Table of Contents
Key Takeaways
- Noopept is a potent cognitive enhancer with various benefits for memory, learning, perception, and mood.
- It differs from traditional racetam compounds but still produces similar effects.
- It is up to 1000 times more potent than Piracetam and offers additional benefits, such as lower effective doses and influencing memory consolidation and retrieval.
- Noopept is considered safe within the recommended dosage range of 10 – 30 mg per day.
- In the USA, the best place to buy Noopept is Cosmic Nootropic – Noopept or Science.bio-Noopept Powder or Science.bio-Noopept Solution
Noopept (n-phenylacetyl-l-prolylglycine ethyl ester or GVS-111) is an ampakine nootropic similar in action to the racetam-class of compounds. Noopept is up to 1000-times more potent than the original racetam, Piracetam.
Noopept was patented by Russian-based pharmaceutical company JSC LEKKO Pharmaceuticals in 1996. Research shows Noopept has similar effects, but works differently than other nootropics in the racetam-family.
Noopept is not considered a true “racetam” because it doesn’t have a 2-oxo-pyrrolidine core.
Noopept does not appear in blood samples when taken as a supplement. Instead it elevates concentrations of cycloprolylglycine (CPG) in the brain.[i]
CPG is a dipeptide consisting of proline and glycine which acts as a modulator of acetylcholine transmission and AMPA receptor function.
Noopept is patented in both Russia and the USA. It is sold as a prescription drug in Russia, and other countries that were part of the Soviet Union. And as a supplement in the United States.
Neurohackers use Noopept to boost cognition, memory and learning. And to improve reflexes, perception, logical thinking and mood.
Noopept helps:
- Brain Optimization: Noopept increases Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). Critical for neuroplasticity and Long-Term Potentiation. Brain health gets a boost along with long-term memory.
- Neuroprotection: Noopept prevents the release of excess glutamate in your brain. Glutamate is the brain’s primary excitatory neurotransmitter. When there’s a lack of oxygen in the brain, neurons can’t receive glutamate. This leads to toxic levels of glutamate within brain cells. And can result in neuron damage and death. Diminishing this neurotoxic overload with Noopept is potent neuroprotection.[ii]
- Brain Waves: Noopept boosts Alpha and Beta brain wave activity. You become calmer and more creative. It’s easier to go into a flow state. And you are prone to making innovative and resourceful decisions.
Overview
Noopept (nphenylacetyllprolylglycine ethyl ester or GVS-111) is often included in the racetam-family of nootropic compounds. But is not a true “racetam” because it does not have a 2-oxo-pyrrolidine nucleus.
Noopept was developed in Russia where it is called Ноопепт or GVS-111. Russian-based pharmaceutical company JSC LEKKO Pharmaceuticals synthesized Noopept in 1996 based off the endogenous neuropeptide cycloprolylglycine (CPG).
Researchers in Moscow found Noopept similar to Piracetam in not only it’s nootropic effect, but also anxiolytic activity.[iii]
Noopept is a water-soluble ampakine nootropic. AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic) refers to one of three glutamate receptors in your brain.[iv]
Noopept could also be considered a Cholinergic compound because it affects acetylcholine levels in the brain.
One of the newer synthetic nootropic compounds, Noopept is known as a cognitive enhancer. And is known for its anxiolytic, or anti-anxiety effects.
As a cognitive enhancer, Noopept is considered to be up to 1000-times more potent than Piracetam. As an ampakine nootropic, it helps increase attention span, alertness and boosts all three levels of memory. Memory formation, retention and recall.
Ampakines tend to have a stimulant effect. But do not produce the same stimulant side effects as Ritalin or coffee from prolonged use.
Noopept vs. Piracetam: What’s the Difference?
Russian-based pharmaceutical company JSC LEKKO Pharmaceuticals developed Noopept in the late 1996 as a peptide analogue of the original nootropic Piracetam.[v]
Noopept and Piracetam are both water-soluble. And both Noopept and Piracetam are cognitive enhancers. Both have neuroprotective and anxiolytic (anti-anxiety) qualities.[vi] Both racetams are able to improve learning and memory. And both are able to repair brain damage.
But Noopept has additional benefits not shared with Piracetam. First, the effective dose of Noopept compared to Piracetam is 1,000-times lower. A typical dose of Noopept is 10 – 30 mg while Piracetam is often dosed up to 3 or 4,000 mg.
Second, Piracetam facilitates only the early stages of the memory process. On the other hand, Noopept influences memory consolidation AND retrieval steps as well. But if someone claims “is Noopept a stimulant” it’s simply not true.
So Noopept helps you develop the memory, retain the memory, and then recall what you have stored in memory.[vii]
Noopept also has additional selective anxiolytic (anti-anxiety) action. Researchers believe this is due in part to Noopept’s antioxidant effect, anti-inflammatory action, and the ability to prevent the neurotoxic effect of too much calcium and glutamate.
How does Noopept work in the Brain?
Noopept boosts brain health and function in several ways. But two in particular stand out.
- Noopept modulates AMPA and NMDA receptors and acetylcholine (ACh) transmission. Noopept boosts the level of cycloprolylglycine (CPG) in the brain. CPG is a dipeptide consisting of proline and glycine which acts as a modulator of acetylcholine transmission, and AMPA and NMDA receptors.
When brain cells are starved of oxygen, glutamate which is your brain’s primary excitatory neurotransmitter, does not work efficiently with neuroreceptors. The result can be a toxic buildup of glutamate within brain cells. Causing neuron damage and ultimately, neuron death.
Noopept modulates neuroreceptor function keeping glutamate transmission at normal levels. Protecting neurons and other brain cells from glutamate damage.
Noopept has also been shown to modulate acetylcholine flow in your brain. Restoring the harmony of glutamate and acetylcholine function not only protects your brain from damage. It can boost cognition, memory, learning, recall, mood and relieve anxiety.
- Noopept increases Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and mRNA. NGF and BDNF are directly related to neuroplasticity. This ability to repair and even grow new brain cells can have profound implications. Particularly with someone with neurodegenerative brain damage like Parkinson’s or Alzheimer’s. And even affecting Long-Term Potentiation needed for long-term memory development.
mRNA affects the expression of genes and intracellular communication in brain cells. This ongoing brain signaling and gene expression within brain cells is required for healthy cognition.
One study conducted in Moscow showed long-term use of Noopept boosted NGF, BDNF and mRNA. The animal subjects in this study showed no sign of tolerance. And long-term use of Noopept even potentiated the neurotrophic effect.[viii]
How things go bad
Glutamate is an excitatory relative of GABA. While GABA has a calming effect, glutamate stimulates. Glutamate is the most common neurotransmitter in the central nervous system.
But glutamate can be toxic to neurons. And too much of it in your brain can kill brain cells. Lou Gehrig’s Disease for example, is caused by excess glutamate.
But glutamate is a pivotal neurotransmitter in the brain. It links the brain circuits involved in memory, learning and perception.
↑ Too much glutamate can kill neurons
↓ Too little glutamate can cause problems with memory, learning and perception
↓ Acetylcholine levels decline
↓ Nerve Growth Factor declines
↓ Brain-Derived Neurotrophic Factor declines
All of these changes can happen at any age. And are a product of the food we eat, what we drink, lifestyle habits, the air we breathe and more.
So Noopept can help for age-related cognitive decline, as well as a student looking to do better in school. By boosting NGF, BDNF and acetylcholine, and controlling glutamate in the brain.
Noopept benefits
Noopept modulates AMPA and NMDA receptors. AMPA receptors are associated with how glutamate and calcium is used in your brain. As a neuroprotective agent Noopept, it’s more of a neuroprotective role.
Similar to the AMPA receptor, the NMDA receptor is also associated with glutamate and calcium use in your brain. They work together to modulate how neurons use glutamate.
Noopept modulates levels of glutamate within and between neurons. It prevents glutamate toxicity, and influences Long-Term Potentiation (LTP). LTP is associated with neuroplasticity that allows long-term memories to form.
There is clinical evidence that Noopept boosts communication and neuron signaling. By boosting Alpha and Beta brain wave activity. You become calmer and more creative. It’s easier to go into a flow state. And you are prone to making innovative and resourceful decisions.
Noopept produces an anxiolytic (anti-anxiety) effect. It stimulates dopamine receptors (D2 and D3) and acetylcholine nicotinic receptors. And Noopept also seems to modulate some serotonin receptors. All contributing to a better mood and less anxiety.
Noopept has been shown in the lab to boost Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). NGF and BDNF are both involved in neuroplasticity, and the repair and replacement of damaged brain cells. Resulting in overall better brain health, memory and cognition.[ix]
Noopept is water-soluble and quickly enters your brain after you take it. Once in your brain, it boosts signal transmission, and protects neurons.
How does Noopept feel?
Nootropics users report:
- Noopept as a study aid. On its own, Noopept increases focus and attention for many neurohackers. Mental arithmetic and grasping difficult concepts is easier.
- Increased verbal fluidity. Your conversation skills could increase with Noopept. Vocabulary comes easier. Being able to focus contributes to a more balanced dialogue. Neurohackers report being more outgoing, friendly and less self-conscious.
- Improved mood. With Noopept you may find yourself better able to deal with stressful situations and work issues that normally get you down. Once you get past the first few weeks of unpleasant memories related to PTSD you may find overwhelming emotions will subside. You could feel detached in a pleasant way from painful memories.
- Music appreciation. Many users report increased pleasure when listening to music while using Noopept. For some it takes music to a different plane. Distinguishing between instruments in sound tracks is easier. As a whole, music sounds better.
- Long-term memory. Noopept affects NGF and BDNF which affects long-term potentiation. Some neurohackers report memories long forgotten suddenly spring up. Which could be good or bad I suppose depending on the memory. But reports say memories are clear. And if they’re unpleasant there is an emotional detachment shielding from unpleasant feelings.
You should be able to experience the effects of Noopept soon after you take it. It’s water-soluble and enters your cells quickly especially if you take it sublingually.
A word of caution however; don’t go over the recommended 10 – 30 mg per day dose! You will not experience any added benefit, and could bring on unwanted side effects.
There is some debate on the water-solubility of Noopept. It’s not truly fat-soluble but it certainly doesn’t hurt to use a quality “good fat” when taking your Noopept dose.
Noopept Clinical Research
Noopept increases Nerve Growth Factor & BDNF
A study published by the Russian Academy of Medical Sciences in Moscow shows that Noopept stimulates Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF).
In this study, researchers studied the effect of single and long-term treatment (28 days) of Noopept. They found that one-time treatment boosted mRNA in the cerebral cortex of rats. mRNA is a molecule in brain cells that carries codes from DNA where they specify the amino acid sequence of proteins.
And long-term treatment of Noopept increased Brain-Derived Neurotrophic Factor (BDNF). The researchers speculated that this sequence of events in the brain plays a role in the restoration of neurons.
Improving neurotrophic synthesis in the hippocampus boosts cognitive function. Particularly consolidation and delayed memory retrieval.
The research team concluded that Noopept “holds much promise to prevent the development of Alzheimer’s disease in patients with mild cognitive impairment”.[x]
Noopept boosts Brain Waves
Researchers in Moscow studied the effects of injecting Noopept in rats to see how it would affect brain waves.
The team found that Noopept increased Alpha and Beta brain wave activity throughout the brain.
You experience Alpha waves as you become more relaxed. Alpha waves are associated with super-learning, flow state and joy. Beta waves are associated with concentration, alertness and cognition.
The researchers observed that NMDA receptors were involved with a single injection of Noopept. While AMPA receptors were activated after longer-term use of Noopept.[xi]
NMDA receptors are associated with Long-Term Potentiation (long-term memory) and neuroplasticity. AMPA receptors are associated with increased brain signaling activity. Boosting cognition and memory.
Noopept improves memory
Noopept is known within the nootropic community to enhance cognitive function and memory. And dozens of studies support this claim of better memory when using Noopept.
One study done at the Russian Academy of Medical Sciences in Moscow conducted animal studies, experimenting with Noopept on rats. The animals were trained in passive avoidance response.
The animal’s ability to both form a memory and retain a memory was impaired. But once the rats received a dose of Noopept, they were able to retain a memory and retrieve that memory later.
In other words, their cognitive functions improved. Noopept normalized learning capacity in animals that had damage done to their cerebral cortex. And promoted training ability in rats who started with a hereditary learning deficit.
The researchers noted that “Noopept improves all three stages of memory”. And was most pronounced in those with impaired memory function.[xii]
Another study, again done with rats noted that Noopept stimulated learning after just a single administration. And repeated administration actually increased the number of successful learners among the animals who failed the initial training.[xiii]
Noopept Dosage
Recommended Noopept dosage is 10 – 30 mg per day.
Noopept is very bioavailable and easily crosses the blood-brain barrier.[xiv]
Noopept is sold in tablet, capsule and powder form. Tablets and capsules are usually 10 mg each.
Noopept is primarily water-soluble nootropic, but won’t easily dissolve in water or juice. So it may help if you take it with a meal containing healthy fats. Or with a tablespoon of extra virgin, expeller cold-pressed coconut or olive oil. Or other similar healthy fat to ensure quick absorption.
For even quicker absorption you can use Noopept sublingually. Let the tablet or powder dissolve under your tongue so it can go straight into your bloodstream, and into your brain. Bypassing your digestive system completely.
Noopept Side Effects
Is Noopept safe to use? Noopept is a synthetic nootropic and consider non-toxic. So is considered well-tolerated and safe. As long as you stay within the recommended dosage.
Side effects are rare but can include fatigue, headaches, insomnia or stomach upset. Side effects are often a result of unusually high doses of the nootropic.
Recent research has found that Noopept promotes the level of the Hypoxia-inducible factor 1 (HIF1α) protein. This action helps increase oxygen supply to areas where oxygen levels are low. But it also means that increasing the oxygen supply to tumor cells helps those tumors to proliferate. So, if you have cancer of any kind you should not use Noopept.
Headaches from using Noopept typically happen when you forget to combine it with a good choline supplement. Headaches are often a symptom of a choline deficit in your brain.
Where to buy Noopept
Noopept is sold in tablet, capsule and powder form. Tablets and capsules are usually 10 mg each.
In the USA, you can buy Noopept from Cosmic Nootropic – Noopept
And you can also get Noopept powder or liquid from Science.bio, who have just opened their store again. Science.bio-Noopept Powder or Science.bio-Noopept Solution who sell Noopept as a “research” compound. It is sold to be used in an academic laboratory research setting. They go on to state “nothing we sell is intended for nor is it manufactured for diagnostic or therapeutic purposes in humans.”
In Russia and some other Eastern European countries, Noopept is a prescription drug.
Frequently Asked Questions
How does Noopept make you feel?
Students who use Noopept as a study aid say it helps them with focus and attention. Mental arithmetic and grasping difficult concepts is easier. Many say Noopept helps with verbal fluidity. They report being more outgoing, friendly and less self-conscious.
With Noopept you may find yourself better able to deal with stressful situations and work issues that normally get you down. Many users report increased pleasure when listening to music while using Noopept. And Noopept seems to help reconnect brain circuits so it is easier to remember long-lost memories. And I personally find that when I use Noopept, I’m more productive.
Does Noopept actually work?
Noopept really does work. See the section above on How does Noopept feel? And see what real users say about their experience with Noopept for studying, listening to music, improving verbal fluidity, and putting them in a better mood.
Is Noopept legal in America?
Noopept has not been approved by the FDA in the USA as a dietary supplement. So supplement bottles will often say the contains contain a “research compound”. It is NOT illegal to buy or own Noopept in America.
Is Noopept a banned substance?
Noopept is not a banned substance in America. Neither has it been approved by the FDA as a dietary supplement. Noopept has not been “scheduled” in Australia, is available OTC in Brazil, but Noopept may be held up in customs in Canada, and so on. For other countries around the world, see my article Are Nootropics Legal in My Country?
Nootropics Expert Recommendation
Noopept 10 – 30 mg per day
I recommend using Noopept as a nootropic supplement.
Your body does not make Noopept on its own. So to get its benefits you must take it as a supplement.
Noopept is especially helpful for those looking to boost cognition, memory and recall. This nootropic helps boost the activity of acetylcholine in your brain. It modulates glutamate receptors which normalizes optimal neurotransmitter function. And increases Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF) which helps the neuroplasticity needed for Long-Term Potentiation.
Noopept is also particularly useful to students and executives who want to boost cognition, learning and memory. My experience using Noopept shows it helps boost study scores, workflow, learning and memory.
Noopept also helps improve verbal fluidity and sociability. Words seem to come easily, and vocabulary you didn’t know you had access to come into play.
Music sounds richer and fuller, and your listening experience enters a new level of music appreciation.
You should stack Noopept with a good choline supplement like Alpha GPC or CDP-Choline. It helps boost neural acetylcholine, so demands the presence of more choline in your brain.
You should not exceed Noopept doses of more than 30 mg per day. This nootropic supplement is highly bioavailable and passes through the blood-brain barrier quite easily. Start with 10 mg and see how you respond.
In the USA, you can buy Noopept from Cosmic Nootropic – Noopept
And you can also get Noopept powder or liquid from Science.bio, who have just opened their store again. Science.bio-Noopept Powder or Science.bio-Noopept Solution
Join The Discussion - 210 comments
Marcie Webber
August 16, 2021
David u r so kind answering me back and info for dosing. I am fine tuning my several pills here while recuperating from my recent surgery. Today I took 2 caps MLP, 1000mg Ani and 10mg Noopept @ 8A when I woke up.
Went to sleep at 12n. No HA but sleepy and woke up just before 2p to dose a second last dose: 500mg Ani from HR, Noopept 10mg SL from Super Smart and CDP 300mg Nutricost and dose of Vinpo 10mg from LE (noon dose) w/c am taking TID.
Am not sure what effects am getting from racetams. Vinpo feels good kind of clear thinking. Will attempt to give time manipulating these supplements to work and finish supply. Got lots. Will reveal next time attempting all these to go in my system & will ask ur advice if I stack them right. 4 sets: 1st group 1st thing in AM when I wake up 7-8a, 2nd mid AM 10 or 11am (counting this as morning dose) 3rd: 2p Early PM 4p?? then evening and last is HS Sleep. Needed the groupings to not overwhelm swallowing them.
Love u David for your kind attention to this aged woman desperate to heal my broken aged brain. God bless u. Marcie
David Tomen
August 18, 2021
Marcie, sometimes the effects of some of these supplements can be subtle and will build over time. One thing you can do is check the “How does _______ feel?” section for each supplement review. That will give you a good indication on what benefits to watch out for when trying something. Because you can rely on the experience of others.
Marcie Webber
August 1, 2021
Noopept in HR is 30mg. Not sure if it is one pill like Ani where it says 1000mg but actually it is a 500mg caps. Can you comment on this?
Now i know from the comments section, noopept not necessary to cycle it. It’s fat soluble and must have CDP/Alpha GPC to work its best. Amt of choline, go trial and error as YMMV. Dose AM & Noon & mid PM if taking TID max 30mg /day.
Combining Nopopept with Aniracetam, will 300mg CDP enough for both or experiment again? Or take Alpha and CDP dosage as recommended? What i mean a 300mg Alpha u recommend will also be same dose with CDP.
Am I understanding it correctly? Maybe one needs be higher & which one?
Does Ani needs to be recycled?
I planned to take them both BID together, both fat soluble. Will start low dose 10/10 & 500/500 respectively. Of course one at a time.
Also in Nootropics what does it mean in dosing schedule when it says AM & early PM and mid PM? and first thing in the morning.
David Tomen
August 2, 2021
Marcie, HR Supplements Noopept is 30 mg Noopept in one capsule which means you can use it only once per day. Not ideal but I’m using it and it seems to be working just fine.
Dosage of Alpha GPC or CDP-Choline is usually 300 mg with Noopept + Aniracetam. But you may find you need to double your choline dose. Only way to determine that is trial and error and how you feel.
Dosing 3-times per day typically means 8 AM, noon and 4 PM. You do not need to get the timing exactly spot on of course. Those are general guidelines.
Some find they need/want to cycle Aniracetam. I never have and it works great for me. And I’ve been using twice per day for years. Again, that is an individual thing and you need to figure out what works best for you.
Noah
December 8, 2021
Hi, David! Are the HR supplements 30mg noopept in capsules able to be opened to pour/take powder under the tongue/possibly with half the pill at a time?
David Tomen
December 9, 2021
Noah, you can use Noopept sublingually.
Stasya
June 6, 2021
Hi David, I’m starting stack with Noopept , but couldn’t find it in 10 mg, only 30. I’ve taken 30 mg by itself for a course, loved it. So now I’m prepping for my exam and overall want to be very focused and also get anti-anxiety benefits of this stack. So would it be okay with 30 mg instead 10?
10mg Noopept
750mg Aniracetam
300mg Alpha GPC
200mg Sulbutiamine
David Tomen
June 6, 2021
Stasya, 30 mg Noopept is fine but that is the maximum amount per day that you should use. Don’t go any higher than that.
Stasya
June 15, 2021
David, hi again. I forgot to ask since I’m stacking first time and didn’t try any of othe in stack nbut noopept, should I take all pills from stack at once or spread among the day like morning evening etc?
Thank you
David Tomen
June 16, 2021
Stasya, if you have not used the other supplements I suggest you try them separately first to see how you react to them.
But Aniracetam, Alpha GPC and Sulbutiamine should be used twice per day because they have a short half-life.
Aurélie
May 5, 2021
Hi David, this is the second day I’m taking noopept. Only 10 mg. Yesterday, it made me tired and depressed, but today I’m high and cannot stop laughing.
Kind regards
David Tomen
May 5, 2021
Aurélie, Noopept boosts Alpha and Beta Brain Waves as well as serotonin to certain degree.
Did you use a choline supplement with Noopept? Or did you take it on its own?
Aurélie
May 6, 2021
Thank you David. I’m taking phosphatidylcholine from Natural Factors (3 softgels = 1260 mg) at breakfast. Shall I take Alpha GPC or CDP Choline as well?
On this third day things are back to normal. Neither depressed, nor high.
And on your list: https://nootropicsexpert.com/13-nootropics-to-boost-bdnf/
I take: ashwagandha, bacopa, DHA, ginseng, l-theanine, magnesium L-threonate, rhodiola and turmeric. Too many?
My father died of Alzheimer’s disease 10 years ago. I am scared and want to protect my brain! Shall I add lion’s mane?
Best regards
Aurélie
David Tomen
May 6, 2021
Aurélie, you are not taking “too many supplements”. Use what works for you.
I am convinced that if you used 750 mg Turmeric (95% Curcuminoids) 3-times per day with 10 mg BioPerine each time for the rest of your life you would avoid Alzheimer’s altogether. See my research on Turmeric and Alzheimer’s in this article to see why: https://nootropicsexpert.com/best-nootropics-for-the-aging-brain/
Kenny
March 3, 2021
is noopept dangerous because it affect nmda receptor, will it cause Anti-NMDAR Encephalitis, some of symptoms of Encephalitis is short-term memory loss and some users report noopept cause it, too. please tell me know cause it have buy it but i’m very hesitate to use it
David Tomen
March 3, 2021
Kenny, Noopept modulates AMPA and NDMA receptors. It is considered well-tolerated and safe. As long as you stay within the recommended dosage.
Kevin
March 3, 2021
thank for your reply, David Tomen, i will stay at 10-20 mg/day, with 2-3 day off/ week, i saw a lot of users benefit from that dose and had no harm for long-term used.
Rhiannon
October 29, 2020
Hi, David!
I contacted you under a MindLab category a month or so ago. I have since purchased everything from the ADHD list and have been building and tweeking my stack. The full list seems to be a little much for me so through process of elimination I now take Mindlab Pro (which I’d already been taking for 2 years), Performancelab’s energy and women’s multivitamin, and DHA everyday. I take aniracetam 2-3x per week because taking it everyday was making me feel a bit strung out — I’m now taking 500mg once or twice per day when I do take it rather than the full 1500mg per day. I also microdose psilocybin roughly 1-2x per week (as needed) when not on aniracetam. The psilocybin seems to have a strong, positive effect on my depression.
I was hoping you could guide me a little bit as I’m hoping to add noopept to my week somehow, and I’m also in search of something to replace aniracetam for my wife. My wife actually experienced an allergic reaction to aniracetam (she’s been taking my same stack) and now needs something else that’ll boost her mood and improve her social anxiety. I browsed your site and thought noopept might be the right move for her, as it’s not considered a racetam. I’m also in search of something that will improve access to past memories and improve my interest in school work and forming/retaining new memories — hoping noopept will do the job. I’d prefer something that I could take daily as I do struggle with mood, outlook, organization, and motivation these days despite the added supplements. I have an extremely difficult time structuring my day, lifting myself out of brain fog, starting and completing tasks… I get overwhelmed easily and often feel defeated before I even start my day. This has been an issue for years and taking adderall was the greatest help I’ve had, but it didn’t feel sustainable long-term because of its effect on the heart and the side effects I was experiencing.
Hoping to get your advice. Thanks!
David Tomen
October 29, 2020
Rhiannon, Noopept might be your answer. Because it’s an ampakine nootropic. Which you need to activate the dopamine/reward/motivation pathway which I explain here: https://nootropicsexpert.com/hacking-motivation-with-nootropics/.
But make sure you are using at least 300 mg Alpha GPC or Citicoline because Noopept needs it to experience its full benefit.
If your wife reacts badly to Aniracetam she likely will to Noopept as well. You can try it but don’t be surprised if it doesn’t work for her. Instead, she could try Rhodiola Rosea: https://nootropicsexpert.com/rhodiola-rosea/
Dana
August 13, 2020
I am using 15 mgs of noopept from monday to friday once in the morning and once in the afternoon. should i take l-tyrosine also once a week or twice a week to boost dopamine production since noopept releases some of it? or is that not how it works? thanks
David Tomen
August 14, 2020
Dana, Noopept potentiates dopamine D1 and D2 receptors which can make the existing dopamine in your brain more effective. You would only supplement with L-Tyrosine if you thought your dopamine levels were low. And if you do decide to use L-Tyrosine you would use in daily and twice per day.
Adam
December 4, 2019
Hi David, im having a hrad time finding a good online source to buy Noopept. do you have a safe reliable source to buy this?
thank you for your hard work on these articles!
David Tomen
December 4, 2019
Hi Adam, I just updated this review with my preferred place to buy Noopept. It’s HR Supplements in Pheonix, AR. I use some of their racetams including Noopept and it’s quality product. Even have a QR Code on the bottle label that you can scan for a current Certificate of Analysis.
Scroll up to the “Available Forms” section and you’ll find the link to their Noopept capsules. They also offer it in powder form if you prefer.
Bevca
October 18, 2020
Thanks so much for your work on this website! Any other noopeptsource suggestions? … It’s been out of stock at HR Supplements.
David Tomen
October 20, 2020
Bevca, HR Supplements are the only company I ‘trust’ for noopept. But if they’re out of stock your next best option is Axon Labs “Pioneer” stack which contains noopept.