I often get emails from Nootropics Expert readers asking me what my favorite nootropic stack is. And what I use every day. This post is a detailed response to that question.
NOTE: This review has been updated to reflect the changes to the Mind Lab Pro® formula which was refreshed in early 2017.
Mind Lab Pro® is by far the best nootropic stack I’ve ever used. And I’ve tried a lot of them over the last 12 years. Including ready-made stacks from the local vitamin shop to many of the well-known stacks found online.
Nearly 13 years ago, I was diagnosed with Adult ADD and my doctor put me on Ritalin. It was like the lights suddenly came on in my brain. And for the first time in my life I could concentrate and focus.
Up to then, I took my brain for granted. And hadn’t considered that the health of my brain affected every single aspect of my life.
That point was also the beginning of a journey into how my brain worked. What was wrong, and an earnest search on how to fix it. I’ve read thousands of threads on Reddit, Longecity and nootropic blogs in this search for the ultimate nootropic stack.
Table of Contents
My Nootropic Stack Criteria
As this deep dive into neuroscience took shape, I started to develop a map of sorts on what my options were. Areas that I could fix on my own. And other areas that could be boosted and tweaked to get the most out of this amazingly complex organ in my head.
This is the list of cognitive improvements I eventually came up with:
- increase memory and recall
- eliminate brain fog
- ramp up motivation
- boost personal confidence
- help with concentration
- magnify my ability to learn and retain
- focus easily
- maintain a better mood – tone down depression
- improve vocabulary – words come easily
- reduce stress levels
- have better coordination
- improve sleep
It soon became clear that no prescription drug on earth could help achieve the results I was looking for. A completely optimized brain firing on all cylinders.
So I turned to natural supplements and started experimenting. Through trial and error things started to come together. My memory and recall got better. Confidence levels improved and I was in a better mood. Stress levels went down. And a better night’s sleep was finally within reach.
Anyone who has been down this path of brain optimization knows the expense and work involved. I’ve spent thousands upon thousands of dollars on supplements. Trial and error with different compounds. Buying ready-made stacks that promised a lot. But always fell short in some way.
Eventually I started buying nootropic supplements in bulk powder form and began making my own capsules. Still a costly way to boost my brain power but entirely worth the effort and expense. Both in my career and relationships with those I love.
Discovering Mind Lab Pro
But I was always on the lookout for the ideal nootropic stack that could help replace some of the many supplements I was taking. And in late 2015 I finally found it in Mind Lab Pro.
I’ve been using Mind Lab Pro every day since then. And haven’t found another premade nootropic stack that comes anywhere close to what this stack can do.
Who Makes Mind Lab Pro?
Mind Lab Pro is a premium nootropic stack developed by Opti Nutra® in the U.K. The company promotes Mind Lab Pro as “the first Universal Nootropic” stack that boosts all aspects of cognition in all types of people.
This nootropic stack can be used by students, athletes, competitors in sports and games, working professionals and even those over 55.
So how can one stack promise so much in just two capsules per day? Let’s dig into the ingredients to see what they do in the brain, and how they work.
(Note that every ingredient in Mind Lab Pro listed here links through to a full review of each nootropic on Nootropics Expert. You’ll get more detail on the history, clinical studies, dosage recommendations, side effects and forms available).
Mind Lab Pro Ingredients
This is the formula that the team at Opti Nutra Ltd. created for Mind Lab Pro that works so well for me. And thousands of other neurohackers around the world.
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- Bacopa Monnieri 150 mg standardized to 45% active bacosides cuts back learning time, and improves memory including recall.[i]
The active bacosides in Bacopa protects brain cells from free radicals which prevents cell damage and death. Bacopa also boosts acetylcholine, GABA and serotonin – all tied to focus, clear memory and better mood. Bacopa even helps boost cerebral circulation.
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- Citicoline as Cognizin® 250 mg enhances attention, concentration, memory, logical reasoning, learning and focus.[ii]
Citicoline helps synthesize phosphatidylcholine (PC), a major phospholipid found in brain cell membranes. And supports the neurotransmitter acetylcholine while providing antioxidant activity.
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- Phosphatidylserine (PS) as Sharp PS® Green 100 mg improves memory and attention, increases cognitive processing speed, and accuracy.[iii]PS is a phospholipid making up 15% of brain cell membranes. Maintaining cellular fluidity, optimizing neuroreceptors and promoting acetylcholine and dopamine.
PS even increases nerve growth factor to help neurogenesis, cell maintenance and repair.
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- Lion’s Mane Mushroom (full-spectrum) 500 mg is effective in improving memory, neuron repair,[iv] liver detox, and regulating blood sugar and cholesterol levels.
Lion’s Mane is the only mushroom that supports brain health. The active hericenones and erinacines stimulates Nerve Growth Factor which helps neurogenesis, and myelin axon sheath synthesis. Improving neuroplasticity which is involved in memory formation, and keeping cell membranes healthy.
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- Rhodiola Rosea 50 mg standardized to 3% rosavins and 1% salidrosides improves mental performance under stress, and enhances mood.[v]
Rhodiola boosts mood by influencing norepinephrine, serotonin and the feel-good opioids like beta-endorphins levels in your brain. It helps neurogenesis, activates the synthesis of ATP, and reduces the inflammatory C-reactive protein in your brain.
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- L-Theanine 100 mg as Suntheanine® improves focus[vi], sleep, immune system strength, and blood pressure control.L-Theanine increases alpha brain waves which are associated with relaxation and enhanced creativity.
It settles excitatory neurotransmitters while promoting calming neurotransmitters like serotonin and GABA. Sharpening attention, alertness and focus that help creative problem solving, learning and studying.
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- N-Acetyl L-Tyrosine (NALT) 175 mg is an amino acid critical for the synthesis of catecholamine neurotransmitters dopamine, epinephrine and norepinephrine in your brain.Boosting these catecholamines helps improve cognition, mood, and memory.
NALT has been shown to promote working memory when multitasking.[vii] And NALT helps optimize mental performance under high stress, fatigue and sleep deprivation.
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- Maritime Pine Bark Extract 75 mg standardized for a minimum of 95% proanthocyanidins. This extract helps increase levels of nitric oxide which helps dilate blood vessels. Delivering more oxygen and glucose to brain cells for more energy, better learning and memory, enhanced focus and elevated mood.
Pine Bark Extract is one the most potent antioxidants ever discovered. Scavenging free radicals to protect neurons from oxidative damage.
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- Vitamin B6 2.5 mg supplied in the bio-identical form of OptiNutra’s NutriGenesis® vitamins which is critical for the synthesis of the major neurotransmitters dopamine, GABA, norepinephrine and serotonin. Which influence mood, melatonin, and helps regulate your body clock.[x]
B6 also helps protect your brain from excess homocysteine that can damage blood vessel linings. And B6 helps form myelin which is the protective sheath that surrounds axons in your brain and body.
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- Vitamin B9 100 mcg in the bio-identical form of OptiNutra’s NutriGenesis® vitamins. This vitamin participates in one-carbon transfers for the synthesis of DNA and RNA. And works with the other two B-Vitamins in this stack help regulate homocysteine levels.
Folate is also involved in gene expression, amino acid synthesis, and myelin synthesis and repair.
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- Vitamin B12 7.5 mcg in the bio-identical form of OptiNutra’s NutriGenesis® vitamins which is required to regulate homocysteine levels in your brain and body.
B12 is also a cofactor in the synthesis of the major neurotransmitters dopamine, GABA, norepinephrine and serotonin. Low levels of Vitamin B12 has been linked to poor mood and cognition leading to cognitive decline at any age.[xi]
One of the things that stands out in this nootropic stack is Opti Nutra chooses to use their proprietary NutriGenesis® form of vitamins. Which are nature-identical to ensure these B-Vitamins are completely absorbed and used by your body and brain.
Mind Lab Pro Dosage
The amount of each ingredient listed is for Opti Nutra’s recommended 2-capsules per day. You can safely increase your dose to 4-capsules per day. 2 in the morning and 2 early afternoon.
Like every nootropic, it’s always better to start low and see how your body and brain react before increasing your dosage.
Synergy of Nootropic Ingredients is Key
The key to making this nootropic stack work is two-fold:
- the exact amount required for optimal performance from each ingredient
- synergy or how they work together and complement each other for maximum results.
This idea of “synergy” is a big deal when putting together a nootropic stack. While each nootropic on its own could call for a higher dosage, when combined they work together better in the brain at smaller doses. But more on these doses in a minute.
Just Say “No” to Proprietary Formulas
One thing that irks me is the way many nootropic manufactures ‘hide’ the exact amount of each ingredient in their stack. They call it their “proprietary formula”.
But Opti Nutra chooses to disclose exact amounts on their packaging. So I know exactly what I’m taking. For me, this shows respect for me as a customer. Then I have the option of upping doses of certain nootropics that are unique to my condition and state of health.
For example, I’m Adult ADD and continue to use 20 mg of Ritalin twice a day. Ritalin works by blocking the reuptake and degradation of dopamine in my brain. Making more dopamine available to help my focus and concentration.
The problem for me, and for many with ADD and ADHD as we get older is there’s not enough dopamine in my brain to start with.
Mind Lab Pro addresses this lack of dopamine with NALT. But in my case, the dose of NALT is too low. So I add 800 mg of NALT and 1,000 mg of ALCAR each time I take my Ritalin dose.
The result has been greater efficacy of Ritalin. I’ve never had to increase my dose of Ritalin due to tolerance. And at the end of my day, I don’t experience a stimulant ‘crash’ which is common when using these types of stimulants.
Do I consider this a ‘con’ for Mind Lab Pro? Absolutely not. Because while I need extra dopamine and acetylcholine in my brain, you may not. Unless you’re dealing with something like ADHD.
And I know exactly how much NALT and ALCAR to add to this stack because Opti Nutra tells me how much they are supplying in their stack. There is no guessing.
How Mind Lab Pro Works in Real Life
I love this nootropic stack. Two capsules in the morning with a tablespoon of organic unrefined coconut oil. And it launches my day. In my case with ADD and being hypothyroid, I take another two capsules at noon with coconut oil.
I also use 1,000 mg of DHA in the morning. Along with Aniracetam and Sulbutiamine. Since starting Mind Lab Pro my productivity has increased. My mood is better. Focusing on several projects is not a problem. Work seems to go faster. And I get more done in less time.
Everything just seems better. And life flows.
Mind Lab Pro is Impressive value
One of the things I’ve learned over the years of working with nootropics is it’s not cheap. In fact, taking each nootropic on its own in my case, can add up to a few hundred dollars per month.
But using Mind Lab Pro has dramatically reduced my nootropic budget. Here’s a breakdown of how much each of these nootropics would cost if purchased individually.
Note: These prices are from Amazon.com here in the USA at the time I write this. They’re usually competitive with other retailers online, and brick & mortar stores. Prices could be different in your part of the world, or when you read this.
Bacopa Monnieri (45% bacosides) 250 mg – 90 capsules $14.99
Citicoline (Cognizin®) 250 mg – 60 capsules $20.38
Phosphatidylserine (PS) (Sharp PS® Green) 100 mg – 120 capsules $48.97
Lion’s Mane Mushroom (full-spectrum) 500 mg – 60 capsules $8.99
Rhodiola Rosea (3% rosavins, 1% salidrosides) 250 mg – 60 capsules $7.86
L-Theanine (Suntheanine®) 100 mg – 60 capsules $11.49
N-Acetyl-L-Tyrosine (NALT) 350 mg – 120 capsules $12.29
Pine Bark Extract (95% proanthocyanidins ) 100 mg – 300 capsules $18.52
Vitamin B6 (P-5-P) 25 mg – 100 capsules $17.95
Vitamin B9 (folate) 400 mcg – 90 capsules $7.21
Vitamin B12 (Methylcobalamin) 1 mg – 60 capsules $18.95
The total of each of these evidence-backed nootropics when purchased individually comes out to $187.60.
Now I realize that the dosages in this comparison are often higher when used individually. The quantities per bottle are often higher than a monthly supply. And I’ve included supplements packed in vegetarian capsules which are often priced a little higher than regular capsules.
Sure, I could re-calculate each of the comparison prices by counting capsules per bottle to figure out the exact monthly dose.
Adjusting the price per capsule accordingly.
But my point here is the cost of buying each of these nootropics individually will be higher. Much higher than what Opti Nutra charges for Mind Lab Pro.
Mind Lab Pro for a 30-day supply if you take the recommended 2 capsules per day is only $65.00 (+ shipping & handling).
You can also choose a 3-month supply (3 boxes) of Mind Lab Pro for $195.00 and get one box free (including free international shipping & handling). That works out to $48.75 per box.
Pros & Cons of Mind Lab Pro
Opti Nutra has taken an extra step to include NutriCaps® instead of regular vegetarian capsules in their stack. These vegan caps are made from tapioca.
Most competitors (including the nootropics listed above) use HPMC vegetarian capsules which are made from a semi-synthetic polymer.
Now, let’s look at what I think are the pros and cons of this premium nootropic stack.
Pros
- Full disclosure on the amount of each ingredient
- High quality branded ingredients (i.e. Cognizin®, Sharp PS®, NutriGenesis® vitamins, Suntheanine®)
- Vegan natural NutriCaps®
- Highly bioavailable B-Vitamins (P-5-P and methylcobalamin)
- No additives
- Organic when available, and always free of toxic heavy metals and other contaminates
- Tested prior to encapsulation for allergens, GMOs, microbes, pesticides and herbicides
- Batches are re-tested to confirm potency, purity and activity after encapsulation
- Ships in recyclable cardboard security boxes filled with biodegradable packing peanuts
- Competitively priced
Cons
- Only available on their website (more on this in a minute)
- Citicoline dose is too low if you’re using racetams
In all, I think the dosages included in Mind Lab Pro are perfect for this stack. In these dosage ranges side effects are minimized, or non-existent.
And because they fully disclose how much is in each 2-capsule dose, I have a better idea on what I need to add to this stack for my unique issues.
Nootropics Expert Recommendation
We recommend the use of Mind Lab Pro as a nootropic stack for total brain optimization.
Pricing of Mind Lab Pro is very competitive for what you get. Some on reddit.com and other blogs have commented that Opti Nutra only sells this stack from their site. And don’t offer a free trial.
I’ve been in internet marketing for many years and completely understand the hazards of offering a free trial. Especially when you’re selling a high-quality product at the best price you can to stay competitive. It doesn’t make sense to offer free trials when you back it up with a risk-free, “empty bottle”, money-back guarantee.
Opti Nutra has also decided not to offer Mind Lab Pro on Amazon.com because they don’t want this stack to appear alongside low-quality junk products. I get that. Amazon can also be a place where reviews are easily manipulated by jealous competitors.
And for anyone looking to understand the methodology that went into developing this stack, Amazon.com is not the place for extensive product descriptions.
So if you’ve been experimenting with nootropics for a while, or even considering getting into neurohacking – I recommend giving Mind Lab Pro a try.
This is the best pre-made nootropic stack I’ve ever tried. And this after nearly 10 years of trying dozens of nootropics. Both individual ingredients, and various stacks by different manufacturers.
It’s certainly not the cheapest nootropic stack on the market. But it’s not unreasonably priced either at only $65 for a month supply. You can’t put this stack together individually for less than twice or even three times what Opti Nutra charges.
And for me, Opti Nutra went the extra mile by going top notch with everything in this stack. Product and packaging quality, brand name ingredients, testing and more testing, organic when they can. Right down to using and NutriGenesis® and NutriCaps®. Touches the average person wouldn’t even notice. Now that’s cool.
If you’d like to try Mind Lab Pro, or learn more about this premium stack, please go to their website for more:
[i] Carlo Calabrese, N.D., M.P.H., William L. Gregory, Ph.D., Michael Leo, Ph.D., Dale Kraemer, Ph.D., Kerry Bone, F.N.I.M.H., F.N.H.A.A., and Barry Oken, M.D. “Effects of a Standardized Bacopa monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly: A Randomized, Double-Blind, Placebo-Controlled Trial”. Journal of Alternative and Complimentary Medicine. 2008 Jul; 14(6): 707-713 (source)
[ii] “Citicoline,” WebMD. www.webmd.com/vitamins-supplements. Retrieved November 24, 2015
[iii] “Phosphatidylserine,” WebMD. www.webmd.com/vitamins-supplements. Retrieved November 24, 2015
[iv] Wong, K.H., Naidu M., David, RP., Bakar R., Sabaratnam V., "Neuroregenerative potential of lion's mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (higher Basidiomycetes), in the treatment of peripheral nerve injury (review)" International Journal of Medicinal Mushrooms. 2012;14(5):427-46. (source)
[v] ”Rhodiola,” Life Extension Magazine. www.lifeextension.com. December 2007. Retrieved November 24, 2015.
[vi] “Theanine,” Mitchell, Terri. Life Extension Magazine. www.lifeextension.com. January 2006. Retrieved November 24, 2015.
[vii] Thomas J.R., Lockwood P.A., Singh A., Deuster P.A. “Tyrosine improves working memory in a multitasking environment.” Pharmacology, Biochemistry and Behavior. 1999 Nov;64(3):495-500. (source)
[viii] “The “Other” Resveratrol,” Johnson, Tiesha D. RN, BSN. Life Extension Magazine. www.lifeextension.com/magazine. Retrieved November 24, 2015.
[ix] “Vinpocetine,” Life Extension Magazine. www.lifeextension.com. February 2006. Retrieved November 24, 2015.
[x] “Vitamin B6,” University of Maryland Medical Center. www.umm.edu. August 5, 2015. Retrieved November 26, 2015.
[xi] Louwman M.W.J. et al “Signs of impaired cognitive function in adolescents with marginal cobalamin status” The American Journal of Clinical Nutrition September 2000 vol. 72 no. 3 762-769 (source)
Hi again, do you recommend we cycle this, Ive heard different views, do you cycle? And do we take these nootropics with food?
Arik, I do not see the need to cycle Mind Lab Pro. The amount of each ingredient in this stack is not high enough to warrant cycling. I’ve been using it daily for the last 6 years. And it works every single day.
Some of the compounds in Mind Lab Pro are fat-soluble. So you need the healthy fats in food to ensure they absorbed by your system. But I don’t bother trying to time my stack with a meal and simply use a tablespoon of unrefined coconut oil or MCT Oil each time I take my supplements. That fat ensures absorption.
Hello, i’m going to try MLP I’ve had chronic low to mild depression/anxiety for many years. By now i feel my brain is burned out : fatigue, brain fog, difficulties to focus and memorize, no motivation, tinnitus etc. I’m not, of course, expecting anything spectacular from nootropics, but would be satisfied to find something to use long term in order to support overall brain health. Some kind of “brain food” to take daily alongside multi vita, omega 3 for exemple.
So i’m going to give a shot to MLP through your link…
I have a few questions :
1) B vitamins : i already take a daily multi vitamin that contains 1,4mg B6 (100% dri), 200μg B9 (100% dri) and 3μg B12 (120% dri). Mindlab Pro also contains those same vitamins, does it make it “too much” ? I read several warnings about dangers of going too far with vitamins…
2) St John’s Wort : i take 600mg daily of a standardized extract and i plan to reach 900mg, the effects are mild but are clearly present, with no side effects. Is it safe to combine this with MLP ? Knowing that some ingredients already have an impact on serotonine, like Rhodiola for exemple. I had to abandon Rhodiola recently, i took 300mg per day (mixed with saffron) combined with St John’s Wort and i felt really tired and “brainfogded” for the next hours…
3) Fatigue : i read some comments on a nootropic forum of some folks who experienced enhanced tiredness while taking MLP. I know that these were only two people … but the lack of energy resulting from my chronic illness is very delibitating and i wouldn’t want it to be worsened… Could you tell me from your experience if there’s something to worry about ?
Thanks for your time and sorry for the bad english ! 😉
Stanislas, the duplication in B-Vitamins with Mind Lab Pro and your Multi should not be a problem. They’re definitely not in the danger zone.
Just so you know, a safer option would be a multi like the Performance Lab NutriGenesis Multi I talk about on this site. Because the vitamins and minerals are all ‘natural’ and ‘bioactive’ forms of these nutrients. Just like in MLP. There is less worry of ‘overdosing’ when using this form of nutrient because your body knows what to do with it.
It will depend on your system if you can use St. John’s wort with Mind Lab Pro. The amount of each ingredient in MLP, while very effective because they work in synergy, are dosed low enough that you may be OK with the combo. Only way to find out is to try it.
More “fatigue” from using Mind Lab Pro is highly unusual. But it is possible because it is a powerful stack. But safe for most people. I’m sure there are a very few who may experience fatigue because acetylcholine or dopamine was too high for their system. That is exactly the opposite reaction that most people experience.
If you have no serious health issues MLP may work well for you. Only way to find out is to try it. And if it doesn’t they do have a generous guarantee so there is little risk.
Hi – Based on “What I Take” link – you have both MindLab Pro as well as taking:
Alpha GPC
NALT
These are already in the MindLab Pro blend… is this not too much of a dosage?
*side crazy question – how do they get That Much into a couple capsules?
Robert, it works for me because this brain needs more dopamine and acetylcholine. That certainly is not the case for everyone.
It is surprising how much you can fit into two capsules if you don’t include any other ‘junk’ like “other ingredients”.
David,
What’s your take on combining Mind Lab Pro (and also all the other stuff on your ADHD stack) with meds like Paxil and Wellbutrin? I’m interested in trying these things you’ve listed that you take for your ADD.
I’m also curious about Ritalin. How does it compare to things like Adderall, Atomoxetine, etc? And do you have any good suggestion for a legit online ADD test? I’ve recently looked in to making an appointment with a psychiatrist, but because of COVID, they’re booked out months in to the future….
Thanks David!
Hi David!
First of all, thanks a lot for this wonderful resource! It is very well structured and contains a lot of helpful information. Your YT channel is great as well.
I am 26, IT professional without any diagnosed mental diseases, looking for ways to boost my performance. I am relatively new to nootropics. Few weeks ago I started using MLP.
My stack now is: in the morning 2 MLP capsules, one extra Lion’s Mane pill, Omega-3 from Solgar, CoQ + Magnesium from Doctors Best. In the evening I take a pill of Gaba with a pill of 5-Htp from Nowfoods.
My issue is when i take 2 MLP capsules at once, i quickly turn somewhat edgy! It feels like blood pressure in my head increases, this affect lasts for about an hour, then things turn to normal and I can see pure MLP effect. I feel like I am doing something wrong so I wanted to hear what you think on my case. May be I should split this 2 capsules with 1hour break ? Or may be I should get rid of / add something to my stack ?
The thing is when I take L-Dopa instead of MLP, for example, I do not experience any side effects.
Could you please share your thoughts ? Thank you in advance !
Yury, you are likely reacting to the N-Acetyl L-Tyrosine dose in Mind Lab Pro. I suggest splitting your dose so you take one capsule in the morning and another at noon. That way you get the benefits of everything Mind Lab Pro has to offer. And you avoid the side effect of excess dopamine or norepinephrine.
Hi!
I was diagnosed with ADHD in my early 20’s — about 10 years ago. I tried Adderall with great results but the side effects weren’t tolerable. I switched to Vyvanse but it wasn’t nearly as effective and still gave me a crash. After Vyvanse I swore off prescription drugs — I’m just very sensitive to them and tend to experience all of the side effects. I’m also extremely particular about the foods and supplements that I use and avoid meat, dairy, gmo’s, non-organic produce, processed foods, etc etc.
I started taking MLP about 2 or 3 years ago and have had great results — it’s changed my life. I take 2/day with coffee and the occasional microdose, which is the real sweet spot for me. Recently I find that I’m having a hard time motivating myself and staying focused so I’m wondering what I can safely add to my stack to really get to that next level. I’m back in school (full-time) and will be changing careers in the next 1.5 to 2 years so I really need to be on top of my game right now. I find myself procrastinating more than usual and having an extremely short attention span — trying to mitigate that with more exercise for the time being…
I did get a little impatient recently and decided to try Modalert (I took 1/4 of a 200mg tablet) but it gave me the worst migraine I’ve ever had and I didn’t like how anxious I felt when I ran out of work to do during the second half of my day. I also did more research on potential risks and the list was a bit scary. Medication really just isn’t for me, no matter how hard I try, haha!
So, all this to ask, what natural and well researched/safe supplement would you recommend adding to my MLP stack? Preferably something with low or no side effects (and also safe in the long term.) I’m hoping to gain motivation and focus, but could also benefit from a memory-boost. If it helps, I’m 5’2, 105lbs. Extremely sensitive to everything.
I appreciate your help!
Rhiannon, if you avoid meat and dairy you’re likely low a several vitamins and minerals and there’s not enough L-Tyrosine in MLP. Esp. if you’re truly ADHD.
I suggest you start with the basics. Get yourself a high quality multi like this one: https://www.performancelab.com/products/nutrigenesis-multi-women
Add more L-Tyrosine to your stack and do it twice a day. Morning and noon. Add Alpha GPC to your stack. Morning and noon. Dosage you’ll need to figure out what works for you.
And add DHA to your stack. 1,000 mg in the morning. Like this one: https://amzn.to/2H8iUUy
Thank you, David! I purchased the multi and the DHA as well as (nearly) everything that I found in your recommended stack for adhd. I actually found that stack after posting my original question and decided to go for it!
I do have some questions while I wait for everything to arrive…
How would you recommend layering these — as in which order should I begin to add these to my “stack?” Right now I’m only taking 2 MLP once per day with coffee. I want to avoid scary interactions or negative side effects so I’m wary to start with your recommended regimen of the full stack. I was thinking that I’d start out at once per day and graduate to twice per day, etc. But I’m not sure where to start if I’m taking the gradual route. Maybe adding one new supplement at a time would be best? How long should I wait between adding new ones?
For the above reasons I decided not to add the recommended extra NAFTA and NALT to the stack and just stick with what’s already provided in the MLP and MLEnergy supplements but please let me know if this is unwise and I’ll go ahead and purchase those, as well.
My other question is, are there any known negative effects on the heart, liver, kidneys, etc with any of the items listed in this stack? Have you experienced anything of that nature? Are there things you’d recommend doing or taking to ensure safety and longevity?
Thanks in advance.
Rhiannon
Rhiannon, the smart way to do this is as you suggested. And that’s to add one supplement at a time to your stack and watch for any negative reactions.
Choose any order you want because you should be through your list in a a week. Not sure what “NAFTA” means. But for NALT you may need the extra dopamine so consider adding L-Tyrosine to your stack some time soon. There is some NALT in Mind Lab Pro but not sufficient for most who are ADHD.
There are no known side effects on the organs you list for the average “healthy” person who does not have kidney or liver problems. And as long as you follow dosage recommendations that I provide in my ADHD post you’ll be fine. You can use these supplements for the rest of your life if you need to.
And don’t forget that once a day will only give you benefits for half of the day. You need to dose at least twice if not three times per day for the ADHD brain.
Thank you for the great info! I can’t wait until everything arrives so that I can give everything a try. Appreciate the help!
Hi David,
Do you have any recommendations on taking a probiotic in the morning with mind lab pro? Any benefit to waiting to take the probiotic until later in the morning? Thanks!
Andre, you can use a probiotic at any time of the day or night. But rather than guessing which probiotics my microbiome needs out of 1 – 3,000 different species of bacteria (https://www.ebi.ac.uk/about/news/press-releases/2000-unknown-gut-bacteria-discovered). I’d rather just feed my existing microbiome with a prebiotic and let my gut sort it out.
Works like a charm too. I take it in the morning with Mind Lab Pro.
See my review so you can see more about what I’m talking about: https://nootropicsexpert.com/performance-lab-prebiotic-review/
David– thank you for the great article and website as well. Do you get compensated for the sale of MindPro? Apologies if disclosed somewhere. Thank you.
German, I do make a small commission whenever someone uses my recommendation for to buy Mind Lab Pro. Or any other supplement linked to on Nootropics Expert. It’s how I feed my family and pay for rent.
Hi David:
Can you please do a commentary on a new product called “Matter” by ELYSIUM.
From my initial analysis, this product is just “very good” marketing.
But the ingredients don’t look to be that amazing.
What’s your view ?
John, it’s impossible to tell what’s in this product because I couldn’t find the Supplement Facts label to see what kind of B-Vitamins they’re using. And the quantity of DHA and EPA.
The B-Complex vitamins and DHA are critical for brain health. And everyone should be using them daily anyway. As a stand-alone nootropic when we have something like Mind Lab Pro available? There’s no comparison and it’s not even worth considering.
But a great stack would be Mind Lab Pro + B-Complex $10 + DHA $12.
Hi Mr. Tomen,
I am so grateful I found your site, thank you so much for all that you do. I just watched your phosphatidylcholine video on YT and wanted to check in with you before I purchase it. My main reason to take it is for brain health and liver support since I no longer have my gallbladder =( .
I do not want to take a soy product so that rules out a lot of pills that are advertised as phosphatidylcholine. I found a pure sunflower lecithin powder (NOW brand) that says that sunflower lecithin has phosphatidylcholine naturally and under the nutrition facts it states that it naturally contains 2,500 mg of phosphatidylcholine for every 1 and 1/3 tablespoon of the powder.
I know you mentioned that lecithin is not the same as PC so I am wondering if the NOW brand of PC is legit PC? Or if you could suggest a brand that is not from soy?
Your time and response is greatly appreciated… thank you so much!
Yesenia, NOW Foods is one of the manufacturers I trust. If their label states that the PC is from “sunflower lecithin”, I trust that it does. The company has an extensive testing program (https://www.nowfoods.com/now/quality-safety). And I’m sure they’d provide a Certificate of Analysis if you asked for one.
Is MindLabPro and Performance Lab Mind made by same company?
Bill, Mind Lab Pro and the Performance Lab line of supplements are made by Opti Nutra Ltd. It’s a UK company and the supplements are made in the USA.
HI David, thanks so much for such great in depth info.
I’ve been taking MLP for 3 months, now.
I’ve recently been prescribed Jornay PM for ADD, which is taken at night and the capsule dissolves in 12 hours and releases Methylphenidate (Ritalin)
I also take Fish oil, multivitamin, vitamin C, Magnesium supplement throughout the day.
When the stims are working, i feel a tightening in my shoulder/neck area and it switches sides. What would you recommend for softening the harshness of the stims side effects?
You also mentioned taking NALT and ALCAR with stims. Any other recommendations when on stims?
Thanks in advance.
Marcus, my entire ADD stack is detailed in this post: https://nootropicsexpert.com/best-nootropics-for-adhd-add/. Using that stack as I describe including dosage and timing should help.
But it sounds like your system is using that newly released dopamine and turning it into norepinephrine. Only way to deal with that is a norepinephrine blocker. In med terms those are called beta blockers.
DHA and magnesium will help a little. But the only true natural beta blocker I know of is one I haven’t researched or reviewed. And that’s Hawthorn: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249900/. And possibly Rauwolfia serpentina (Indian Snakeroot) which I know nothing about.
Hey Dave,
There’s a product called Dynamic Brain which is produced by Stonehenge Health, have you heard of it or have any opinions on if it’s as good as advertised? Thanks hope to hear back soon.
Kyhle, never heard of it so I looked it up. It’s a low quality multivitamin using synthetics and ground up rock for minerals. And a “proprietary blend” of various nootropics at a dose so low they’re useless. And they include Huperzine-A in their “blend” which cannot be used but every 2nd or 3rd day. Good thing they have a money back guarantee.
Thanks for getting back to me so quickly, so you’re saying Mind Lab Pro is the best product on the market? Also you’re basically saying the dynamic brain nootropics aren’t weak & not worth it? Also have you heard of Kanna, PHenibut & deprenyl?? If so are they a good combo w MLP? Thanks for responding
Kyle, Mind Lab Pro is still the benchmark that other companies try to match. And so far no one has. I know because I’ve tried all the other top pre-made stacks on the market. At the request of the manufacturer.
The Dynamic Brain product is just not good quality and a poorly designed formula. It’s not even close to the other premium pre-made nootropic stacks on the market. Not even including Mind Lab Pro. It’s absolutely not worth any price they are asking for it.
I don’t know what Kanna is. Phenibut is not to be toyed with. It’s difficult to dose and subject to abuse because of the way it works.
L-Deprenyl is an MAOI and prescription drug in most countries. There’s no need to use because we have other natural MAOIs that work just as well.
Mind Lab Pro does not need anything else to help it work. Certainly none of the three you mentioned. It just works. But if you’re clinically ADD/ADHD you do need to add extra L-Tyrosine and possibly ALCAR and Alpha GPC or CDP-Choline to it. If you’re generally healthy you can use it on its own.
Thanks a lot David, you answered everything thoroughly & to the point! I do have ADD, was prescribed adderall years ago but had to stop bc of not being able to eat & it enhancing my anxiety horribly. I think I’m gonna try the MLP & add the other supplements you provided.
1 more thing there’s actually a product called NZT-48 have you heard anything about it? They’re obv. Copying the e act drug from the movie limitless! Just wondering if you heard anything about it, thanks again my man!
Kyle, I looked into “NZT-48” sometime ago and all I remember was that I wasn’t impressed. Except for their clever hook into the movie Limitless. And that’s the last time I’ve thought of it until you brought it up.
The protocol I outline in my ADD/ADHD post works for a lot of us. Try it and see if it works for you. And don’t be tempted by “shiny objects” because they’re just a distraction. And will slow your recovery.
Hi David,
I’m about to order my first 3(4) bottles of MindLabPro and I was wondering what’s the best way to take MindLabPro while doing intermittent fasting at the same time?
Label on the bottle states: “Take two (2) capsules in the morning or early afternoon, preferably with food” – does this mean some of the ingredients are fat soluble, ie. best taken with fats for full absorption?If this is the case, I’ll need to move my eating window. I fast for 20h and eat for 4h, my first meal is at 5pm and last at 9pm (doesn’t align with MLP recommendation).
What would be your advice on how to incorporate these two together for maximum benefits (both from MLP and fasting)?
Some of the ingredients in Mind Lab Pro are fat-soluble and need a healthy fat for delivery through cell membranes. For example Bacopa Monnieri and Phosphatidylserine are fat-soluble.
But you can get around this restriction by taking it with MCT Oil which shouldn’t break your fast. Because while it’s a “healthy fat” your body immediately turns it into ketones. Would that work for you?
i used modafinil first, enjoyed 3 months, then suffering now ,bcos internally i am weak, all
medicines create tolerance including nootropics, not able to find some permanent solution ,trying
all sorts of pills to solve mind issues ,
Jain, nootropics do NOT cause tolerance if you know how to use them. I sent a newsletter out awhile ago that addresses tolerance issues. Why it happens and how to avoid it. You can read that article here: https://mailchi.mp/31ec6378a9f4/how-to-avoid-nootropic-tolerance
You say that you are “internally weak”. Nootropics can help alleviate at least some of those symptoms. They saved my life. You’ve hundreds of pages and posts here on Nootropics Expert that can help. I humbly suggest you start searching using the search function top right for your specific issues. And get the answers you need if you want to get better.
Hello David I’m new to nootropics. I’m considering taking Mind Lab Pro. I have depression anxiety and brain fog. I want to add Aniracetam and Sulbutiamine. How much Choline do i need to add and what kind. Also what do you think of Nootropics depot. Thank you very much.
Mike, 750 mg of Aniracetam in general requires an extra 300 – 600 mg CDP-Choline or Alpha GPC. I prefer the latter because I get some CDP-Choline (Citicoline) in Mind Lab Pro.
I’ve ordered from Nootropics Depot in the past and their shipping and quality was good. But my preferred source for Aniracetam now is HR Supplements in Nevada. Link is near the bottom of my Aniracetam review. And Double Wood Supplements for Sulbutiamine which also has a link near the bottom of that review.
I’m careful about who I get my supplements from. And I know those two companies have an extensive testing regimen for each batch of supplements they produce. I can’t say that for sure about Nootropics Depot. Not saying they don’t. I’m just not sure.
Thank you David
Hi David,
If taking 750mg Aniracetam would you double the dose of Choline mentioned here and should the Choline be taken twice a day / at the same time as the Aniracetam?
Thanks.
Jamie, you should be using a choline supplement each time you use Aniracetam. But how much is dependent on how much your brain needs. And varies from person to person.
I use another 300 mg Alpha GPC on top of Mind Lab Pro when using Aniracetam. You may not need as much. Try double the dose and if you start feeling sleepy or fatigued that’s too much acetylcholine. In that case you’d cut back on your choline dose.
Thanks in advance for answering my question. What are the advantages (if any) to combining Mind Pro Lab and ThyNatural for my issues with hypothyroid symptoms.
Philip, Hypothyroidism causes major problems with cognition and the brain. Mind Lab Pro helps restore some of the functions impacted by being hypo. For example, MLP contains N-Acetyl L-Tyrosine (NALT). Thyroid hormone is made using iodine, selenium and L-Tyrosine.
Hello, thanks a lot for all the great information you provide. Do you have a preference between Mind Lab Pro and Qualia (caffeine free)?
Fe, I’ve used Mind Lab Pro for the last 5 years and have tried Qualia for a couple of weeks as well.
And I still prefer and recommend Mind Lab Pro because it works better and is less expensive.
Dear David,
First of all, thank you for your useful articles and insights.
Is it ok to use MLP with Lamictal? I have been using Lamictal for the last 3 years, I am diagnosed with bipolar disorder but I have no symptoms of it from the time I am on Lamictal.
Thank you in advance for your answer.
With best regards,
Richard
Richard, Lamotrigine (Lamictal) appears to increase the action of GABA, and inhibits voltage-sensitive sodium channels according to the National Institute of Health. I’m not aware of any direct contraindication with any of the ingredients in Mind Lab Pro.
But to be safe I suggest you check each ingredient against Lamotrigine before using it. It’ll take a little time but it’s well worth the effort. I like using this drug checker for this type of thing: https://www.drugs.com/drug_interactions.html.
Enter “Lamotrigine” in the search field, click “ADD” and then “Check for Interactions”. You’ll get a list of all the drugs and supplements that interact with this drug with a detailed explanation for each thing that turns up in the list.
Hello David,
Thank you very much for your answer. I will check it out.
Have a great day,
R.
Can you give me the best 3 or 4 nootropics for a 57 year old male who is busy raising 2 teenage boys, for memory, cognition, focus and brain energy?
Troy, select one nootropic from each of the five categories in this post: https://nootropicsexpert.com/best-nootropics-for-the-aging-brain/
Hi David, I’ve been taking MLP for a few months now and I had been wondering about cycling off of MLP as they suggest and I believe that question was answered in one of your replies back in June. This brings me to another question: Do you see any issues with adding 300 mg of uridine monophosphate and 750 mg of anaracetam to a two capsule dose of MLP in the mornings? A bit off topic, but still related to cycling, does t-booster from PL need to be cycled as they suggest?
Larry, you should be able to stack those two nootropics with Mind Lab Pro without any problems. I use Aniracetam with it daily with great results.
This question of ‘tolerance’ keeps on coming up. So I’m going to do the research and send an email to everyone with what I find. I personally have never found the need to cycle anything in my stack. But it may be just me. I’ll let you know what turns up in my research.
Thanks David. I too haven’t really seen a need to cycle anything due to ‘tolerance’ issues; that even includes daily modafinil for well over a year. However, after becoming familiar with your detailed reports, I would definitely be interested in the results of the email you mentioned.
Hello! Is it okay to stack Mind Lab Pro with LumiDay? I can’t find anything on your website about LumiDay.
Thank you
Iris, shouldn’t be a problem.
Hello David, first let me say glad you’re doing better from your hospital stay a few months back your contributions to the nootropic field are invaluable! With that being said I have two questions:one will Mindlab pro be offering any discounts again for your subscribers and two will you also be offering again discounts for your Consultation Sessions?
Thank you Portress. I wish I knew when another discount was coming our way but I don’t. Sorry.
As for discounting consultation sessions, I’m very reluctant to do it because it takes so much of my time. The last time I ran a sale on consultations I was swamped and couldn’t get anything else done.
Keep in mind Nootropics Expert is still a solo operation. I do have a little help from a developer. But that’s it. I don’t even have an assistant yet. So all reviews, posts, YouTube videos, email newsletters, Facebook posts and answering questions, books, and responding to comments and questions comes from me. So I need to make choice who gets the most benefit from my time.
Hi – thank you for the very informative site. I appreciate that you take this seriously, respond quickly and offer great advice.
My story – 57 y.o F, 5′, 112# (used to be 90-95 which was my preferred weight) married (w/no ‘human’ children (1 if I include my husband :-)), 2 dogs, 7 chickens, with lack for life. I work from home doing medical coding. Zero exercise (unmotivated), nicotine use (‘just’ started the 14mg patch-OTC), beer, bad diet, stress.
I suffered from 3 ‘back-to-back’ family deaths (mother age 83 (expected), brother 55 (1.5 yrs later – drug overdose (surprising, but not), sister 57 (2-years later, cancer (metastatic brain from lung) – COMPLETE devastation for me (she never did drugs or smoked, she ate well and exercised). After her death (2017) I gave up. Oddly – I started smoking and drinking. One would think ‘why’ smoke after this, but that is the part I gave up – I didn’t care.
I am interested in this MLP stack as 1) I am not one to take multiple supplements throughout day; 2) I want to go from A – Z in 5 seconds; 3) I would like to get ‘zest’ back in my life (basic house work, better care of animals (I’m depressed, they’re depressed)); 4) I need to continue to learn for my job (taking tests, courses, etc. that I am unmotivated to do currently); 5) I suffer no real ailments outside of the depressed mode, rarely need and/or take any type of OTC pain meds (I will only take acetaminophen-type when needed (which is rarely); 6) insomnia – but I strongly believe that is alcohol-related (2-4 beers/day).
I thought this would be a good start for me. I’m confident that once my chemicals are balanced other things will fall into place. How to get that balance is my issue. I know that diet, exercise, etc will help tremendously, but to get that motivation is where I’m lacking.
My goals are: quit smoking; learn and comprehend for test taking and courses; motivation to do things-which I then think other life-things will fall into place.
Is this a good start point for me? While I don’t want to take a hand-full of supplements do you ‘see’ anything else that I may benefit from? If so, dosage, etc.
Thank you very much in advance. Cam (PS-I like also that you added in post re: why this product is not offered on other websites – make perfect sense.)
Camilla, Mind Lab Pro is certainly a good start but at your age and with what you described is unlikely to be enough. There really is no “one-pill” solution no matter what the ‘experts’ say.
If not for anyone else, do it for your kids. Experiment with some other nootropics until you find some that work for you. Because they really do work if you’re willing to put in the effort.
Scroll down the list of posts here: https://nootropicsexpert.com/category/guides/. And look for my posts on “motivation”, “depression”, and there one on energy somewhere around here.
Get started with MLP and then after reading those posts, try a couple of nootropics that resonate with you. Keep on experimenting until you feel better. I know it will because 10’s of thousands of people in the Nootropics Expert community have said that it will. It did for them. It can for you too.
My first update in a while- hope you will have time to respond. Speaking of which, tracking responses and answers on this site is somewhat cumbersome, would be nice to see an auto response and reply function.
I’ve been on MLP 2 mos, coincidentally with Harvoni treatment for HCV. I was asked to discontinue my over the counter supp’s but that really wasn’t realistic due to side effects of increased anxiety. So I have continued MLP, 5HTP, GABA, NALT. Have completed the treatment but with a 48 hr half life it will be ~~2weeks before it’s out of my system. Although the md’s don’t tell you, one of the major impacts of the treatment is eradication of the virus from the brain, the secondary primary site of HCV replication…so while my body is clearing out I want to make an extra effort to take care of the gray matter. MLP is good but not spectacular. Exploring options. I’m on the low end of dose, 2/day. Considering 3/day? Have also looked at Akua Life Neuro, primarily for Lions Mane dose, but thinking the two together might stack well. Or just adding lions mane to MLP. Lots of options here with just these three components. Any suggestions/guidance HUGELY appreciated.
Be well, be good.
James, you can increase Mind Lab Pro to 4 capsules per day. Two in the morning and two at noon. But I agree that Neuro-Stack by Akua Life in your case could work wonders. Because it’s got such a high dose of Lion’s Mane Mushroom for neurogenesis. I’ve used the combo of MLP and Neuro-Stack and like the result. http://www.akualife.com?aff=15
Or would it be better price performance to just add a lions mane supplement? Any supplier you would recommend?
James, other than the Lion’s Mane that is in Mind Lab Pro, Neuro-Stack is the only one I can vouch for for high quality.
Fyi, also looking at a CBD “trial” using Feals Flight product. Any thoughts?
James, I think CBD Oil is great depending on what you are trying to achieve. But I’m not familiar with that company.
Hi David
I have just started nootropic one month ago and my first stack is mind lab pro. I took 2 capsule for the first 5 days and the results was amazing but on the 6th day the effects are gone. What can I do now?
I read about your article and realize I have all the symptoms of ADD. I do also have anxiety , low motivation, unable to concentrate and unwilling to learn new stuff , proscratination and social anxiety too. I have suffer the above symptoms for last 20 years and didn’t know it was an brain problem
I am currently started one month ago on noostropics stack.
Morning
Multivitamin x 1
MindLab pro x 1
L x 1
B6 x 1 (100mg)
Vitamin C (1000mg)
L tryrosine ( 1500mg)
Noon
Curcumin x 2
Reservatrol x 1
Mind lab pro x 1
Evening
L Tryptophan ( 1000mg)
B6 (100mg)
DHA ( 1000mg)
I am on the 28th day of mind lab pro and should I cycle it 5 days or just discontinue using it as I do feel the effects anymore. Kindly advice me. Thanks .
Kong, welcome to our world of nootropics. The funny thing about using nootropics is once your brain starts working better, after awhile you get accustomed to the “new you” and don’t notice the improvements any more.
So the question is are you looking for the “wow” factor? Or do you just want your brain working the way it was originally designed? If the latter then forget about cycling and use your stack every day. And as you learn more experiment with different things to tweak what you’ve already done.
Hi. Thanks for the reply. Your reply was the same as how the customer service reply me when I ask them.
The first 5 days after taking mine lab pro was that I was feel so energetic and my mood was better. I didn’t think of any negative things but the problem is I do get insomnia. On the 6th day. I was back to the lethargic me . The same as before I took mind lab pro.
Kong, there is no logical explanation for what you are experiencing without knowing much much more about your medical history, other meds your are using, other supplements, your living environment, diet, etc. And this comments is not the place to dig into this for confidentiality reasons and time. You can do more research on your own and try to figure out what’s going on in your situation. Or book a personal consultation with me to help you sort it out.
hi David
My father suffers from Alzheimer’s disease and has a problem swallowing pills. is it possible to mix the MLP with dates or with milk
Mohammed, you can certainly open the capsules and put them into a drink.
Hi David,
I’ve been experimenting for years now with different combinations of nootropics. At times I get great benefits, but I have a hard time isolating what combinations are working and which aren’t (partly due to my own inconsistency with keeping steady schedules and adding/taking away supplements without proper testing time). Your advice and tips on the Mind Labs and Performance Labs prestacks are a godsend for me as it will simplify my supplementation. I was curious if you take both every day? Presumably the MindLab Pro during the day and Performance Labs Sleep at night?
Thanks!!!
Ryan, Performance Lab Sleep about 60 mins. before bed and Mind Lab Pro in the morning. If you think you need it then take another dose of MLP at noon.
Hi there David,
Currently I’m taking Noocube, will it be safe to combine the Noocube Nootropic stack with Mind Lab Pro? I’m looking into improving my focus, memory retention and retrieval, anxiety and depression, and overall health.
I’ve tried Peformance Lab Mind but not much of an affect, as you stated in your previous videos that the ingredients are under dosed.
Kind Regards,
Rami Abbas
Rami, take a look at the ingredients in both stacks. Are the ingredients when combined under-dosed or too much? You should be able to combine them. But will they help with anxiety and depression? It depends on the root cause of both and if they are being addressed.
I’ve been taking MLP for 5 days- I seem to be one of the fortunate ones who perceive positive effects quickly. I plan to monitor effects closely and add singular nootropics as needed- I’m Bipolar. So I’m weaning off scrips, which I hope to complete in the next 30 days. I am continuing to take Chinese 7 Sacred Mushrooms (Naturealm) in the morning with coffee- gets into the bloodstream/brain quickly and then I slide into the MLP- highly recommended!
Just my thoughts and feedback- hope all enjoy and receive the benefits of this path…
Does Mind Lab Pro contain a GABA analogue?
James, no, Mind Lab Pro does not contain a GABA analogue.
Hello my friend I have a question… does mind lab pro help with fuzzy thinking? Because before 7 months I started having depression problems and one of the symptoms of depression is fuzzy thinking… btw I went to a doctor and he gave me medicine for my depression and everything is ok know but the fuzzy thinking is still here
Ali, if by “fuzzy thinking” you mean brain fog then Mind Lab Pro may help. It depends of course on what is causing the fuzzy thinking. It may be caused by the antidepressant you are using.
Hello David, I just orderder MLP based on your recommendations! 3 bottles + 1 free. After the purchase, I started searching on google about the product and didn’t find sources outside the “nootropic world”. IT does not bother me at all because I trust the information you provide and that’s why I jumped to buy it w/o doing a research of my own… but then I read they manufacture the product in the USA under Optinutra company, but I just can find any information about the location of the manufacturing facility or the company. My question is: Do you know where in the US are they located? Have you seen some, or all of the certificates they said they have in this factory? I think more information will provide more confidence to attract potential customers. Thank you.
Francisco, please email the Customer Service contact at Mind Lab Pro for that information.
I’ll start out with the ugly news- I’m Bipolar. Diagnosed~15 years ago. I have been on a variety of psycho scrips since then, most recently lithium carbonate, Olanzapine, and Lamotrogine(some seizures, a la grand Mal).
For the last two months I have been experimenting with nootropics, with very positive results I believe. Primarily GABA, Tyrosine, Inositol and lithium orotate- I also take a hodgepodge of more traditional supplements like Turmeric, high dose Fish Oil, some vits, etc.
Now I’m considering Mind Lab Pro- thinking I will get a broader range of ingredients that will be beneficial for my BP, and it will be better price performance…?
Any comments and/or suggestions greatly appreciated- I enjoy your vids- they seem to be well thought out, thorough, and trustworthy. Rgds…jwf2
James, seems like you are on the right track. Keep on experimenting until you find exactly what works for you. Mind Lab Pro would be a great addition. But please be very careful about combining certain nootropics with prescription meds. Because Serotonin Syndrome is real and can be deadly if you are not careful.
Gotcha. I am slowly weaning my self off all the scrips except I have converted from the carbonate form of lithium to orotate. Two down two to go- I’m hoping the MLP will help get me over the hump.
Thank you for all your effort!
Hi David,
I’ve been taking Mind lab pro (2 in the morning and 2 in the afternoon), Performance energy lab (2 morning and 2 afternoon), Alcar (600mg morning and 600mg afternoon), Nalt (600mg morning and 600mg afternoon) and alpha liopoic acid (600mg in the morning) I take this with MCT oil and either ritalin or concerta. Unfortunately I dont feel much of a difference. I still experience the stimulant crash and on my off days when I dont take my ADD meds, I dont feel the effects of the supplements. My motivation is still low, memory isn’t the greatest and still suffer from fatigue. I have read your posts on memory, fatigue and add however there’s so many different type of supplements you recommend and it’s quite confusing. Do you have any advice you could provide me with (changing my dosage, adding additional supplements to my stack etc) as exams are coming up and I really need to step up my game.
Thanks in advance.
Zey, this will take some experimenting on your part. I suggest dosing MLP, PL Energy, NALT, and ALCAR first thing in the morning and at noon. Then another dose of NALT and ALCAR later in the afternoon (i.e. 4 pm) should eliminate the stimulant crash.
If you’ve read my story, you’ll know that I tried that stack for a year while not using Ritalin and it worked for me. But why do you have “off days” when you don’t use your meds?
Another suggestion is replace NALT with standard L-Tyrosine. It works better for some people. And depending on your age, you many want to increase your NALT or L-Tyrosine dose to 750 or 800 mg. The aging brain loses 10% of its dopamine-making capacity each decade starting in your 20’s. And as you get older, monoamine oxidase increases which further depletes dopamine.
Not sure what you mean by “feel the effects of the supplements” but assuming you just want relief from ADHD symptoms and not a feeling of euphoria, you need to find your sweet spot for dopamine and acetylcholine.
BTW, if you are using Performance Lab Energy morning and noon, there’s no need to use additional alpha lipoic acid.
Hello David, I’m on Lexapro, can I use MLP with an ssri?
Thank you
Otto
Otto, it depends on how sensitive you are to meds and supplements. There is nothing in Mind Lab Pro that directly promotes serotonin. Which is what you need to be careful of with SSRIs and nootropics. Serotonin Syndrome is nothing to mess around with.
A standard Mind Lab Pro dose is two capsules. So you may want to consider trying a single capsule first and see how you feel.
My recent bloodwork indicated that I was not deficient in any B vitamins and actually had a high level of vitamin B6. Would it be harmful to take a supplement containing vitamin B6 or any other B vitamins for that matter.
I struggle with severe social anxiety and I would like to take a formula like Mind Lab Pro but am concerned with the B vitamins.
Annette, it’s good to be concerned but in this case, it’s not a problem. Because the form of vitamins in Mind Lab Pro are low enough and the right type that you don’t need to be concerned with overdoing it. Vitamin B6 as P-5-P is non-toxic and what your body recognizes instantly as B6. Synthetic B6 would be a problem.
Have you seen my post on social anxiety? https://nootropicsexpert.com/best-nootropics-for-social-anxiety/. If you can figure out the root cause of your anxiety it would be easier to address. But if you are guessing then it’ll take some trial and error to find the right solution.
You may want to start with something like Lemon Balm and/or Gotu Kola and see if that helps. Because they act more as adaptogens and hopefully could bring back some balance to your system.
Hi David, emailed the CS and it is all okay now.
Now waiting my Noopept and Aniracetam and hopefully this stack work for me.
Cheers
Hi David,
Thank you for all the information you gave, it’s been very helpful.
If I would like to stack Mindlabpro with Noopept and Aniracetam, what is the good starting dosage and best time to take it?
Do you have any Discount Code to share for MLP? NE10 is not useable anymore.
Best Regards
Ikmal, follow the dosage recommendations in the individual reviews for Noopept and Aniracetam;
https://nootropicsexpert.com/aniracetam/
https://nootropicsexpert.com/noopept/
I’ll check into the discount code situation. First I’ve heard of it and was not told that it had expired. It’s the only one I have so I’ll check with Opti Nutra later today.
Thank you for the reply David,
I just wonder if I were to stack with MLP, should I reduce the dosage of the Noopept and Aniracetam?
Ikmal, it depends on how you react to these supplements. I don’t reduce my dosage of Noopept or Aniracetam when using MLP. But that works for me. You may be different. I suggest experimenting with lower dosages and work your way up to find out.
David,noted. I will start with half the normal dosage for 2 weeks and see how it affects me.
Any reply from Opti Nutra regarding the “NE10”?
Best Regards
Ikmal, I was just told my Opti Nutra that the coupon code is could until Feb. 15, 2019. So it should work. It if doesn’t I suggest contacting their Customer Support and find out why.
Hi David-
I am taking Mind Lab Pro and have taken one pill for the past 4 days. I feel somewhat moody and edgy. Is this common? Have you ever heard of this happening?
I was taking another form of liquid Lions Mane and also take a keto nootropic powder shake made by perfect Keto. I was planning on eliminating that once I saw how Mind Lab pro worked- I am focused and brain fog is gone but I do not like feeling edgy and snappy. Thoughts?
Jeanee, edginess is likely caused by excess norepinephrine. Mind Lab Pro contains NALT which boosts dopamine which then converts to norepinephrine.
It’s possible that you are extremely sensitive to increased dopamine. Or there is something in the ‘perfect Keto’ powder you are using that is also boosting dopamine or norepinephrine.
David: Opti-Nutra recommends cycling Mind lab Pro either 5 days on and 2 off or 4 weeks on and a week off. I notice you take it daily. Opti-Nutra claims the brain performs better using the cycling method. What say you?
Dennis, cycling Mind Lab Pro may work better for some people. But that has not been my experience. I’ve been using it daily since late 2015 and it’s made a huge difference in my life.
Everyone is wired different a sometimes looking for a different experience from using nootropics. I suggest you try using it daily for a month and the next month try cycling. And see if you notice any difference.
Hi David,
I just wanted to take the opportunity to thank you for this outstanding site, as well as your video’s which are enormously helpful.
I have been suffering extreme fatigue over the last couple of years, exacerbated by a separation early last year and becoming a single dad with little to no support from my ex partner.
I was also suffering depression and was seeing a professional, who prescribed Duloxitine which is an SSNRI and that probably helped get me through the worst of the separation but it blunted me to the point where i almost stopped working. I’ve since come off that (very happily!).
My fatigue got the point where i had to sleep in the afternoons and my work suffered causing my income to virtually stop. I’m self employed so that isn’t a great look – no fall back.
I decided to try Modafinil and that’s been a godsend, but it’s not the wonder pill many bang on about, at least for me. That said, most days, it keeps me awake which is fantastic and an excellent starting point to getting back on track.
I’ve since been looking at Nootropics, and I also happen to have some MLP which i tried a few years ago without any positive results, but I stopped them too quickly.
So I’ve been trying various stacks for about 6 weeks not and here’s the current one I’m trying now:
Morning
Modafinil 100mg
L-Theanine 200mg
MACA – 5grams (I think maybe that’s too much)
Alpha GPC – 300mg
Vitamin D3 5000ui
Omega 3 – 2000mg
Dopa Munuca – 60mg
B Complex
Multi Vitamins
Mind Lab Pro – 2 x caps
SAM-e – I’ve ordered this but its not arrived yet
Night
5HTP 200mg
Now Sports ZMA – 3 caps for the magnesium 450mg
I also take the odd Oxiracetam along with another Alpha GPC from time to time, but I don’t notice any change.
So far, this stak appears to be working, i no longer have any brain fog, i can barely remember what it feels like to have it actually. My mind is much clearer and I have much more motivation in the mornings, but afternoons are still very difficult. So there’s an improvement, but not yet where i need/want it to be.
What I’m looking for is –
Energy
Focus
Motivation
Stamina (I’m a recruiter so I need to sit in front of a PC searching for candidates, reading CVs, interviewing and presenting to clients all day – about 10 hours a day)
I’ve ordered Noopept and SAM-e to test them out too. The SAM-e was based on your advice to help balance serotonin and dopamine as I am taking L Dopa and 5HTP.
Is there anything you’d change in that stack?
Also, which racetam might you choose as an alternate to Oxiracetam?
I know this is a long email, I appreciate your time reading it!
Cheers,
Dave.
Dave, you’re definitely on the right track. The one thing that jumped out at my was you high dose of 5-HTP. I suggest re-visiting that one. Take a look at my sleep posts because you may be able to get the sleep you need by naturally boosting melatonin with something like tart cherry juice. Or Performance Lab Sleep.
I’d also consider increasing your dopamine precursors. Either add NALT and/or increase your dosage of Mucuna.
Noopept is a good option. I find that my productivity increases when using it. And I’d choose Aniracetam before Oxiracetam. Double or triple your Alpha GPC dose.
And consider changing your dosage schedule so your taking some of these half in the morning and half at noon. And consider trying some NALT and ALCAR around 4 pm. Each time you dose should be with a high quality fat like unrefined coconut oil.
Wow, that was fast! Thank you so much, I will try your suggestions and report back 🙂
OK thanks for such a quick reply!
If I add NALT in the afternoon, along with ALCAR, given i already take L Dopa and I’m looking to increase that – would that be too much dopamine in the stack?
I’ll try your suggestions and report back! Thank you 🙂
Dave, it may be too much dopamine but the only way to find out is try it. Look up symptoms of excess dopamine so you can tell if you over did it.
BTW, I do offer personal consultations as time permits. Please send me an email using the contact form (link in the footer) and I’ll get back to you.
OK, I’ll try it out 🙂
Message sent with email BTW..
Cheers,
Dave.
Hi Again David, Further to my last message, I forgot to ask you whether you offer personal consults and if so, what do you charge for them? Maybe if you could email directly with details?
I also mentioned I’m looking for:
Energy
Focus
Motivation
Stamina
I forgot to add the following:
Mood enhancement – I’m still suffering from depression, but it has improved a little.
Anxiety – I Want less of it! It’s what i think is the main reason my work has suffered, I can’t bare the thought of picking up the phone most days.
Thanks,
Dave.
Hi David,
What is the right time to take MLP (morning empty stomach or in the evening)
Thanks
Sushil, you can take Mind Lab Pro in the morning or early afternoon with or without food.
Hello David,
First thank you for your website.
I am not sure to understand this answer as I thought you mentioned that NALT shouldn’t be taken with food.
Did I miss something ?
Thank you
David, NALT is an amino acid and food that includes meat is also amino acids. Taken together means NALT needs to compete with the same amino acid transporters as those from food. If you take NALT with a meal chances are you will not experience the same benefit as you would taken an hour before or two hours after a meal.
Hi David!
I was on PL website for their Whole-Food Multi and discovered their other interesting formulas.
One of them looks like a reduced version of Mind Lab Pro.
It is simply called Mind, and contains only some of the ingredients of MLP:
Citicoline (Cognizin®), 250mg (same quantity)
Phosphatidylserine (Sharp PS® Green), 100mg (same)
N-Acetyl-L-Tyrosine, 300mg (more)
Maritime Pine Bark Extract (standardised for min. 95% proanthocyanidins), 75mg (same).
For a reduced price (about 20%), and considering taking it with their multi, what are your thoughts on that?
Would you suggest me to try it, or to stick to the big brother?
Thank you!
Andrea, you are correct in you evaluation. Performance Lab Mind was designed to be used with a multivitamin. In particular the B-Vitamins critical for neurotransmitter synthesis.
My favorite is using Mind Lab Pro with the Performance Lab Multi. But you should have similar results using the combo you just discovered.
Lovely, thank you!
The only problem I have with Mind Lab Pro is that I can’t get an answer from them concerning the quality of their Lion’s Mane. I have asked what the mushroom is grown on, where it’s grown and the minimum percentage of glucans.
Finally, I was told that their Lion’s Mane has a minimum of 25% Polysaccharides. But, that doesn’t necessarily speak to the quality of the mushroom. After asking for an update about a week later they told me they would have to forward my request to a colleague. I never heard back. So I sent another email a few days later and they said my questions have been sent to their “manager, who is currently out of the office”… I never heard back.
So it came time to reorder a couple weeks later and so I sent over another email asking if they have been able to get my questions answered and I simplified my questions to what is the beta-glucan content and what is the starch content of their Lion’s Mane mushroom. I was promptly told that my inquiry has already been forwarded to our R&D team but that they would send a follow up message to them. It’s now been a few more days and I have still not heard back from them.
I will update this or send a follow-up reply if I ever hear back from them, but it seems I’m getting the serious run-around as to my questions concerning the quality of the Lion’s Mane in Mind Lab Pro.
Having said all of that, the other ingredients within Mind Lab Pro are well defined and of high quality and still make this product worth the purchase price, but anyone taking this product expecting much from the Lion’s Mane should adjust your expectations until they make a statement concerning the starch content and the beta-glucan content of their Lion’s Mane. I would actually pay more if this is a high quality Lion’s Mane or if they switched to a proven high quality Lion’s Mane mushroom, but as presently stated, I have no idea if it is.
Jason, I highly doubt you’ll be able to find out what the mushroom is grown on. According to Cornell University there is only so many ways to commercially grow Lion’s Mane Mushroom: http://smallfarms.cornell.edu/2015/04/06/lions-mane/
I suggest contacting the Customer Service team at Mind Lab Pro again and asking specifically for a “Certificate of Analysis” for the Lion’s Mane they’ve used in the last batch of MLP. If you feel like you are getting the ‘run-around’ tell them David Tomen from Nootropics Expert specifically said to ask for the CofA.
I know that these guys test and test their products before, during and after encapsulation. This information is available. But I also know that their business is growing like crazy because it’s a good product. And they’re doing their best to keep up in the Customer Service area. Including hiring more people.
Let me know later this week if you’ve received what you are looking for by responding to this comment.
Hello Mr. David Tuman,
A month ago I started taking Mind Pro.
Next week I have an important test.
Currently I use: Attent (Adderall) 30mg At 11 am + 30mg At 15 pm
It helps me.
I take 60mg at one time – it works much better, but in the evening it’s over – I’m very tired.
I have concentration problems and some anxieties. The pills help me and the situation has improved but the problems still exist and I still have trouble concentrating.
So I also take nutritional supplements:
That I get up in the morning – before the meal – L-Carnosine 500 mg
After half an hour / hour, I eat breakfast and then I take-
DMAE, 250 mg
+
ActiveBrain:
(Phosphatidyl Serine 100 mg Phosphate Acid 100 mg)
+
HTP-5 100 mg
+
Omega-3
+
Mind Lab Pro
+
B-Complex 50
At 10-11 pm:
GABA 500 mg
At 11-12 pm:
Melatonin 5 mg
All this I started taking two months ago. That does not help me. the opposite. Since then I have not been able to learn well.
Next week I have a very important test.
I wanted to ask, did – what I take, that much?
What is their combined interaction?
What is allowed to take together? What time of day?
Is before food / after?
What do you recommend for the day of the test? (The test from morning to night).
Thank you for your help.
HAREL
Harel, first you are likely using far too much melatonin. For better sleep, please see this post for melatonin alternatives > https://nootropicsexpert.com/best-nootropics-for-sleep/
Please review the following stack that was designed for those dealing with ADD or ADHD and are using stimulants > https://nootropicsexpert.com/best-nootropics-for-adhd-add/. Notice the last dosage late afternoon. That is used to prevent the stimulant crash you are currently experiencing.
Mr. Tomen, is there any other way to make an order besides using a credit card. I have tried 2 times with no avail.
Jennifer, you’ll need to contact Mind Lab Pro directly for this. You can reach their customer service team here > https://www.mindlabpro.com/contacts/
Hi David,
I have been suffering with depression and anxiety ever since I was 12. I’m now 32 and have been on nearly every ssri, snsri, nri, trycyclic and mood stabilizer known to modern medicine with very little and/or only short lived success and always with uncomfortable or even unbearable side effects.
In January this year I decided to cut all the crap and go medication free! I could only hack this till just after my birthday in May when I (unfortunately- if only I had read this blog first!) Started taking 5htp, needless to say it didn’t work. I then tried vortioxetine (brintellix/trintellix) only lasted on it for 3 and a half weeks due to severe gastric upset.
To top it all off, most of this year has been spent in and out of hospital with an array of debilitating symptoms which has culminated in a diagnosis of chronic fatigue syndrome/me and severe osteoarthritis in my cervical spine. I have spent the last few months researching the best way to end my life but despite my constant pain, anguish, brainfog and thorough torment I have come to the conclusion that I haven’t got the balls to do it and that somehow (f**k knows how) my body and/or brain wants me to live.
I have a good diet and I am currently taking:
A good food based multinutrient, natural b complex and high quality fish oil and extra magnesium (transdermal oil spray) and mega spore probiotic also 3 monthly b12 injections
ativan for anxiety but want to get off it as soon as possible
Morphine sulphate (low dose) for pain.
Zopiclone 2-3 times a week to try and get some sleep but again, i want to get off this as soon as possible.
I will NEVER put another pharmaceutical antidepressant or mood stabiliser in my already fragile body and burnt out brain as they have all led to misery in the long run. And have long since cut all ties with the useless, harmfull and life wrecking mental health system.
Interestingly, the only time I ever feel anything close to feeling happy is when ive taken all three medications together. With my limited pharmacological understanding I have identified that opioid related endorphins from the morphine and gaba stimulation from the ativan and zopiclone may be the reason I feel better at these times. I can briefly feel love and affection again for my family, friends and my dear little dogs and “normal feelings even close to happiness.
I want to try mindlab pro partly for convenience and partly to take some of the guess work out of making my first stack. Do you think this stack is appropriate for me?or do I need to do something completely different? Also, if it is a good place to start, is there anything it’s missing that I should add (like sulbutiamine) for the specific relief my complex problems which im gonna simplify, in order of severity, here goes…..
Depression (no joy in anything, no natural lifts in life e.g. the sun shining, spending time with people I love and no motivation to do anything)
Anxiety ( debilitating enough that it controls my every movement, holds me hostage in every environment and destroys any and every attempt to lead a normal life)
Fatigue and brainfog (affecting my memory recall, concentration and makes me feel as though I have a fish bowl mechanically locked on to my cranium!!!)
Many thanks in advance, to say I am grateful for any advice/pointers you can give me is the understatement of my lifetime!! And eagerly await your reply. Blessings, Euan Mackenzie
Ps I should have said, i live In the UK and might not have access to certain products
Euan, I know how you feel because I was in that spot about 6 years ago. It took me nearly 3 years to finally get healthy again and I’m now functioning better than I ever have. So there is hope and I encourage you to keep experimenting with nootropics until you start feeling better every day.
Mind Lab Pro is great start. But you are going to need more. Use MLP as your base and build from there. Please take a look at my current stack and read each review that is linked in that post so you have a better understanding on how each works. You’ll find that list here: https://nootropicsexpert.com/what-i-take/
I do offer personal consultations as time permits if you are interested.
OK David Thank you. Once I’ll start using Mind Lab Pro for a couple of weeks I will report back to you and let you know how I’m doing.
Thank you for your help.
Thank you David for your recommendation, everything is clear. I will add Performance Lab Whole-Food Multi and DHA to my stack.
I just have one question about Magnesium L-Threonate. The dosage rate on the label is 3 capsules equal 2 g (2.000mg) per day.
At the moment I’m taking 2 capsules in the evening.
You recommend to increase my dose to 400mg per day.
What is the best way for me to do that?
How many capsules do you think I should take?
Thanks for your help.
Mick, 2 grams per day is far more than what I suggested at 400 mg per day. I’d keep on doing what you’re doing. But in the evening.
Hi David
I’m taking these nootropics at the moment
B Complex, methylcobalamin, folate
Magnesium L-Threonate
Zinc 25mg
L-Theanine
I’m also taking Tricyclic antidepressant (TCA) Nortriptyline (Allegron).
My biggest problem is social anxiety and depression. Because I’m taking antidepressant I don’t get depressed much, but social anxiety is the biggest problem for me.
At the moment L-Theanine 400mg twice a day (800mg a day) works well for me, but I’m still uncomfortable in social situations.
I would like to purchase Mind Lab Pro stack and see if it helps.
In M.L.P. there are 6 nootropics that can help with depression and 7 that can help with anxiety, and one of them is L-Theanine 100mg.
Would you please recommend how much L-Theanine I should add to M.L.P. stack?
And should I still continue using L-Theanine twice a day as I do now, or once is enough?
And could you please tell me if I need to add something to my basic stack like CDP-Choline or DHA or maybe some other vitamins?
I’m not sure about Zinc, do you think I still should be using it?
Sorry for so many questions, but you’re the only person that I know who can help me with nootropics.
Thanks
Mick
Mick, your L-Theanine dose is a little high but if it works for you then I wouldn’t be too concerned. Mind Lab Pro contains 100 mg L-Theanine so if you try it you many want to only take 400 mg L-Theanine once per day.
Zinc usage varies with age. Older guys need more zinc. But any one dosing zinc should be using 1.5 – 2 mg copper per day.
Increase your magnesium dose to 400 mg per day and take it in the evening.
Also consider adding a high quality multi to your stack. My preferred multi is the Performance Lab Whole-Food Multi for men which works well for me.
Mind Lab Pro also provides 250 mg Citicoline which may help. Definitely add 1,000 mg DHA per day.
Once you start using Mind Lab Pro for a couple of weeks report back and let me know how you are doing. And we’ll go from there. We need to be careful because of your use of a tricyclic antidepressant.
Hi David,
I started taking Mind Lab Pro (MLP) and within an hour my mood was up, I was motivated and confidant and my productivity was up. This continued for 5 days. I then added Whole Food Multi (WFM), and crashed. I stopped taking WFM but didnt improve. I have retested MLP again and it made me feel worse, lower mood, anxious and couldn’t concentrate. I am wondering if it is the folate. I am hetrozygous MTHFR C677T, numerous COMT hetroxygous, and numerous MAOA homozygous and have reacted badly to folate in the past. But I thought MLP and WFM might have been ok for me as the B12 and folate in MLP and WFM are not the methylated form?
I am ADHD and have been prescribed dexamphetamine, it works great for me, stops my racing mind, lifts my mood and confidence. But it only lasts 3 hours and I cant take it after 2pm, and have a terrible crash in the late afternoon. My doctors wont prescribe it for me anymore as they say I should not be taking it after age 50. I am desperate to find something to replace the dex. I have tried hundreds of supplements with no success. Do you know how dexamphetamine works in the brain and what I may be able to replace it with?
Thanks for your help.
Graeme, I had to think about this one and cannot give you a quick answer to what you experienced.
The folate and B12 in the Performance Lab Multi is equivalent to the methylated form to ensure absorption. But I can’t imagine the doses are high enough to cause this type of reaction. Even with your MTHFR gene issues.
As for dexamphetamine, you get a ‘terrible crash’ later in the afternoon because the stimulant forces your brain to use more dopamine. And especially in the aging brain, it runs out of dopamine much more quickly than it should. Younger guys have this problem as well. But it’s more pronounced the older you get.
May I suggest that you try the ADHD protocol I’ve been using for years that addresses exactly what you are talking about. The stack supplies dopamine, acetylcholine, improves signaling and repairs dopamine receptors. If you dose according to how I describe it in the post, you don’t crash in the afternoon. You can see that post here: https://nootropicsexpert.com/best-nootropics-for-adhd-add/
Come to think of it now, the use of Mind Lab Pro and the Whole Food Multi could have amplified how your brain is using the stimulant. Maybe the extra support I talk about in that post would help.
Hi David i bought your book and its awesome, i want to start using MindLabPro and im curious bcs to be honest i do use drugs like mdma/ecstasy/cocain like once or twice a year on music festivals. And i want to ask you if it can interfere with mindlabpro or is it save to use and if its not save then how many hours/days i have to stop taking mindlabpro before use of those substances and also how many hours/days to start taking mindlabpro after that night when ofcourse mindlab pro i ll take in the morning and other things at night. And i also wanted to ask if its problem to use performance lab sleep after that night because Performancelab sleep and also extasy/mdma interferes with serotonin. (If is something only precursor for neurotransmiters than it should be okay right?)Thank you for your answer.
Marek, you are right to be cautious and I haven’t got a simple answer. Because it depends on what the drug is and it’s specific mechanism of action.
I suggest looking up each ingredient for both Mind Lab Pro and Performance Lab Sleep. Learn their exact mechanism of action in your brain. And play close attention to the “side effects” section of each individual review here on Nootropics Expert. And do the same thing (Wikipedia) for the drugs you occasionally use. Understanding how each works will help you understand which may amplify or interact with another.
I know for certain I’ve reviewed a couple of nootropics that work well when detoxing from something like MDMA. So please use the search function top right for “ecstasy” and “MDMA” and see what turns up.
And thank you Marek for your feedback on my book Head First. It’s means a lot to me. And let’s others know that there is a real guide available now on nootropics and how to use them.
David,
Great review. What are your thoughts on taking Mind Lab Pro on an empty stomach? That is how I have been taking Mind Lab Pro for awhile, now; Primarily due to the fact that is it full of water soluble vitamins and amino acids.
I see you take yours with Coconut Oil, is there a specific reason why, as opposed to an empty stomach?
The other reason I use it on an empty stomach, is I stack the dose with 500mg of additional Tyrosine, and, I had tried Neurohacker’s Qualia Mind, and they mention to use it on an empty stomach – the ingredients are very similar.
Let me know your thoughts.
I have the same question.
Also, do you think taking the MLP within the fasting window while doing Intermitent fasting, would be ok? Or it could mess with the fasting signaling, given it has aminos and vitamins.
Thanks;.
Bernardo, MLP is primarily water-soluble amino acids and B-Vitamins. I can’t see how it would interfere with fasting on a physical level. But in theory I suppose a “fasting fundamentalist” would argue that taking anything would negate true fasting.
Hello David,
thanks for a really interesting and informative page, and the effort of helping people out! I am new to the world of nootropics but interested in how to get more out of my brain and myself. I have also trouble in concentrating and getting things done, mood swings, lack of energy, and low self esteem, which I would like to treat somehow. The spectrum of nootropics seems really wide and I am wondering, where to start. I was considering starting with Mind Lab Pro for three months and see how it works. Meaby later add something else, if it feels necessary. What do you think?
Andy, starting with Mind Lab Pro is a good idea because this stack was designed with two ideas in mind:
1. high quality ‘starter’ stack that can be used longterm
2. for the experienced neurohacker who expects results and wants to avoid buying individual supplements
I tried many different pre-formulated nootropic stacks in the last 12 years. But once I started using Mind Lab Pro I’m still with it. Because it works. And if I run out for a week I can feel it.
Start with MLP and see how you feel in a month or two. Report back with your results and we can tweak it from there.
I appreciate the fast response, David.
As I don´t live in the US and it takes quite some time to have the products delivered to the country where I live in, I won´t be able to get the True Brain in time.
However, I still have a small 3.6g packet of Alpha Brain here. I was wondering… if tomorrow (friday) I start taking the MLP consistently, but considering the heavy classes on saturday and sunday (which would be the 2nd and 3rd day of MLP) if I also take the Alpha Brain on these days, aiming on a more immediate effect, would that be ok (mixing both) ? Maybe half dose Alpha Brain each day (sat/sun)? ( I actually don´t remember trying the A.B. full dose yet) …
Then in August I might try the True Brain as well.
Bernardo, You should be able to safely add Alpha Brain to your daily stack on your two heavy days without overdoing it. Try it for a couple days and see how you feel.
Thank you and congrats for your work.
Hello, David. Thanks for the great review and all the great content on your website.
I will start taking Min Lab Pro (M.L.P.) soon and this will be my first ever nootropic (if we are not considering theanine and caffeine as nootropics…also took panax ginseng for about a month or two, years ago)
My intention for M.L.P was to take it only on intense classes days, like the MBA classes I take on some weekends/month which last all day long (Sat. and Sun.), and maybe some other days that I needed that extra push on brain performance. I do have brain fog and other brain issues that I´m already adressing with diet and some other things that are yet to be improved.
However, I noticed Mind Lab Pro (M.L.P) is not the best choice when you want a sort of an instant push on brain performance, like you may would get by taking True Brain, for instance. I was actually deciding amongst those 2 premaid Nootropics, and ended up deciding for M.L.P. as it is all natural and concidering this will be my 1st time so I didn´t want to start with racetams (like in TrueBrain).
That said, do you think I´ll benefit from M.L.P, like, if I take it next saturday/sunday which are classes days? Or it is only worth it if I take it continuously? If so, I´m considering taking like 3 days on/1 day off or so, because I always want to be extra cautious to avoid any sort of tolerance (although I do take a fair amount of caffeine thru black coffee every day).
Thank you and sorry for the long question.
Bernardo, many consider L-Theanine, caffeine, and ginseng as nootropics because they directly influence brain function. So you already have some experience with nootropics.
To get the full benefit of Mind Lab Pro, you should be using it every day. Because while the benefits are immediate, the full effect of MLP comes from using it consistently. In a month or two you may find you will not need a “boost” on your heavy study days. But until then I suggest you use Mind Lab Pro every day. And something like TruBrain that contains the racetams on your heavy study days.
Hi David,
Just received my first batch of Mind Lab Pro!
I was just wondering, should I stack this with a full B-vitamin complex or only with B1 given that vitamins B6/9/12 are already in the product? I’ve been taking a B Complex vitamin for some time but I don’t know if continued use of this would be ‘overdosing’ on B vitamins.
Also plan to stack with fish oil and magnesium as per your recommendations…I may want to try additional nootropics that are meant to help with anxiety but I’ll see how I get on with MLP first!
Thanks in advance.
Colleen, the B-Vitamin dosages in Mind Lab Pro are low enough that you can safely use a quality B-Complex without overdoing it. I do and it works great for me. Just keep an eye on the total dosages.
Hi David,
I am taking MLP for 2 weeks and I do not feel anything different than before. Do you recommend to combine it with others nootropics, vitamins, supplements, etc? to enhance MLP. In this case, which supplements do you think can help enhance MLP?
Thank you very much and congratulations for your blog, it is really helpful.
Hugo, I do recommend using additional vitamins and minerals when using Mind Lab Pro. Most of us do not get sufficient nutrients from the food we eat every day. And our body and brain require these vitamins and minerals to make things like neurotransmitters.
You could be low in any one of magnesium, iodine, selenium, any of the B-Vitamins, Vitamin A, etc. If only one or two of these critical nutrients are low there is no nootropic on earth that will help.
On the other hand, if you are in perfect health and your body is getting everything it needs everyday it’s possible that Mind Lab Pro is not the right nootropic stack for you.
Hi David
Thanks for the post I have been looking for something like this for a long time. I would say I consider myself very sound in terms of health (I am also vegetarian). However, I run 3 businesses and for a long time my only tool has been ultra marathons, Vitamin B and unhealthy doses of caffeine. I want to start using Mind Lab Pro but i notice it doesn’t have some of the nootropics in your 2018 list What are the essential add-ons to the Mind Lab Pro stack?
Nsika, great question and thanks for asking. Mind Lab Pro is a great pre-made nootropic stack to use as a base. And for the “average” person who isn’t pursuing a high-octane lifestyle like you or I.
But depending on what you are trying to achieve you may need other nootropics in addition to Mind Lab Pro. But I stress it depends on what you are working on to help cognition, memory and mood.
In my case, I’m Adult ADD and require more dopamine and acetylcholine than what Mind Lab Pro offers. So I use the stack described in my ADHD post: https://nootropicsexpert.com/best-nootropics-for-adhd-add/.
In your case I highly recommend making sure your B-Complex is all bioavailable. Using methylcobalamin and folate instead of cyanocobalamin and folic acid.
Aniracetam is at the top of many a high-achievers list of nootropics. But it needs to be stacked with Alpha GPC or CDP-Choline to get the full benefit.
Don’t beat yourself up over caffeine consumption. Please see my recent review on caffeine here > https://nootropicsexpert.com/caffeine/
DHA in a high quality Omega-3 is a must. As is a raw-food or whole-food multivitamin/mineral supplement. I’ve been using a multivitamin for years but didn’t realize until I wrote the last couple of posts how important this addition was for my body and brain.
You are even more challenged as a vegetarian. Please use the search box top right for the keyword “vegetarian” and see what turns up. There are certain nutrients you are almost certainly lacking by following this diet. Learn what you are missing in your diet and how to fix it with the right nootropic supplements.
Final word is using a high quality coconut or MCT oil 2 or 3 times per day. Your brain needs this fat and I cannot stress strongly enough what a difference this single thing can do for your cognitive health.
Hello,
Have you ever heard of Qualia? They also offer rather a complete pre-made stack, but there are a lot of ingredients. Could you maybe do a review in the future?
Kind regards
Roman, I plan to begin doing pre-formulated stack reviews sometime in the next couple of months. And Qualia is on my list to review.
Hi! i Have been using mind lab pro for 2 and 1/2 weeks but i haven’t noticing any difference! now i know it takes time to see a difference but i have a question about the dosages! Its actually to little for each nootropic! so for instance, l theanine is 100 mg if i take it every day but don’t feel anything but in the long term will I see the benefits from it or must i take a higher dose?
Mohinder, the dosages in Mind Lab Pro are high enough for a relatively healthy brain. The formula was designed so the nootropic supplements included in this stack work in synergy. To provide the kind of effect you would get if you were using much higher doses of individual nootropics.
I find that I get the best results with Mind Lab Pro when I take it with a tablespoon of unrefined coconut oil, supplemental DHA, a B-Complex vitamin and magnesium. That stack would likely help anyone using MLP. Because most of us are low in Omega-3’s, the B-Vitamin, and magnesium. Coconut oil helps with better absorption of the fat-soluble nootropics in Mind Lab Pro.
Everyone’s brain and body is different and will react differently to any nootropic stack. Including MLP. I find the changes are subtle. But have been getting more profound the longer I use it. Different forms of memory are better, I feel better, think faster, and am in a better mood. But I only notice these differences when I’m truly aware of what is going on with me and my environment.
You can double your dose of MLP every day. Two capsules in the morning and two at noon.
David, I would like to order your book and am wondering if I will receive the hard copy as well as the digital. I am also needing to know if someone is on methadone is it safe to take these nootropics. Is there info regarding this in your book.
Thanks for the wealth of information you provide.
Laura, Head First is available as a digital download with a choice of .pdf, .mobi, or .epub depending on the reading device you prefer. I’m hoping to release a hard copy of Head First as well. But it is taking awhile to put together the logistics. So for now it is digital only.
Your question about Methadone and interactions with natural nootropic supplements is important. But there is no simple answer. The best resource I’ve found so far for checking drug interactions is here: https://www.drugs.com/drug-interactions/methadone-index.html. One example I found doing a quick search is you should not use Ginkgo Biloba with Methadone: https://www.drugs.com/drug-interactions/ginkgo-biloba-with-methadone-1174-10621-1578-0.html.
I’m sure there are several others as well. Most nootropics will be safe with Methadone. But some will not. So it’s important to check every supplement you are considering by using a resource like drugs.com before you take it.
Safety is of course our highest priority here at Nootropics Expert. So my advice is get the book Head First and use the interactions list on drugs.com before trying anything.
David,
Almost 3 weeks into taking MindLabPro, 5 days a week, off sat & sun. Only taking one capsule in morning, One at noon with food. Stomach upset was no problem splitting the dose, but the effect of drowsiness, dizziness, actual loss of clear thinking or short term memory has me baffled. I thought this formula would be to my benefit. I have yet to find one nootropic that works! I am extremely frustrated. My Mother has dementia, so I am afraid I will go the same route as her.
James, that’s why we say “your mileage may vary” when it comes to nootropics. Or any dietary supplement. You’re the first person I’ve heard from who has reported a negative experience with Mind Lab Pro. Which is saying something for that stack.
Fortunately, we have a ton of research on nootropic supplements for helping dementia and Alzheimer’s. My suggestion is do a search here on Nootropics Expert for “dementia” and another search for “Alzheimer’s”. And see what turns up. You’ll be surprised at your choices. It’ll take some research on your part and the willingness to experiment. Even on yourself first. And find something that works.
It’s easier with individual supplements vs a pre-made stack because you’ll know almost immediately if something may cause a bad reaction. One thing to note is even though you are directly related, you won’t share ALL exactly the same genetic makeup. So something that doesn’t work well for one person may work well for the next. Even someone in the same blood line. Just keep that in mind please.
Hello David,
I am two days into taking Mindlab pro at the standard dose of two in the morning. Not feeling much of anything except of course a side effect. What is in this formula that would cause a stomach ache several hours after the dose in the morning and even into the evening?
Thanks
James, Mind Lab Pro does not have any type of nootropic that provides a ‘stimulant-effect’. So you’ll not ‘feel’ anything noticeable like a big burst of energy, or amped-up alertness. Most immediate changes are subtle and take a lot of self-awareness to notice. Things like improved memory, better mood, less anxiety, etc.
The most noticeable differences are after using the stack for 2 or 3 weeks. And looking back on what’s improved. For many, the improvements are profound but take awhile to realize.
Bacopa Monnieri, Phosphatidylserine (PS), Rhodiola Rosea, N-Acetyl L-Tyrosine (NALT), Pine Bark Extract, Vitamin B6, Vitamin B9 (Folate) can all cause stomach upset in some people. So it’s difficult to pin-point exactly what the culprit is in your case. It’s unlikely the B-Vitamins are the cause because the doses are small. But it could be any one of the others.
Have you tried taking Mind Lab Pro with a meal to see if that makes a difference? Or take one capsule with a meal in the morning. And the other at noon with a meal.
Hi David
i tried just yesterday 2 cap. of Mind Lab Pro and the results was amazing but, after the good effect i notice a strange situation: i feel the brain “overpowered” and for some hours i get stuck procrastinating for a bit and having brain fog and i feel the brain power but for 2 hours i can’t focus on what to do. After this “ritual” i finally starting think with a lot of focus, clarity and motivation. What’s your advice?
P.S i’m the guy with adhd of 17 years that commented your post on adhd (amazing!) and in 7 days i’ll try your stack with a low dose of ritalin
Giulio, it sounds like 2 capsules of Mind Lab Pro started working right away in boosting neurotransmitters and neurotransmission. Once your brain adjusted, things settled and the stack continued to do its job.
I think you have two options; 1. use only one capsule for a week or two until your brain gets accustomed to more nutrients. or 2. Use the dosing you’re using now and cope with the 2-hour lack of focus until your brain gets used to Mind Lab Pro. Which again, may take a week or two.
Hi David,
I want to switch My routine from ciltep + magtech from naturalstacks to mindlabpro, but i am worried about My energy level being low without the caffeine from smart caffeine, and I can’t use smartcaffeine with mindlabpro as the L-THEANINE dose will be doubled.
What is a effective subsitute with mindlabpro as a morning energy boost? (I really dislike cofee.)
Also do you think it is Good to continue with the magnesium boost from MagTech with mindlabpro?
Thanks in advance
Joakim, I don’t see a problem using SmartCaffeine with Mind Lab Pro because that would only boost your L-Theanine dose to 300 mg. Maximum dose of L-Theanine is 1,200 mg per day according to the Cleveland Clinic. So unless you are especially sensitive to supplements 300 mg should not be an issue.
And MagTech for your magnesium is a smart move as well. Your body and brain need the magnesium.
Thanks David. So do you think Vitamin B9 is doing the same job as Vinpocetine, or is it worth taking Vinpocetine alongside Mindlab?
I would continue using Vinpocetine with Mind Lab Pro. But it’s Pine Bark Extract in the formula update with MLP that replaced Vinpocetine. This extract increases cerebral blood flow along with several other advantages not shared by Vinpocetine. Please see my review on Pine Bark Extract for more detail here > https://nootropicsexpert.com/pine-bark-extract-pycnogenol/
Gotcha. Thanks David. Look forward to your updated review.
Hi David,
I just started taking Mindlab Pro. Early days yet, but seems to be sharpening me up. I notice, however, that they’ve recently changed the formula. Vinpocetine has been replaced by vitamin B9, and pterostilbene with maritime pine bark.
I’ve seen some conflicting opinions on pterostilbene, but I’ve read nothing but good things about vinpocetine. I guess time will tell whether vitamin B9 does the same job, but what’s your take on this? Are you still using MLP, and have you noticed a different effect following the formula change?
Oscar, Vitamin B9 (folate) is ‘required’ for making dopamine, epinephrine, norepinephrine and serotonin in your brain. In my humble opinion this makes it a required ingredient in any pre-made nootropic stack. You need folate to work synergistically to make some of the other nootropics in the stack work.
The other formula change to include Pine Bark Extract was a great decision as well. I love Vinpocetine. But it’s a prescription drug in some parts of the world. Which means Opti Nutra couldn’t ship Mind Lab Pro to those countries. And there is strong talk in the USA of taking Vinpocetine off the supplement market because of claims by a large pharmaceutical that they have first dibs on selling it as a drug.
I’ve been using Mind Lab Pro daily for about 2 years. And I was just thinking this morning about how much better my memory is now compared to just a year ago.
I’ll be updating my Mind Lab Pro review soon to reflect changes in the formula. So thanks for the reminder! 🙂
will you give it to chidren?
my daughter is 10 years old and do have concentration problems in school which in turn affects her grades
my idea is to start her on 1 pill a day. as it is all natural products can there be any harm. I am from south Africa and the ease with which our local doctors prescribe Ritalin makes me uneasy
I did contact the mlp help desk and they said that they did not test it on children so legally they are not willing to recommend it for children
any advise will be appreciated
Marcel, I would give Mind Lab Pro to my child because there is nothing in this formula that would interrupt a child’s normal cognitive development in a detrimental way.
I completely understand the company’s reluctance to advise you either way simply from a legal standpoint. They are correct in that nearly all clinical trials on most of the nootropics on Nootropics Expert are done with older people fighting some type of disease. All we can do is extrapolate the findings of these studies to determine if they would help a healthy person.
I’m reluctant to advise you either way as well for legal reasons. Because I’m not a doctor. Don’t even play one on TV. But I would give one capsule a day to my child.
Hi
I’m taking CILTEP, not very impressed.
I can take MindLabPro, but what do I stack with if I wish to improve thinking, social, energy and motivation.
Thx
Enrique, Mind Lab Pro will go a long way in helping you with thinking, social, energy and motivation. I’ve tried a lot of pre-made stacks. And Mind Lab Pro is the best ‘base’ stack by far.
Please take a look at this post I put up in January 2017 on New Years Resolutions. In particular, go to this section > https://nootropicsexpert.com/7-nootropics-secrets-to-keep-your-2017-new-years-resolutions/#motivation. And scroll down through the other sections on memory, energy and anxiety. You’ll have plenty of options to choose from to stack with MLP.
Notice in that post that the nootropics in green font with an asterisk (*) are already included in Mind Lab Pro. I’ve added Aniracetam, ALCAR, NALT, and Sulbutiamine to my MLP dose. And it works great for me. Good luck and let me know what you end up choosing that works best for you.
David, thanks for your review! Even before reading your review, I had decided to try MindLabPro, for myself and for my 90 year old mother who has been showing some symptoms of cognitive decline (primarily short term memory) during the past 6 months or so. I hope it works well! I will also mention MindLabPro to her homeopathic M.D. next week. Thanks again!
Thanks Bob. MindLab Pro is the best pre-made stack I’ve used so far. And I’ve tried a lot of them. Wishing you the best with your Mom. My primary doctor was impressed (to say the least) with NootropicsExpert.com. So thanks for visiting. And please share this with your friends too.
Hello,
Have you ever heard of Qualia? They also offer rather a complete pre-made stack, but there are a lot of ingredients. Could you maybe do a review in the future?
Kind regards