells is another cause of mental fatigue. And leads to neurodegenerative disease.

Hormones that are out of balance can cause fatigue. And poor cerebral blood flow which provides oxygen and nutrients to brain cells can result in fatigue.

The amount of available mental energy has a direct influence on cognitive and mental performance. Let’s look at the nootropics that can fix mental fatigue and boost motivation.

  • Acetyl L-Carnitine (ALCAR). ALCAR boosts acetylcholine (ACh) and transports fatty acids through cell membranes into mitochondria for use as brain cell fuel. One of my favorite nootropics, ALCAR increases memory, mental alertness, fluid thought and is a powerful antioxidant.
  • Alpha Lipoic Acid. Lipoic acid boosts levels of acetylcholine (ACh) and glucose uptake. And regenerates depleted antioxidants already present in your brain including Vitamin C, Vitamin E, glutathione and CoQ10. Boosting cellular energy and memory.
  • Coluracetam. One of the newer racetams, Coluracetam works as a choline uptake enhancer. And improves AMPA potentiation. The net result is a boost in energy levels. Unlike prescription stimulants, Coluracetam offers a more relaxed, calm and free-minded kind of thought-processing.
  • CoQ10 & Ubiquinol. CoQ10 is essential for producing Adenosine Triphosphate (ATP) that fuels the mitochondria in brain cells. Improving athletic performance, works as an antioxidant, and battles fatigue and depression.
  • Creatine. Creatine acts as fuel for your brain cells. And provides ‘energy on demand’ when you need it.
  • NADH. NADH is a coenzyme used in the formation of ATP, the energy source for mitochondria in your brain cells. NADH boosts alertness, mental performance, energy and memory.
  • Noopept. This peptide-derived nootropic related to the racetam family, Noopept increases BDNF, and stimulates dopamine, nicotinic and serotonin receptors. Boosting energy, cognition, memory, logical thinking, and improves reflexes and mood.
  • Phenylpiracetam. A Russian derivative of Piracetam, Phenylpiracetam improves concentration, memory, motivation, mental energy and offers a stimulant effect.
  • Rhodiola Rosea. Rhodiola increases AMPK which triggers the use of stored energy from fats in your brain cells. Boosting alertness, energy and cognition while decreasing depression and stress-related mood swings.
  • Pramiracetam. A derivative of and more potent than Piracetam, Pramiracetam stimulates choline uptake in your brain. Boosting energy levels, providing focused stimulation for better mental drive and motivation.

To learn more about, and see even more options for energy and motivation, see my post on:

Hacking Motivation with Nootropics

Nootropics for Brain Repair and Maintenance

According to the American Center for Disease Control (CDC) an estimated 1.7 million in the US suffer from Traumatic Brain Injury every year.[vii]Nootropics for brain injury and repair

And that’s just for the USA. This is clearly a world-wide problem for the human race.

Brain injury covers a lot of territory and includes concussion, Post Stroke Syndrome, sports and athletic injuries, damage from pharmaceuticals, environmental toxins, bad food and water, polluted air and more.

The mechanics of injury can affect cerebral blood flow, torn tissue, damage to neurons, altered brain waves and neurotransmitters, free radical and oxidative damage and more.

Now the “official” line from the FDA and other governmental authorities in the USA and many countries world-wide, nootropic supplements and other ‘natural’ substances cannot repair brain injury.

While this is certainly not medical advice, and you should absolutely seek professional medical help for brain injury, neurohackers have found relief on their own experimenting with nootropics. Here’s a small sample of what we’ve found useful:

  • CDP-Choline. CDP-Choline provides your brain with choline which aids in the synthesis of acetylcholine (ACh). And cytidine in CDP-Choline converts to uridine which is important for neural membrane synthesis.
  • DHA (Omega 3). DHA makes up a large portion of your brain’s gray matter. This fatty acid helps form cell membranes, neurons and synapses which are needed to form and encode memories.
  • Phosphatidylcholine (PC). PC is a phospholipid which helps build and repair brain cell membranes.
  • PQQ. The enzyme cofactor PQQ facilitates the growth of new mitochondria in your brain cells. Boosting the production of nerve growth factors in cells that support creation of new neurons. And reduces inflammation and oxidative stress.
  • Pramiracetam. This derivative of Piracetam, Pramiracetam increases acetylcholine receptors in your brain. By stimulating choline uptake in your brain, this nootropic boosts energy levels and improves cognition and motor coordination.
  • Pterostilbene. Found in cranberries, blueberries and grapes, Pterostilbene is a potent antioxidant, stimulates Brain-Derived Neurotrophic Factor (BDNF), and promotes neuroplasticity. By reducing oxidative stress, Pterostilbene helps prevent heart attacks and stroke.
  • Resveratrol. This polyphenol antioxidant found in the skin of grapes, Resveratrol improves blood flow and reduces inflammation. Improving cell survival and neurogenesis in the hippocampus, resulting in better memory and learning.
  • Turmeric. Turmeric is unique in its ability to reduce inflammation common to Parkinson’s, Alzheimer’s and brain tumors.

To learn more about PTSD and Traumatic Brain Injury, and the best nootropics to alleviate the symptoms of each, see my posts on:

Treating PTSD with Nootropic Supplements

Best Nootropics for Traumatic Brain Injury

Conclusion

There are many ways to address each issue you’re dealing with when it comes to optimizing brain health and function.

If you’re a nootropic veteran I’m sure you’ll find holes in my recommendations. Each section is most definitely not a conclusive list of nootropics for a single condition.

I encourage you to use the “Search” function on Nootropics Expert®. Enter the issue you’re dealing with and you’ll get a list of articles with suggestions for your nootropic stack.

By no means should you include everything listed under “memory” for example in your stack. One or two options from each section can help you toward your ideal nootropic stack.

Many nootropics work synergistically and together can make a more powerful solution than a nootropic on its own. When combining several nootropics in a stack you’ll want to back off to the lowest recommended dose of each to start.

You also may have noticed that some nootropics appear in several categories. What this means is most nootropic stacks would benefit by including Alpha GPC or CDP-Choline, DHA, and a nature-identical B-Vitamin Complex.

Be sure to click through to each nootropic to review dosage recommendations and side effects. Each article has extensive references to clinical studies as well.

Pre-Formulated Nootropic Stacks

Early in this article I mentioned pre-formulated stacks as an option that you could use to replace individual nootropic supplements.

Finding the right pre-made stack can save you time and often quite a bit of money.

After experimenting with many of the well-known stacks, I settled on Mind Lab Pro®.

Mind Lab Pro contains therapeutic dosages of 11 top quality natural nootropics including; CDP-Choline, Bacopa Monnieri, Lion’s Mane Mushroom, Phosphatidylserine (PS), N-Acetyl L-Tyrosine (NALT), L-Theanine, Rhodiola Rosea, Pine Bark Extract, and Vitamins B6, B9, and B12.

I’ve found it less expensive to use this stack than buying each nootropic on its own. All I’ve had to add is coconut oil, DHA, Aniracetam and Sulbutiamine.

And I’ve recently replaced separate supplements including ALCAR, Alpha Lipoic Acid, CoQ10 and PQQ with Performance Lab® Energy which contains all four nootropics in the dosages I was using. And is less expensive than buying separate supplements.

Check out my reviews on Mind Lab Pro® and Performance Lab® Energy and see if they could work for you too.

If you have questions about building your perfect nootropic stack, please leave a comment in the comment box below. I or another experienced neurohacker in our community will help you out.

As an Amazon Associate I earn from qualifying purchases. This post may also contain other affiliate links and I will be compensated if you make a purchase after clicking on my links.

[i] “Attention deficit hyperactivity disorder” Medline Plus U.S. National Library of Medicine (source)

[ii] Mayo Clinic Staff “Hypothyrodism” Mayo Clinic mayoclinic.org (source)

[iii] “Cognition” Frontiers in Psychology journal.frontiersin.org (source)

[iv] Cowan N. “What are the differences between long-term, short-term, and working memory?” Progress in Brain Research 2008; 169: 323–338. (source)

[v] “Anxiety Disorders” National Institute of Health nimh.nih.gov (source)

[vi] “Depression” National Institute of Health nimh.nih.gov (source)

[vii] “Get the Stats on Traumatic Brain Injury in the United States” U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES – Centers for Disease Control and Prevention (source)

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Join The Discussion - 118 comments

Stephan
April 7, 2020

Hi David!

I’ve been researching nootropics for about 6 months now. Over that period I’ve dabbled in experimentation a bit here and there and am now just starting to work on a stack and would appreciate some input.

Some background: I grew up with an exceptional memory. I spent a good 6 years of taking fasting to a bit of an extreme in the later schooling years, and was athletic. My history of getting sick was almost non-existant. Six months into college I fell ill and over time became more prone to becoming sick and my memory taking a 180. Also I have developed frequent headaches years after falling ill. I should also note that I stopped fasting when starting college. During college I was also meditating for several hours a day. Most frequently my headaches affect my temples, but are not limited to the temples. I’ve lost the ability to dream, developed depression, and lost my spacial memory to the point where it is difficult to mentally recollect objects in a room immediately after stopping looking at them. Currently I do have a poor diet, but it is planned to be fixed soon.

Typically when I research I try to gain an overall picture by reading through multiple sources and try to weed out misinformation, but it is still difficult to wrap my head around all of the information. My two highly regarded resources are Nootropics Expert and examine.com.

Currently my stack is simple. I am currently taking these, and love the effects they give, but it is still missing something, as I will explain bellow.

Rhodiola Rosea – 500mg
Bacopa – 500mg
-Carnitine and Alpha lipoic acid is a part of the same supplement-
Acetyl L-Carnitine – 400mg
Alpha Lipoic Acid – 200mg
Turmeric powder – 400mg + Turmeric extract – 50mg
fish oil (can’t remember the dosage. I ran out so I don’t have a reference.)

Periodically I make an organic green tea ( I like it thick so I use multiple organic tea bags, newmans own), and half of the time I add turmeric and black pepper.

Once I get the chance, I plan on getting the nutrients from the diet if possible, otherwise I will be using supplements to help the balance.

The Rhodiola + Bacopa synergy has unquestionably helped with the memory loss. I’ve been taking it for about a week now so it still has time to build up in my system. It has also helped aleviate my depression, although I still feel as though it is missing something in regards to the depression, perhaps a neurotransmitter that is not involved in either of the two supplements.

Since my depression took a down turn, I got in the habbit of oversleeping, which the rhodiola has been helping with.

Currently I still have frequent headaches that are hard to explain, but I strongely suspect inflammation is involved, and the turmeric seems to be back and fourth on whether or not it helps.

Any help would be greatly appreciated! And I love your work on this website! You do a great job!

    David Tomen
    April 23, 2020

    Stephen, not enough information to make an informed opinion. I suggest booking a personal consultation with me so we can dig deeper into what is going on. And coming up with a solution. If you’re interested, please go here: https://nootropicsexpert.com/personal-consultations/

Sara marshall
November 19, 2019

Hello!
Im currently a student and i work part-time
Im starting to use the low dosafe of l-théanine+caffeine and rhodiola rosea
I usually take l-théanine+caffeine in the morning and after lunch i’ll take rhodiola rosea.
What can you tell me about the combination of these two?

Also what can you recommand me ?
the job and studies are very demanding and i want to be able to succeded at both!
thank you in advance

    David Tomen
    November 20, 2019

    Sara, what you are using depends on the dosage. But the L-Theanine + caffeine combo is more complex than you think. Which I explain in this review of Performance Lab Stim: https://nootropicsexpert.com/performance-lab-stim-review/.

    I’ve also just updated my Best Nootropics for Studying post which you’ll find here > https://nootropicsexpert.com/best-nootropics-for-studying/

      Sara
      November 21, 2019

      Thank you for your replay.

      I have been reading the article about the nootropics for studying and i decided to give it a try with the PERFORMANCE LAB STIM.
      Should I try too the MIND LAB PRO?
      What would be the correct way to take it? Both In the morning?

      Thank you

        David Tomen
        November 21, 2019

        Sara, I’d start with a capsule of Mind Lab Pro in the morning and another at noon. Performance Lab Stim is as needed. And it works very well. Use it instead of coffee or an energy drink. Nice clean feeling.

angela
July 30, 2019

hello

kindly suggest what nootropic stack can i use for my mother who has alzheimers and is 79 years of age. we live in india
after she recently had a seasonal bout of chest congestion ( she was admitted in the icu for a week and early on had never been admitted to a hospital before so was quite traumatic for her) , her brain symptoms worsened after coming home due to high antibiotic dose

am very grateful for your inputs and knowledge you have shared here.

Thanks again
angela

    David Tomen
    July 31, 2019

    Angela, I suggest getting her a high quality probiotic to re-establish her microbiome that was damaged from antibiotic use. And a good Prebiotic will help as well: https://nootropicsexpert.com/performance-lab-prebiotic-review/

    Then do a search of Nootropic Expert using the search function top right for the keyword “Alzheimer’s” and see what turns up. You’ll get several suggestions that may help. It’ll take some reading but it think worth doing.

Sky
June 9, 2019

Hi. I am 37 and it’s was only last month I realize there is nootropics that really helps the brain. I bring to read and realize I have a lot of symptoms Iike unable to concentrate and focus , loss of motivation and interest in stuff, tired easily , procrastinating, panic attack when there is crowd or social disorder. The first nootropic supplement was mind lab pro taken a month ago. I took 2 and the results was amazing within 1 hour. I got a clearer mind and full of energy but the bad thing is I got insomnia at night. The effects lasted me for 5 days but sadly on the 6th day , the effects are gone and I am bad to old one. I still took 2 in the morning but it’s has no effect to me at all. I regretted not cycling mind lab pro after 5 days as I believe it has build a tolerance on me. I am now on the 27th day ,I felt so depress now thinking it won’t work on me anymore. I believe I am lack of dopamine or serotonin so I decided to buy L tyrosine 750mg and L tryptophan 500mg. I took 2 capsule of l tyrosine with B6 in the day and 2 capsule of L tryptophan at night but I realize I am still the same old depress and lack of Motivation person .

I am currently on
Morning
1 multivitamin
2 L tryrosine (500mg)
1 b6 (50 mg)
1 vitamin c ( 1000mg )
1 mind lab pro
DHA

Afternoon
1 reservatrol
1 Cq10
2 Curcumin
1 mind lab pro

Night
2 tryptophan
1 B6

I email mind lab pro that I am not feeling the effects and should I cycle it and their reply was I am actually feeling it but I didn’t feel it. They advise me to take 1 in the morning and 1 in the afternoon. I really felt it was not working for me anymore. I am thinking to cycle after my first bottle for 5 days .

Can you advise me what can I do . I Really don’t know what supplement I can try now . Help needed thanks as I believe I been suffering this for almost 20 years

    David Tomen
    June 10, 2019

    Sky, one thing I’ve noticed with nootropics that the change can feel profound when you first start using them. But after awhile you don’t notice the difference as much. The reality is often a “new normal” that is not as noticeable. And unless you are really in tune with your body you may miss it.

    But let’s assume that you got zero benefit from the supplements you are using. The wisest thing to do is keep on experimenting. Don’t forget you are dealing with 20 years of things not working well. You need to realize that change can’t happen overnight. It will take time to repair 20 years of damage.

    Take a look at this post I recently wrote for other ideas: https://nootropicsexpert.com/how-to-improve-memory-and-concentration/. Don’t give up. You already experienced a bit of how powerful nootropics can be. Just keep on trying things until you find what works for you.

mark
June 5, 2019

Hi David,

This is a pretty informative article and as in your case i also have adult ADD and hypothyroidism. I also was diagnosed with anxiety and also thinking i have chronic stress and depression as those kind of “disease” is considered taboo in my culture and is being ignored. I am very new to nootropics and is still on the learning stage by buying nootropics that i can buy online and can get my hands into. So far i have tried moda, l-theanine, paracetam, omega 3, and b3 to to b6. I also im trying to start pregnenolone thinking it might have some effect on me. So far as i have tried, the current stack that works for me is moda, L-theanine. I am experimenting moda, l-theanine and piracetam. So far stacking these three seems to have little effect. One of the things though that i hate about moda is it makes me “sleepy” when i take it. as i have read online, some said that it has the reverse effect on people with ADD, is that true?

Thank you, i really need some advice on these nootropics.. I am also thinking of trying out mind lab pro and quila and one of my main issues is that its quite expensive to be shipped in my country and i have read negative comments on mind lab pro on non-delivery of products.

As a beginner with ADD and Hypo, what would you suggest for a good stack?

Thank you again david.

    David Tomen
    June 5, 2019

    Mark, it probably made you ‘sleepy’ because you are not supporting it with the nootropics needed for boosting dopamine and acetylcholine in your brain. If you boost the use of dopamine in your brain but there’s not enough dopamine then it won’t work well. Same thing with Piracetam. This racetam boosts the use of acetylcholine in your brain. But if you don’t have enough of that neurotransmitter it won’t work.

    Please see my post on ADD for a stack you can use that works: https://nootropicsexpert.com/best-nootropics-for-adhd-add/

    And for each nootropic, please look up the review for each here on Nootropics Expert and see dosage recommendations on how to use them.

Luciano
May 15, 2019

Hello David, greetings!

Thank you for your teachings. I want to boost my test performance. I would like to share my stack.

at 6 in the morning:
– With water and an empty stomach.
Acetyl-L Carnitine
Alpha GPC
Huperzine A
L-Theanine
NALT
Pine Bark Extract
Rhodiola Rosea
Lion’s Mane
BioPQQ
DHEA

30 minutes later:
– With 1 spoon of extra virgin olive oil
Bacopa Monnieri
Gotu Kola
Phosphatidyl Serine
Vinpocetine
Ubiquinol
DHA

    David Tomen
    May 16, 2019

    Luciano, couple of suggestions; only use Huperzine-A every second day because it has a very long half-life, and add a high quality B-Complex supplement to your stack. More on Huperzine-A including dosage recommendations here: https://nootropicsexpert.com/huperzine-a

      Luciano
      May 18, 2019

      Thanks, David!

      I realized that after taking this stack in the morning I get yawning a little above normal, even though I slept well. I have the perception that it is some of these nootropics. Was it L-Theanine, Rhodiola Rosea or another nootropic?

        David Tomen
        May 20, 2019

        Luciano, it could be caused either by by L-Theanine or something increasing acetylcholine too much.

Miguel
March 30, 2019

Hi David! A hug from Portugal!

I have been suffering from social anxiety for the last 20 years.

I was managing with clonazepam(2mg) and diazepam(5mg).,

Can you recommend the right stack to start without any interaction with my medication.

Thanks for your help.

    David Tomen
    March 31, 2019

    Miguel, both of the drugs you are using affect GABA receptors. So when researching any nootropic you think you’d like to try, make sure you read the “Side Effects” section here on Nootropics Expert. And avoid the supplements that are contraindicated with benzodiazepines.

    Please see this post which may help you figure out the root cause of your anxiety: https://nootropicsexpert.com/best-nootropics-for-social-anxiety/. Suggestions are offered throughout that post. And the last major section of the post offers suggestions of nootropics you can try.

    It’s not possible to recommend the right stack for you to start with dealing with anxiety without much more investigation. But hopefully that post will help you narrow down your choices.

    One way to help you figure out what is going on is to try a nootropic that helps or affects each of the major neurotransmitters in your brain.

    For example, if you think you have a problem with dopamine, try L-Tyrosine for a week and see if it helps. If not, then move on to serotonin and try L-Tryptophan for a week. And see if that helps.

    Keep going down the list until you start feeling better. That’s a hint that you are on the right track so you can keep exploring that particular area you may be deficient or dysfunctional in.

    If you’re still stuck then schedule a personal consultation with me and we’ll get to the bottom of it: https://nootropicsexpert.com/personal-consultations/

Markos
March 26, 2019

Hello sir, you have been doing an excellent job and have great youtube videos. Analytical accurate structured informative and many other things.

A question I have is:

Which nootropics increase nor-epinephrine?

also, apart from many symptoms I have, it is difficult to read a book. ( I could only read some times when I drank 10 to 20 cups of green tea but only in the initial period, and also some times when I took a lot of valerian.

anyway, any nootropics to be able to read passages of text and read books? Thank you

    David Tomen
    March 27, 2019

    Markos, Bacopa Monnieri was recommended to devotees in ancient India according to Ayurvedic texts so they could easily memorize long passages of text: https://nootropicsexpert.com/bacopa-monnieri/. But this is the type of nootropic that needs to be dosed correctly and used consistently day after day until you see results.

    Norepinephrine is naturally the next step in the dopamine pathway. So a nootropic like L-Tyrosine or Mucuna Pruriens will help synthesize dopamine which will go on to make norepinephrine.

    Use the search field top right of this site and search for “norepinephrine” and see if anything else turns up that may help boost norepinephrine.

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