Phenibut improves sex

Phenibut

David Tomen
Author:
David Tomen
14 minute read
Phenibut has a calming effect on brain and body, helps relieve stress and anxiety, and boosts Human Growth Hormone

Key Takeaways

  1. Phenibut is a GABA analogue that increases GABA levels in the brain, providing stress relief and reducing anxiety.
  2. It has been used in the treatment of neurological disorders such as PTSD, anxiety, depression, insomnia, and alcoholism.
  3. By raising GABA levels, Phenibut helps balance mood, promotes focus, relaxation, and positive mood, and counteracts irritability and restlessness.
  4. Phenibut should be used cautiously due to potential dependency, withdrawal symptoms, and adverse side effects.
  5. Phenibut dosage should start low at 200 – 300 mg per day, avoid alcohol or benzodiazepines, and purchase from reliable sources.

 

Phenibut (β-Phenyl-GABA, β-phenyl-γ-aminobutyric acid, Noofen, Citrocard) is an analogue of the inhibitory neurotransmitter GABA. The addition of a phenyl ring allows Phenibut to cross the blood-brain barrier (BBB). Neurohackers prefer Phenibut when the goal is to raise GABA levels in the brain because GABA as dietary supplement cannot cross the BBB.

Phenibut is an analogue of GABA and this is the chemical structure of each.
GABA-vs-Phenibut

Phenibut was developed in St. Petersburg, Russia in 1963. And it has since been used as a pharmaceutical used to treat PTSD, anxiety, depression, insomnia, alcoholism and other neurological disorders.

GABA’s role is to keep glutamate, the primary excitatory neurotransmitter, from overwhelming you. Too much glutamate can cause a seizure, and too little (or too much) GABA can put you in a coma. A healthy brain maintains a critical balance of GABA and glutamate within the central nervous system.

GABA acts like a “brake” on neuron circuits during stress. Low GABA levels can result in anxiety, insomnia, poor mood and restlessness.

Clinical studies show that boosting GABA with a supplement like Phenibut relieves anxiety, stress, and boosts the production of alpha brain waves.[i] If GABA is optimized in your brain you’ll feel focused, relaxed and stress-free.

Phenibut helps:

  • Balance mood. Phenibut has an inhibitory effect on overly stimulated neurons because it raises GABA levels in your brain. Low GABA levels lead to anxiety, depression and insomnia. GABA helps restore that balance. Promoting a more positive mood which improves focus and relaxation.[ii]
  • Boost Human Growth Hormone. Bodybuilders and athletes use Phenibut before resistance training. Studies show by raising GABA levels, you can boost blood levels of Human Growth Hormone.[iii] Promoting greater recovery support and lean muscle growth.
  • Neurotransmitters. Phenibut stimulates dopamine receptors, and antagonizes beta-phenethylamine (PEA).[iv] Dopamine aids in memory formation, attention, focus, and cognition. PEA increases the action of dopamine, norepinephrine, acetylcholine and serotonin. It’s partly behind the overstimulation that causes irritability, restlessness, and agitation that could be caused by too much dopamine and norepinephrine. Phenibut can counteract this affect giving you a cognition boost without the negatives.[v]

Overview

Phenibut (β-Phenyl-GABA, β-phenyl-γ-aminobutyric acid, Noofen, Citrocard) is derived from the inhibitory neurotransmitter GABA. The addition of a phenyl ring allows Phenibut to cross the blood-brain barrier. And the reason why neurohackers prefer Phenibut when the goal is to raise GABA levels in the brain.

Phenibut chemical structure
Phenibut

GABA (gamma-aminobutyric acid) is the major inhibitory or relaxing neurotransmitter in your brain.[vi] GABA’s primary role is to keep the major excitatory neurotransmitter glutamate in check.

GABA is naturally synthesized in your brain from glutamate. It’s estimated that 40% of the synapses in the human brain work with GABA and therefore have GABA receptors.

So when using Phenibut to boost GABA, you enhance normal sleep cycles, and improve blood pressure. GABA even stimulates the pituitary gland to secrete Human Growth Hormone. And helps produce endorphins that make you feel good after a workout or sex.

Soon after Phenibut was discovered in St. Petersburg, Russia, it was being prescribed by doctors to lower stress and anxiety, treat PTSD and insomnia.

Phenibut was included in the medical kit for Russian astronauts on the Soyuz-19 and Salyut-4 missions as a ‘tranquilizer’.[vii] Because Russian scientists found that Phenibut is one of the only tranquilizer and nootropic drug options that lowers stress levels without negatively affecting performance.

As a nootropic, when you use Phenibut to normalize GABA levels you’ll experience a reduction in anxiety, insomnia, nervousness, restlessness and stress.

Phenibut can be a more natural, safer alternative to Benzodiazepine drugs like Valium and Xanax. These pharmaceuticals work by increasing GABA receptor sensitivity.[viii]

Phenibut relieves anxiety

How does Phenibut work in the Brain?

Phenibut helps brain health and function in several ways. But two in particular stand out.

  1. Phenibut boosts GABA in the brain. Phenibut is a derivative of GABA. And easily crosses the blood-brain barrier. GABA on its own cannot cross this barrier unless paired with a dedicated carrier.[ix]

GABA works by preventing neural signaling associated with anxiety from reaching other neurons. It does this by attaching to the receptors that would otherwise excite those neurons. Over-stimulating neurons in certain areas of your brain is what causes anxiety-related symptoms.

The majority of studies on Phenibut have been conducted in Russia. And most studies have been done with animals. In this study using rabbits, scientists looked at anxiety behaviors and how they were effected by Phenibut.

They exposed the rabbits to emotional stimuli causing anxiety in the animals. Anxiety caused the rabbits to ‘freeze’ and exhibit defensive reactions. Behaviors very similar to what happens in humans when they’re under stress.

When the rabbits were administered Phenibut, the anxiety-caused reactions of defensiveness and passive reactions (freezing) decreased to normal behavior.[x]

  1. GABA changes brain waves. Using Phenibut as a nootropic helps increase GABA levels in your brain. And we know that GABA helps decrease Beta brain waves and increase Alpha brain waves.[xi]

Beta brain waves are important for attention, alertness, concentration and developing memories. But excess levels of concentration, particularly during stress, can lead to anxiety, depression, insomnia and more stress.

When you are in an alert state, both Alpha and Beta brain waves can be stimulated. But the type of alertness will determine which brain wave is produced.

Alertness during an Alpha wave state is associated with a relaxed state. And a stressed alert state produces a Beta wave. But an excess of Beta brain waves contributes to a variety of nervous disorders including anxiety and stress.

Most of the clinical studies available done with humans use GABA supplementation rather than Phenibut. But the outcome of using GABA could be applied to using Phenibut to increase GABA levels in the brain. Phenibut crosses the blood-brain barrier more effectively than GABA.

In this study, researchers investigated using GABA on relaxation and immunity during stress in humans. They evaluated the effect on 13 subjects of GABA intake on brain waves.

An electroencephalogram (EEG) was used to measure brain waves after subjects took water only, GABA or L-Theanine. 60 minutes after administration, the study showed that GABA significantly increased Alpha waves and decreased Beta waves compared to water or L-Theanine.

The researchers concluded that raising brain levels of GABA induced relaxation and diminished anxiety.[xii] And you raise brain levels of GABA effectively when supplementing with Phenibut.

Phenibut boosts alpha brain waves for alert relaxation

How things go bad

Low levels of GABA are associated with a variety of health problems.

↑ Anxiety[xiii], panic attacks, stress, PTSD, and insomnia

↑ Muscle spasms, hypertension, convulsion, Tourette’s Syndrome and epilepsy

↑ Dry skin and wrinkles

↑ Poor digestion, bloating, flatulence, and constipation

When your neurotransmitters, including GABA, are in balance, you feel motivated, productive and energetic. And you feel calm and relaxed during downtime.

When GABA levels are low you feel filled with dread, you’re constantly worried, you have racing thoughts, and you’re frequently late and disorganized.[xiv]

Many people in this GABA-slump resort to high carbohydrate foods, and drugs or alcohol to relax.

Phenibut benefits

Phenibut to relieve PTSDPhenibut is an analogue of GABA. The addition of a phenyl ring allows Phenibut to cross the blood-brain barrier much more easily than GABA taken as a supplement.

We need adequate GABA levels in our brain because it’s an inhibitory neurotransmitter. When we raise GABA levels by supplementing with Phenibut, we help keep glutamate in check.

Glutamate is your body’s most abundant excitatory neurotransmitter. Which is responsible for attention span, brain energy, learning ability, memory, and staying awake.

So GABA is calming and glutamate is stimulating. And they must be in balance with each other for optimal cognitive health.

An imbalance of these two neurotransmitters can cause fibromyalgia, chronic fatigue syndrome, poor memory and cognition, anxiety and depression.

But when these two neurotransmitters work together efficiently, you feel relaxed with no stress or feelings of anxiety. And you get a more restful night’s sleep.

Adding Phenibut to your nootropic stack can help bring GABA and glutamate back into balance.

How does Phenibut feel?

When you balance GABA levels in your brain, you feel relaxed and calm. But many neurohackers who try using GABA as a supplement don’t feel the effects. Because the GABA molecule is too large to cross the blood-brain barrier.[xv]Phenibut improves sex

Note: If you do feel the calming effects of supplementing with GABA within a ½ hour of taking it, it may mean you have a “leaky” blood-brain barrier. Not a good thing.[xvi] Because if GABA can get through, all kinds of nasty stuff can get through too. Including toxins, undigested food particles and anything else in your blood stream that shouldn’t be in your brain.

See my article on how to fix a “leaky” blood-brain barrier here: How to Heal a Leaky Blood-Brain Barrier

But here were talking about increasing our GABA levels using Phenibut. Neurohackers report that adding Phenibut to their stack relieves anxiety, there is less stress and they feel more relaxed.

In fact, some say it’s the best anti-anxiety ‘medication’ they’ve ever used. Including some well known pharmaceuticals (i.e. Clonazepam, Diazepam, Alprazolam) used to treat anxiety. With none of the nasty side effects that come with prescription meds.

Social functions could get some help with Phenibut. You could feel less inhibited, speak freely and feel more confident.

Others report that Phenibut boosts sex drive, and for men it helps control ejaculation. And it helps for a better night’s sleep.

Athletes report that Phenibut goes well with a workout. Because Phenibut has been shown to boost Human Growth Hormone. You’ll be able to work out with less fatigue, energy levels will go up, muscles won’t be as sore and recovery could be faster.

Phenibut takes 2 – 4 hours before you begin to feel its effects. A strong word of caution: do not increase the dose or take additional Phenibut if you think things are not happening fast enough!  Wait at least 24 hours before taking another dose.

Phenibut Clinical Research

GABA was identified as a neurotransmitter several decades ago. And there had been a lot of research on GABA published since. But most of it is focused on how GABA works. And the drugs and chemicals which affect its action.

There is very little research available on using GABA as a supplement. Likely because most scientists believe that GABA taken as a supplement will not cross the blood-brain barrier.

And there is even less research available on using Phenibut. Particularly in humans. Most of the clinical trials have been done in Russia and were done with animals.

Here we talk about how GABA can affect your cognition and overall health. This research supports the idea that using Phenibut to raise GABA levels can have a profound effect on your quality of life.

GABA Increases Human Growth Hormone

Bodybuilders and athletes use Phenibut or even GABA to help repair and build muscle. And there are several studies supporting the notion that GABA increases Human Growth Hormone.

In one study, researchers worked with 19 subjects who were given a single oral dose of 5 grams of GABA. 18 subjects were given a placebo during this trial. 3 hours after the administration of GABA, blood samples were taken. The team reported that “GABA caused a significant elevation of plasma growth hormone levels”.[xvii]

GABA helps Reduce Insomnia

A Los Angeles study conducted a randomized, double-blind, placebo controlled trial with 18 patients with sleep disorders. The patients received either a placebo, or Gabadone (a combination of GABA and 5-hydroxytryptophan).

The difference between the two groups of sleep-deprived patients was significant. The Gabadone group fell asleep faster, stayed asleep longer, and had a better quality of sleep than the placebo group.[xviii]

Neurohackers consistently report a similar effect on sleep quality when using Phenibut.

Recommended Phenibut Dosage

Phenibut recommended dosageThe recommended daily starting dosage of Phenibut is 200 – 300 mg. for a relaxation or calming effect. Give it 2 – 4 hours before it starts to kick in. Your Phenibut dose should be taken on an empty stomach.

More experienced Phenibut users go with high doses of up to 1 – 1 ½ grams per dose. And up to 3-times per week.

Since you can quickly build up a tolerance to Phenibut dosing less often is preferred. Many advise keeping Phenibut use to once or twice per week with almost no side effects and no hangover the next day.

Phenibut can be very addictive for some people and the withdrawal symptoms from continuous use is particularly nasty. So if you’re going to try Phenibut make sure you follow dosage recommendations to prevent Phenibut overdose.

Phenibut Side Effects

Phenibut is considered safe when taken in normal recommended doses.

Bodybuilders who use much higher doses of Phenibut do report experiencing flushing, tingling, a spike in heart rate and blood pressure, and anxiety.

You can build up tolerance to Phenibut quickly. And if you have an addictive personality you should avoid using Phenibut.

Most neurohackers suggest cycling Phenibut. Using recommended doses for 4 or 5 days and taking a few days off. Others suggest only using Phenibut once per week.

You’ll have to find out what works for you if you decide to try Phenibut. And expect to have a rough ride at first. Too much and the withdrawal can be nasty. Phenibut withdrawal symptoms can occur even with short-term therapeutic use.

While it is considered legal to use Phenibut as a nutritional supplement in the United States, it is highly advised that you do so with caution. It is technically not a controlled substance, but it is dangerous for those taking Phenibut with other substances.

For example, you are strongly advised not to combine Phenibut with alcohol. And absolutely DO NOT combine Phenibut with benzodiazepines. Or you could put yourself into a coma that you may not come out of. Avoid anything that touches or increases GABA when using Phenibut.

Where to buy Phenibut

Phenibut as a supplement is available in tablet, capsule and powder. Scientists have shown that Phenibut easily crosses the blood-brain barrier.

Phenibut is an analogue of GABA developed in Russia, and it increases levels of GABA in your brain. While some report that Phenibut causes drowsiness and fatigue, it’s a much safer way to boost GABA than with benzodiazepines. But do NOT combine either benzos or any drug that raises GABA with Phenibut because you could put yourself into a coma.

I recommend Cosmic Nootropic – Phenibut.

Nootropics Expert Recommendation

Phenibut 200 – 300 mg per day.

Nootropics Expert Tested and ApprovedI recommend using Phenibut (with caution) as a nootropic supplement if you’re feeling anxiety or stress. And to calm or keep in check the stimulatory effects of some nootropics.

Your body does make GABA on its own from glutamate in your brain. Most healthy people have an adequate supply of GABA. But if you’re dealing with anxiety or stress and need some extra help in calming things down, Phenibut can help.

Phenibut is particularly helpful if you’re dealing with Post Traumatic Stress Disorder (PTSD). I’ve seen reports by combat veterans who say that Phenibut worked far better than any prescription anti-anxiety med.

I suggest trying a Phenibut dietary supplements first at a dose of 200 – 300 mg. Phenibut can be a powerful method of boosting GABA levels in your brain. But it also has addictive potential especially if you’re prone to addiction.

Phenibut takes 2 – 4 hours to take effect in your body. Do not yield to temptation and take more just because you’re not feeling anything. Sometimes the beneficial effects of Phenibut are not felt until the next day.

Cycle your use of Phenibut to avoid tolerance and side effects. Your sweet spot could be every 2nd or 3rd day. Or even just once a week. Find out what works best for you.

The ‘hangover’ from abusing Phenibut is particularly nasty. You should be able to avoid these side effects by keeping doses low. And limiting the days you use Phenibut.

You can safely work your way up to 1,500 mg of Phenibut per day on the day that you dose. Some athletes go as high as 3,000 mg. But for nootropic use, a higher dose is not necessary or recommended.

I recommend Cosmic Nootropic – Phenibut.

As an Amazon Associate I earn from qualifying purchases. This post may also contain other affiliate links and I will be compensated if you make a purchase after clicking on my links.

[i] Nemeroff C.B. “The role of GABA in the pathophysiology and treatment of anxiety disorders.” Psychopharmacology Bulletin. 2003;37(4):133-46. (source)

[ii] Lapin I. “Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug.” CNS Drug Revues. 2001 Winter;7(4):471-81. (source)

[iii] Cavagnini F., Benetti G., Invitti C., Ramella G., Pinto M., Lazza M., Dubini A., Marelli A., Müller E.E. “Effect of gamma-aminobutyric acid on growth hormone and prolactin secretion in man: influence of pimozide and domperidone.” Journal of Clinical Endocrinology and Metabolism. 1980 Oct;51(4):789-92. (source)

[iv] Lapin I. “Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug.” CNS Drug Revues. 2001 Winter;7(4):471-81. (source)

[v] Anden N.E., Wachtel H. “Biochemical Effects of Baclofen (β-Parachlorophenyl-GABA) on the Dopamine and the Noradrenaline in the Rat Brain” Acta Pharmacologica et Toxicologica Volume 40, Issue 2, pages 310–320, February 1977 (source)

[vi] Petroff O.A. “GABA and glutamate in the human brain.”Neuroscientist 2002 Dec;8(6):562-73. (source)

[vii] Neumyvakin I.P., Krupina T.N., Polevoĭ L.G., Semeĭkina L.A. “[Principles for making up pharmaceutical kits to supply cosmonauts with drug packs].” in Russian Kosm Biol Aviakosm Med. 1978 May-Jun;12(3):27-31. (source)

[viii] “HOW DRUGS AFFECT NEUROTRANSMITTERS” McGill UniversityCanada (source)

[ix] Kuriyama K., Sze P.Y. “Blood-brain barrier to H3-γ-aminobutyric acid in normal and amino oxyacetic acid-treated animals”Neuropharmacology Volume 10, Issue 1, January 1971, Pages 103–108 (source)

[x] Ziablitseva E.A., Pavlova I.V. “[Effect of GABA receptor agonist phenibut on behavior and respiration of rabbits in the negative emotional situation].” Zh Vyssh Nerv Deiat Im I P Pavlova. 2007 Jul-Aug;57(4):479-88. (source)

[xi] Abdou A.M., Higashiguchi S., Horie K., Kim M., Hatta H, Yokogoshi H. “Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.” Biofactors. 2006;26(3):201-8. (source)

[xii] Abdou A.M., Higashiguchi S., Horie K., Kim M., Hatta H, Yokogoshi H. “Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.” Biofactors. 2006;26(3):201-8. (source)

[xiii] Enna S.J. “Role of gamma-aminobutyric acid in anxiety.”Psychopathology. 1984;17 Suppl 1:15-24. (source)

[xiv] Struzyńska L., Sulkowski G. “Relationships between glutamine, glutamate, and GABA in nerve endings under Pb-toxicity conditions.”Journal of Inorganic Biochemistry. 2004 Jun;98(6):951-8. (source)

[xv] Kuriyama K., Sze P.Y. “Blood-brain barrier to H3-γ-aminobutyric acid in normal and amino oxyacetic acid-treated animals”Neuropharmacology Volume 10, Issue 1, January 1971, Pages 103–108 (source)

[xvi] Montagne A., et. Al. “Blood-brain barrier breakdown in the aging human hippocampus.” Neuron 2015 Jan 21;85(2):296-302 (source)

[xvii] Cavagnini F., Invitti C., Pinto M., Maraschini C., Di Landro A., Dubini A., Marelli A. “Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man.” Acta Endocrinologica (Copenhagen). 1980 Feb;93(2):149-54. (source).

[xviii] Shell W., Bullias D., Charuvastra E., May LA., Silver D.S. “A randomized, placebo-controlled trial of an amino acid preparation on timing and quality of sleep.” American Journal of Therapeutics. 2010 Mar-Apr;17(2):133-9. (source)

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Join The Discussion - 155 comments

Tom
November 10, 2019

Hi David, Thanks for this article. I thought it was informative on several fronts however I must say I think you should have emphasized the dangers around this GABA analogue as we know the risks with regards to the mental well being of patients in short term and protracted withdrawal. I don’t think the withdrawal was just “nasty” I would add it that it was utterly life altering. I was unable to get over the hump of just two days and began what I think may have been a kindling process. My anxiety and depression got so bad that I simply locked myself in my apartment for two weeks and used alcohol medicinally to just keep my head above water. Benzo’s will not work in relieving that anxiety as they are working on different receptors. Luckily I was able to get through it responsibly but it was not good 🙂 This is just one of issues with Phenibut as I could go on and on. I actually think its really dangerous. That said I’m not sure I’d advocate removing it. Anyway One year on and I still battle deep depression. I believe Phenibut downregulated my Dopamine capacity. On this I am not an expert and was wondering if you are? It had, for me, a very direct and stimulating effect. I can tell this depression is Dopamine related…. Its the can’t get moving, can’t get out of bed…I just know my brain rather well at this point but I don’t know how to restore the system? Do you have any inisght? L-tyrosine, of course….but what else? Any help would be appreciated

    David Tomen
    November 11, 2019

    Tom, I agree that Phenibut can be dangerous. But it’s here and I’ve reviewed it because you can buy it over-the-counter and it would be irresponsible of me not to talk about it. I do appreciate your input and telling us how it affected you. This is important for people to know and why I never recommend it when we have so many other great options.

    If you think dopamine is your problem I’d start with 500 mg L-Tyrosine 3-times per day and no later than 4 PM. You can also try Mucuna Pruriens. Dosage on that varies because it comes in different strength extracts of L-DOPA.

    I also suggest supporting dopamine receptors. Aniracetam (https://nootropicsexpert.com/aniracetam/) works in part by up-regulating dopamine D2 and D3 receptors. Then use something for boosting BDNF which will help repair neurons, dendrites, axons and synapses. Ashwagandha is one option. Lion’s Mane Mushroom is another.

JQ
November 7, 2019

I’m trying to see how this is better than xanax. It is addictive with a nasty hangover. It says that it doesn’t have the negative effects of Rx drugs but that seems worse than xanax to me. ?

    David Tomen
    November 7, 2019

    JQ, the side effects of Phenibut can be particularly nasty but they are temporary. The side effects from benzos like Xanax are in a class of their own. And people suffer the side effects even years after quitting the drug.

      Tom
      December 6, 2019

      Oh boy, the innocence of that comparison. I don’t mean to make light of your comment JQ. I’ve already stated I believe that Phenibut withdrawal is much more serious than currently accepted. Benzodiazepine withdrawal is an exquisite kind of hell that can last for quite a long time. I’m almost hesitant to leave that comment in case anyone going through benzo withdrawal reads it as I know how fragile things can be. There is nothing in this world comprabale to benzo withdrawal. No kind of opiate or anything else can hold a candle to that taste of hell. Phenibut withdrawal is real and its hard. I’m going on a year now where I still have a current of fear and terror that is indicitive of GABA withdrawal. But I know that Benzo withdrawal is essentially the first week of Phenibut withdrawal but it can not be a week but rather a year. People going through that have REAL strength

Malik Gilmore
November 7, 2019

Will GABA have the same effect as Phenibut , if I have a leaky blood brain barrier . I’m working on repairing it now , but I think I could use It to my “advantage” right now if I use GABA to calm anxiety . I’m looking to calm my brain down for when I enter a social situation . Any dosage recommendations?

John
October 20, 2019

Hi David,

I have a similar story to you in some areas. I was diagnosed with ADHD at age 12, suffered for a long time with adhd symptoms, anxiety, depression, motivation, concentration, brain fog, fatigue, mood swings, irritability etc etc long list! I’ve been fortunate enough to scrape by and complete schooling almost through my second bachelors degree and high pressured work. I’m seeing big side effects with pharmaceuticals I’m prescribed for adhd and anxiety/depression. I’m off them now and I absolutely need one hell of a stack to get back on top. I can’t seem to find an email address for you. Could you please contact me I really need help designing my stack there’s sooo much information and supplements here and I obviously can’t and shouldn’t take all of them but I will take as many as I can to optimise my brain and feel happy and productive again. My life demands mental clarity and control and if I don’t deal with this ASAP I’ll have some very bad outcomes. So much appreciated if you can reach out as soon as you receive this and call or email me and help me with sources and designing my stack. I see great potential with your page I just can’t seem to decipher what would be the best stack and how to source it please contact me ASAP Thankyou so much!

Richard
October 8, 2019

Hello David,

I realize this might not be the right place and that you’re not a doctor. But doctors don’t know anything about phenibut; literally – I’m sorry I can’t help you with that’. Anyways; It hasn’t been that long and I’m tapering. So far so good. Is there anything that can assist a taper? Fasoracetam has come up in research. NAC aswell. Kava Kava. Baclofen… slowly cross tapering. Memantine. I think they all might help to some degree. But I think simple is better. I have the feeling the kava kava is helping a lot. It’s my mistake, and I knew where I got myself into. It was work-related. A do or die situation. I felt I did what I had to do and I’d face the consequences later; which is now. I’m pretty good at tapering. That’s a little plus. And agmatine has helped a lot to bring it down fast. I’m looking for the bottom dose and I’ll take it from there. Nice and slowly. But any advice would be more than welcome. I’m sorry if this is against the rules:). I can get baclofen from a doctor; If I explain what’s going on – but working closely on a taper; that won’t happen. So I’ll have to figure it out myself. And I will.

Thank you.
Kind regards,
Richard

Ivan
September 11, 2019

Good morning dear David, two months ago, for 2 weeks, I took phenibut 250mg as sold in Ukraine (Bifren is the name) and i slept very good, and no side effects.

Now, after 2 months, i have ordered the equivalent on Amazon, “Vita-Go Sports Phen GABA 250mg”

I took the first pill of this new box last night. After i took the pill, my back started aching me. I slept very deep, despite my back was bothering me. This morning, arrived in office, i could not even stand nor walk for the pain. I had to take pain killers.

Did anyone else report this strong side effect?

Both the versions contain 250mg of B-phenyl-γ-aminobutyric acid. The other ingredients are more or less the same (magnesium stearate, silicon dioxide, and something else that i can’t actually decipher as my russian is still not so good).

Would you have any advice?

To be noted also, that the effects i had with the phenibut i took the first time, were more mild. Last night i felt the effects stronger. But i noticed that the ukrainian box i took two months ago, was about to expire (October 2019). Maybe that’s the reason.

I am thinking of trying to take half of dose next time.

Many thanks,
Ivan

    David Tomen
    September 11, 2019

    Ivan, Phenibut may cause drowsiness and fatigue but certainly NOT pain. It sounds like you got a bad supplement that could be tainted with another undisclosed ingredient. I suggest contacting the manufacturer and asking for a “Certificate of Analysis” for the batch that you bought from them. If they can’t or are not willing to provide it then I recommending returning the product for a refund.

Lisa-Marie
August 1, 2019

Hello David,

in one article you mentionned that there is a way to improve a ‘leaky’ Brain Blood Barrier, I could not find the article about it.

thanks!! wonderful work 🙂

Yersinia
July 31, 2019

Dear David,

Thanks for sharing your knowledge, you have amazing website and best nootropics channel on YT!

Almost every time I take phenibut, after 3-4 h I seem to get a headache that lasts about an hour. I do take Alpha GPC daily. For the record I just recently stasrted experimenting with phenibut and I take it only 2-3 times a week maximum (500mg each time). Do you happen to know why I’m getting this headaches from phenibut? I couldn’t find it anywhere, hope you can help!

Thank you so much and keep up the good work.

    David Tomen
    July 31, 2019

    Yersinia, the only thing I can think of is your Phenibut dosage is too high. Try cutting the dosage in half and see if that helps.

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