L-tyrosine dosage child

Tyrosine

David Tomen
Author:
David Tomen
15 minute read
Tyrosine enhances working memory, executive function, creative flow states, stress reduction, better mood, anti-anxiety and lessens symptoms of ADHD  

Key Takeaways

  1. Tyrosine boosts working memory, executive function, and creativity.
  2. It aids in stress reduction, mood improvement, and anxiety alleviation.
  3. Tyrosine lessens symptoms of ADHD.
  4. L-Tyrosine is a crucial precursor for catecholamine neurotransmitters​​.

L-Tyrosine is the master precursor required to form all catecholamine neurotransmitters.

Your brain uses the enzyme tyrosine hydroxylase to convert L-Tyrosine into L-DOPA. Decarboxylation of L-DOPA results in synthesis of the neurotransmitter dopamine.[i]

Once converted into dopamine, the enzyme dopamine-beta-hydroxylase converts L-DOPA into norepinephrine (noradrenaline).

And Phenylethanolamine n-methyltransferase converts norepinephrine into epinephrine (adrenaline).

This triad of neurotransmitters are collectively known as “catecholamines”.

Tyrosine can be a highly effective nootropic for boosting cognitive function. And is particularly helpful in maintaining cognitive performance when you’re under practically any kind of stress. Including music played above 90 dB’s.

L-Tyrosine works in synergy with stimulants like methylphenidate (i.e. Ritalin).[ii] Drugs like Ritalin work by blocking the reuptake of the neurotransmitters dopamine, and norepinephrine. And if there’s not enough dopamine available to do the job, Ritalin doesn’t work very well. L-Tyrosine potentiates increases in extracellular dopamine.

L-Tyrosine also stimulates the production of thyroid hormones T3 (triiodothyronine) and T4 (thyroxine) which are crucial in maintaining both overall physical and cognitive health.

L-Tyrosine can boost libido, memoryfocusconcentration, mood, offers anti-depressant effects, and improves executive function in those with ADHD.

Tyrosine helps:

  • Cognitive Stress. L-Tyrosine produces the catecholamine-triad of neurotransmitters dopaminenorepinephrine, and epinephrine. Sleep deprivation and extreme stressors like heat and cold can deplete catecholamine levels. L-Tyrosine restores them to preserve optimal cognition.[iii]
  • Neurotransmitters. L-Tyrosine is a required precursor for dopamine, norepinephrine, and epinephrine. As your dopamine levels increase, you’re better able to concentrate, organize your thoughts, and stay productive.
  • Attention Deficit Disorder (ADHD). L-Tyrosine can be an effective treatment for ADHD symptoms. It works in synergy with pharmaceutical drugs like Ritalin and Adderall by boosting extracellular levels of dopamine. Helping these drugs be more effective. And mitigating side effects like crashes when the drug wears off.

Overview

Your brain converts L-Tyrosine to L-DOPA which then produces the neurotransmitter dopamine. The unused dopamine is then further converted into the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). This triad of neurotransmitters are collectively referred to as “catecholamines”.

l-tyrosine reviews“Tyrosine” is derived from the Greek word tyros, meaning cheese.  It was first discovered by German chemist Justus von Liebig in 1846 in the protein casein from cheese.

Tyrosine is considered a non-essential amino acid because it can be synthesized in your body from phenylalanine. Which is found in many high-protein foods such as poultry, fish, dairy, nuts, soy products, lima beans, avocados and bananas.

L-Tyrosine amino acid supplementation enhances working memory and executive function in the prefrontal cortex. It helps with creative flow states, is fuel for inspirationcognitive flexibility, and the kind of “convergent thinking” you do in multiple choice exams.

L-Tyrosine assists in the production of thyroid hormones T3 (triiodothyronine) and T4 (thyroxine) which are crucial in maintaining both overall physical and cognitive health.

L-Tyrosine vs N-Acetyl L-Tyrosine (NALT): What’s the Difference?

N-Acetyl L-Tyrosine (NALT) is the amino acid L-Tyrosine with an acetyl group added. When you take NALT as a supplement, it breaks down in your kidneys back into L-Tyrosine. So in theory, the two supplements offer the same benefits.

There is some debate in the nootropics community on which is more effective. NALT or plain L-Tyrosine. NALT is a more soluble form of L-Tyrosine so it should be more bioavailable to your body.

However, some studies report that in some cases, a sizeable percentage of supplemental NALT is excreted in urine before it’s converted into L-Tyrosine.[iv]

On a personal note, I haven’t had any issues using NALT as a source of L-Tyrosine. It gives me a dopamine and adrenal boost you’d expect from supplementing with a dopamine precursor.

But when I haven’t any NALT around I successfully switch to L-Tyrosine although at a slightly higher dose.

When dealing with ADHD/ADD, L-Tyrosine is particularly effective when stacked with ALCAR (Acetyl-L-Carnitine). ALCAR easily crosses the blood-brain barrier for boosting acetylcholine levels. And seems to positively influence serotonin levels. And Tyrosine provides my brain with the dopamine it needs to mitigate symptoms of ADHD/ADD.

I find that L-Tyrosine stacked with 20 mg of Ritalin twice a day works particularly well. Clearly, this brain doesn’t have the capacity to produce enough dopamine on its own. And needs the boost that comes from supplementing with Tyrosine.

So like all nootropics, YMMV. Always take into account how each nootropic works synergistically with others in your stack. And how they work with any meds you need to take.

This is as much art as it is science. And experimentation is key for optimal cognition.

L-tyrosine dosage

How does L-Tyrosine work in the Brain?

L-Tyrosine boosts brain health and function in several ways. But two in particular stand out.

  1. L-Tyrosine improves memory and cognition under acute stress. Acute stress is defined as short-term stressors that can affect cognition. Examples are extreme heat or cold. Things like cold showers, extreme sports, car accidents, relationship problems, intense movies, business deals gone awry, exams and war zones.

In one study done at the University of Bedfordshire in the UK, the effect of L-Tyrosine on cognitive performance was measured before an exercise task.

Researchers recruited 8 soccer players. And had them complete a 90-minute soccer simulation performance test in an environmental chamber set at 77 degrees Fahrenheit.

The soccer players were given either L-Tyrosine before exercise or a placebo. Cognitive performance was measured before the exercise task. Then again at “half-time”, following half time, and following the entire simulation.

The cognitive performance task assessed dual-task and vigilance. The outcome revealed that cognitive vigilance and reaction time among soccer players significantly improved following administration of L-Tyrosine.

Results showed that in warm-weather conditions, L-Tyrosine could enhance cognitive function and prevent cognitive impairment during exposure to exercise-heat stress.[v]

  1. L-Tyrosine boosts neurotransmitters. L-Tyrosine taken as a supplement converts into the neurotransmitter dopamine. Dopamine helps control movement in your body, is fundamental to memory, attention and problem solving.

The unused dopamine can then convert into the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).

Norepinephrine is important for attentiveness, emotions, sleeping, dreaming and learning.

Epinephrine drives your ‘flight-or-flight’ response. It’s what prompts your reaction to dangerous circumstances, emergency situations, or in stressful situations or environments.

In one study done in the Netherlands, researchers determined if L-Tyrosine would boost cognitive resources associated with cognitive control. They performed tests designed to measure “working memory” using the N-Back Test.

Study participants were assigned to engage in a “1-back” condition of easy difficulty and then a 2-back condition of tougher difficulty. Those that used L-Tyrosine demonstrated superior performance in the 2-back test, but not the 1-back test.

The study authors suggested that L-Tyrosine provides greater cognitive enhancement when cognitive demand increases. The bottom-line; supplementation of L-Tyrosine may help you increase your IQ score due to maximizing catecholamine reserves.[vi]

How things go bad

As we get older, our brain and body chemistry and energy metabolism changes.

L-tyrosine side effects↓ Dopaminergic neurons are damaged or die

↓ Neurotransmitter levels decline

↓ Thyroid hormones decline

↑ Stress levels increase

↓ Working memory and mood decline

All of these changes are often attributed to aging. But could be a result of dietary and lifestyle choices.

Unchecked, they could lead to neurodegenerative diseases like Parkinson’s, a drop-in quality of life and depression.

L-Tyrosine benefits

L-Tyrosine can boost levels of the neurotransmitters dopamine, norepinephrine, and epinephrine. And contributes to the production of thyroid hormones T4 and T3.

Tyrosine can help boost cognition especially in stressful situations. It helps improve decision making, ‘flow state’ and creativity, cognitive flexibility, and working memory.

L-Tyrosine converts into L-DOPA to produce dopamine. L-DOPA is also used to make melanin in your body. This conversion process helps in the removal of neurotoxic quinones. And chelates heavy metals like mercury and lead which can accumulate in and damage neurons.

The dopamine that is not used by your brain is available to produce norepinephrine (noradrenaline) which is important for attentiveness, emotions, sleeping, dreaming, and learning.

L-Tyrosine can be an effective nootropic when stacked with ADHD/ADD meds like Ritalin or Adderall. It helps supply extracellular dopamine needed to improve the effectiveness of stimulants used to boost the uptake of dopamine in your brain.

How does L-Tyrosine as a nootropic feel?

Keep in mind that L-Tyrosine is a precursor to catecholamines. So if you’re not ‘low’ on dopamine, norepinephrine or epinephrine – you may not ‘feel’ anything.

L-tyrosine adhdMany neurohackers report a lift in mood, better focus, concentration, increased energy, and an overall sense of well-being. L-Tyrosine can help readjust your motivation levels. It can help lower anxiety levels, especially social anxiety.

Supplementing with L-Tyrosine can help bring your blood pressure down if its elevated from a stressful situation or environment. Take it before the stressful event if you can.

L-Tyrosine helps buffer the effects of stimulants like caffeine or amphetamines. It helps potentiate and prolong the effects of Ritalin or Adderall, and reduces the crash.

If you’re into athletics or do manual work, you’ll find that supplementing with L-Tyrosine before a workout or construction job will leave you feeling great afterwards. It helps mitigate many of the effects of acute stress caused by short-term stressors.

And L-Tyrosine helps your body to produce melanin, so you may find it easier to get a tan while at the beach.

l-tyrosine benefits

L-Tyrosine Research

L-Tyrosine to treat ADHD

Several studies have investigated using L-Tyrosine for the treatment of attention deficit hyperactivity disorder (ADHD). One informal study published in the 1980’s determined that L-Tyrosine resulted in short-term relief from ADHD symptoms. But subjects eventually reached tolerance and a diminished effect.

This is important for neurohackers to keep in mind. It seems that L-Tyrosine on its own can benefit some more than others. Regardless if you’re treating ADHD, or are perfectly cognitively healthy.

I’ve seen more than one report of nootropic users experiencing tolerance after just a week of supplementing with L-Tyrosine. But most peer-reviewed, published studies show positive results.

One study published in Neuropsychiatric Disease and Treatment in 2011 looked at using amino acid precursors for the treatment of deficit hyperactivity disorder (ADHD). Including L-Tyrosine for dopamine, and 5-HTP for serotonin.

The study used 85 young people aged 4 – 18 years old, all with a clinical diagnosis of ADHD. They were treated for an initial period of 8 – 10 weeks.

Urinary samples to determine serotonin and dopamine levels were collected within the first 4 weeks. If they didn’t reach adequate levels, subjects were moved to higher dosing levels 2 and then 3 until they got relief from symptoms.

Researchers found that the dopamine and serotonin precursors yielded similar results to Strattera and Ritalin. And “the amino acid protocol may be equal in efficacy to potent, pharmaceutical ADHD medications”.[vii]

L-Tyrosine reduces blood pressure under stress

This study is particularly interesting for its nootropic application. It’s commonly understood that blood pressure rises when we’re under stress. The source of stress doesn’t really matter. Stress up = blood pressure up.

A study in Amsterdam showed that L-Tyrosine administration decreased blood pressure about 15 minutes after ingestion. This study involved assessing task performance following acute stress.

Acute stress is usually short-term and can be caused by driving, fighting, athletics, martial arts training, war, combat training, CrossFit, cold showers, loud music, intense movies, loud noises, business deals, relationships, school, exams and more.

The point is, this study is applicable to every one of us. The study found that L-Tyrosine reduced diastolic blood pressure within 15 minutes of taking the supplement. And blood pressure normalized within 1 hour.

This study tells us that L-Tyrosine may promote a decrease in blood pressure caused by stress. And could be used to mitigate the effects of stressful situations if taken prior to the stressful event.[viii]

L-Tyrosine promotes cognitive flexibility

Cognitive flexibility applies to those who can adjust their thinking quickly to adapt to novel situations and stimuli. A high degree of cognitive flexibility is associated with increased fluid intelligence, superior reading and comprehension, and a healthier brain.

Recent research (2015) supports the idea that L-Tyrosine promotes cognitive flexibility. In this trial, researchers recruited 22 adults. And setup a double-blind, placebo-controlled study.

All subjects were assigned a task switching procedure to measure their flexibility. The results showed that receiving L-Tyrosine supplementation increased cognitive flexibility compared to the placebo group.

The researchers determined that “L-Tyrosine can facilitate cognitive flexibility by repleting cognitive resources”.[ix]

The team observed that increased cognitive flexibility was likely due to a boost in dopamine concentrations. They noted that L-Tyrosine enhanced usage of various cognitive resources. And one way to increase your cognitive flexibility would be to start supplementing with L-Tyrosine.

It stands to reason that people who are close-minded, set it their ways, are resistant to change and can’t cope with unexpected stimuli or situations have “cognitive rigidity”. And it’s likely due to suboptimal dopamine levels.

l tyrosine dosage child

L-Tyrosine Dosage

L-Tyrosine suggested dosage for cognitive benefit is 500 mg – 2 grams per day.

You may find your body responds to smaller doses. Or even more if you’re stacking it with stimulants like ADHD meds. Listen to your body and see how you react.

If you find you do not experience the full benefit from L-Tyrosine,  then try using it an hour before or two hours after a meal. Because L-Tyrosine taken as a supplement may compete with other amino acids in food for transport into your system.

I personally stack L-Tyrosine with my Ritalin dose twice per day. And a final dose of L-Tyrosine late afternoon to prevent a stimulant crash.

NOTE: long-term use of L-Tyrosine can suppress serotonin. Symptoms include depression, fatigue or severe anxiety feeling much like a panic attack. You can easily counter this by supporting serotonin with a 250 – 500 mg L-Tryptophan about 60 mins. before bed.

L-Tyrosine Side Effects

L-Tyrosine is considered non-toxic and very safe. Most neurohackers and healthy human adults don’t have any negative side effects from using amino acid tyrosine as a nootropic supplement.

At higher doses there are reports of stomach issues and migraines. Migraine problems usually happen to those who already suffer from migraines. This may be an indication that your neurotransmitter levels are already optimal, and you don’t need to supplement with L-Tyrosine.

L-Tyrosine can increase your thyroid hormones. So if you’re hyperthyroid you should use caution when supplementing with L-Tyrosine because it may change the way your thyroid meds work.

And if you’re taking MAO inhibitors (MAOI’s) like selegiline, Azilect, Marplan or Nardil you should not use L-Tyrosine.

Monoamine oxidase inhibitors (MAOIs) work in your brain by blocking the enzyme monoamine oxidase. This enzyme normally blocks excess dopamine. But when you block the enzyme, more dopamine is released.

So using L-Tyrosine in combination with MAOI’s could raise dopamine levels too high. Resulting in a rapid rise in blood pressure (hypertensive crisis). Causing severe headache, nausea and sweating, severe anxiety, rapid heartbeat, chest pain, vision changes, shortness of breath and confusion.

A severe increase in blood pressure from this combo can lead to hemorrhagic stroke or a heart attack.

Where to buy L-Tyrosine

L-Tyrosine is available to buy in powder, capsule and tablet form. Capsules and tablets are usually 300 – 500 mg.

Some pre-made nootropic stacks and workout stacks also include L-Tyrosine as part of their formula.

N-Acetyl L-Tyrosine (NALT) is an alternative to plain L-Tyrosine. NALT has an acetyl group added to L-Tyrosine in an attempt to make it more bioavailable.

For example, Mind Lab Pro® 4.0 contains 11 brain enhancing nootropic compounds including N-Acetyl L-Tyrosine.

I recommend Mind Lab Pro because it addresses all aspects of anxiety resistance, memory and cognitive enhancement, stabilizes mood, brain repair, and maintenance.

This premium nootropic stack is designed to affect neurotransmitters, cognitive energy, brain waves, neuroprotection, and regeneration. See my Mind Lab Pro review for a detailed report.

Ensure you read labels carefully and stick with manufacturers who follow Good Manufacturing Practices (GMP). And are GMP-Certified. And do your best to avoid toxic “other ingredients” which are usually listed at the bottom of “Supplement Facts” labels.

Nootropics Expert Recommendation

Nootropics Expert Tested and ApprovedL-Tyrosine 500 mg – 2 grams per day

I recommend using L-Tyrosine as a nootropic supplement.

Your body does synthesize some L-Tyrosine from phenylalanine which comes from high-protein foods like chicken, fish, almonds, avocados and bananas.

But most of us don’t get enough L-Tyrosine from our diet. So supplementation will help.

L-Tyrosine is helpful for most neurohackers to combat stress and sleep deprivation. It’ll boost dopamine, norepinephrine and epinephrine levels.

It’s particularly helpful if you take L-Tyrosine prior to a stressful situation, workout or physically demanding job.

L-Tyrosine is especially helpful to those dealing with ADHD/ADD. It’s a great compliment to stack with stimulant meds like Ritalin or Adderall. L-Tyrosine will provide the dopamine your brain needs. It will help smooth out and prolong the effects of stimulant meds. And help prevent the associated crash when they wear off.

A good stack for ADHD is using your usual med dose with L-Tyrosine 500 mg, Alpha GPC 300 mg, and ALCAR 500 mg. Which is should particularly effective if you are dealing with any phenylalanine abnormalities.

You can buy individual L-Tyrosine supplements. Or you could try my favorite pre-formulated nootropic stack Mind Lab Pro® 4.0 which includes N-Acetyl L-Tyrosine (NALT).

Mind Lab Pro contains a synergistic blend of 11 brain enhancing nootropics covering all aspects of cognition and brain health. See my full Mind Lab Pro review for more.

You can safely use up to 2,000 mg per day when stacking with ADHD meds. But in smaller divided doses throughout your day.

As an Amazon Associate I earn from qualifying purchases. This post may also contain other affiliate links and I will be compensated if you make a purchase after clicking on my links.

[i] Slominski A., Zmijewski M., Pawelek J. “L-tyrosine and L-DOPA as hormone-like regulators of melanocytes functions” Pigment Cell Melanoma Research. 2012 Jan; 25(1): 14–27. (source)

[ii] Woods S.K., Meyer J.S. “Exogenous tyrosine potentiates the methylphenidate-induced increase in extracellular dopamine in the nucleus accumbens: a microdialysis study.” Brain Research. 1991 Sep 27;560(1-2):97-105. (source)

[iii] Hase A., Jung S.E., aan het Rot M. “Behavioral and cognitive effects of tyrosine intake in healthy human adults.” Pharmacology, Biochemistry and Behavior. 2015 Jun;133:1-6. (source)

[iv] Magnusson I., Ekman L., Wångdahl M., Wahren J. “N-acetyl-L-tyrosine and N-acetyl-L-cysteine as tyrosine and cysteine precursors during intravenous infusion in humans.” Metabolism. 1989 Oct;38(10):957-61. (source)

[v] Coull N.A., Watkins S.L., Aldous J.W., Warren L.K., Chrismas B.C., Dascombe B., Mauger A.R., Abt G., Taylor L. “Effect of tyrosine ingestion on cognitive and physical performance utilising an intermittent soccer performance test (iSPT) in a warm environment.” European Journal of Applied Physiology. 2015 Feb;115(2):373-86. (source)

[vi] Colzato L.S., Jongkees B.J., Sellaro R., Hommel B. “Working memory reloaded: tyrosine repletes updating in the N-back task.” Frontiers in Behavioral Neuroscience. 2013 Dec 16;7:200. (source)

[vii] Hinz M., Stein A., Neff R., Weinberg R., Uncini T. “Treatment of attention deficit hyperactivity disorder with monoamine amino acid precursors and organic cation transporter assay interpretation” Neuropsychiatric Disease and Treatment. 2011; 7: 31–38. (source)

[viii] Deijen J.B., Orlebeke J.F. “Effect of tyrosine on cognitive function and blood pressure under stress.” Brain Research Bulletin. 1994;33(3):319-23. (source)

[ix] Steenbergen L., Sellaro R., Hommel B., Colzato L.S. “Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance.” Neuropsychologia. 2015 Mar;69:50-5 (source)

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Join The Discussion - 375 comments

Paolo
December 3, 2020

Hi David,
is it true daylie masturbation can lead to a dopamine deficiency ?
Does the same would apply for sex ?
What would be a safe interval of masturbation to pretend deficiency ?
Does sleep orgasm (wet dreams) aswell can cause dopamine deficiency ?

For gaming,
is it true gaming can cause dopamine deficiency ?
How much hours per day are safe, or days per week ?

Could you tell me other activities which can cause deficiency and or list them together with mentioned above with priority ?

Thanks.

Dinah
November 19, 2020

Hi,

This is a very informative article, thank you.
I suffer from atypical depression, anxiety, I have low absorption of vitamin D and sometimes levels close to hypothyroidism but it fluctuates within normal values. I’m not on any medication. I take a vitamin D supplement.
I have taken Ltyrosine as part of a B vitamin complex (ergystress is the brand) for about 5 months and then a standalone ltyrosine supplement (500mg from Solgar) once a day for about two months. It made me feel amazing for a while, I felt like a whole new person, and this was all during pandemic, so all the more appreciated and surprising. Then the effects started to fade, but I still felt grounded and energetic enough to go through most days. I stopped taking it about two weeks ago, mostly because I read one shouldn’t supplement for longer than 3 months and I fell in deep depression, one of the worst spells I’ve had. I feel panicky, brain fog, social anxiety, unable to make decisions or communicate properly.
I was reading this bit from your article:
NOTE: long-term use of L-Tyrosine can suppress serotonin. Symptoms include depression, fatigue or severe anxiety feeling much like a panic attack. You can easily counter this by supporting serotonin with a low dose of 5-HTP (i.e. 25 – 50 mg).

Could you please expand on this? Is my serotonin suppressed because I supplemented with l-tyrosine for too long? Would it help if I took 5htp?
Please help, any advice is welcome, I am at the deep end of this.

    David Tomen
    November 19, 2020

    Dinah, that’s is very likely what happened because serotonin and dopamine must be in balance. You can use L-Tyrosine daily for the rest of your life as long as you also support serotonin. But I need to change my 5-HTP recommendation. Please use L-Tryptophan instead. L-Tyrosine during the day and 250 – 500 mg L-Tryptophan about 60 mins. before bed.

      Dinah
      November 20, 2020

      Thank you so much, I’ll give it a try! Happy to know i can continue Ltyrosine!

Mohamed
November 12, 2020

Does NALT raise thyroid hormones and blood pressure in a normal person, who wish to benefit it as a boost for essential neurotransmitters dopamine, EN NEN.

    David Tomen
    November 13, 2020

    Mohamed, tyrosine is one of the things that makes thyroid hormone. Along with selenium, iodine, magnesium and Vitamin C. If you did not have tyrosine in your system you could not make thyroid hormones.

    And it will not raise blood pressure if you are a normal, healthy guy.

Damian
November 11, 2020

Hello David, can i take L Tyrosine in the recomended doses for months without the problem of supresses Seratonin Levels? and the other Question is,
How will I know when it is time to consume L Tryptofan if i needed for increase Seratonine? The imbalance is only caused by these two substances, L tyrosine and L Tryptofan, or it can also be caused by a high consumption of any precursor of either of the two, such as CBD oil for a long time?

    David Tomen
    November 14, 2020

    Damian, good question and there is no real answer to it because it depends. If your dose of L-Tyrosine is low enough you may not need to use L-Tryptophan. But if you find yourself feeling on edge and kinda’ ‘antsy’ then you’ll know you need to add L-Tryptophan.

    The only other precursor to serotonin is 5-HTP which I don’t suggest trying. And for dopamine the other precursors are Phenylalanine and L-DOPA.

      Damian
      November 16, 2020

      Thank you for your generosity in answering all my questions, you are a great man, I wish you could convince Performance Lab NutriGenesis® to sell on Amazon to be able to acquire their products since I am from Uruguay and Amazon is the most accessible medium due to customs in my country, I send you a big greeting

        David Tomen
        November 17, 2020

        Thank you Damian. It’s highly unlikely that Performance Lab will ever be offered on Amazon. I’ve know them for years and their commitment to quality is almost a religion to them. It’s why during COVID they sometimes run out of stock on a supplement. It’s because they can’t get one ingredient. And they refuse to replace the missing ingredient with something of lesser quality.

        It’s that commitment to quality that keeps them from entering a marketplace with competitors who sell lower quality products. And avoiding a less than honest review process that is easily manipulated by those competitors.

Pris
September 29, 2020

Hello David.

I know that caffeine tends to just “push us” and “borrow” energy from the future (often leaving us more tired), but is Tyrosine in the same boat? Does it just help us push through too, our does it give our bodies something so they can function better? Is there a “crash” associated with it?

    David Tomen
    September 29, 2020

    Pris, L-Tyrosine is a natural precursor to the synthesis of dopamine. You get it from food or a supplement.

    If you follow dosage recommendations you’ll get the benefit of more dopamine and there is no crash. But it helps to keep a constant level in your system which is the reason why we use L-Tyrosine 2 or 3-times per day.

Hakan
September 4, 2020

Hi David,

It is told by many researches that the dosage should be 100/150 mg per kg to see the mental effect Benefits.
You recommend 500 to 2000 mg per day. Why it differs?

Thanks

    David Tomen
    September 4, 2020

    Hakan, because following that advice if you’re 90 kg then the minimum dose you’d use per day would be 9 grams of L-Tyrosine. Which is an insane amount of L-Tyrosine to use. Unless you wanted a really unpleasant experience.

Tiago
July 3, 2020

Should I take it before or along with vyvanse?

    David Tomen
    July 4, 2020

    Tiago, take it with Vyvanse so the drug has enough dopamine available to provide the intended benefit of Vyvanse.

    See my post on what else you can do to support prescription stimulants for treating ADD/ADHD here: https://nootropicsexpert.com/best-nootropics-for-adhd-add/

      Tiago
      July 6, 2020

      But it would be better take it before or at the same time as vyvanse?

        David Tomen
        July 7, 2020

        Tiago, good question but you can take them as the same time. Both are very bioavailable and begin to work within 10 – 15 mins.

    Beau
    September 12, 2020

    Would cycling (5 days on, 2 days off for example)Tyrosine help to prevent building up tolerance if you want to avoid medication?

      David Tomen
      September 14, 2020

      Beau, if you use recommended dosages for L-Tyrosine there should be no need to cycle. Tolerance with something as benign as an amino acid like tyrosine comes from long-term use at higher than normal dosages.

Shane Roberts
June 17, 2020

Hi David,

Pleasure to be able to speak with an experienced professional in nootropics.

I’ve been studying, experimenting, and supplementing nootropics for a couple years now. I’ve learned extensive material from many of your YouTube videos and I guess I’ve never been able to figure out these two things.

1) “Perfect Synergy” How to prevent serotonin syndrome or other negative interactions whilst supplementing several different chemicals at once, given the knowledge of which neurotransmitter the supplement boosts, depletes, suppresses, blocks etc (or if the chemical is serotonergic/dopaminergic…; or an antagonist to a certain neurotransmitter).
For example, what terms (ex: re-uptake, inhibits, boosts/depletes) are most crucial in determining a possible negative interaction between these supplements: L-Tyrosine, Rhodiola Root, ALCAR, ALA, Adderall, 5-HTP, Caffeine, Vinpocetine, and Garcinia Cambogia.

2) What Supplements would you recommend for a 25-30 year old single male who is extremely busy with work and struggles with stress and depression from anxiety, OCD, and lack of social life/finding a relationship.

I usually find myself trying to improve/“perfect” my apartment or car with all of my free time and waste too much time due to OCD and anxiety.

    David Tomen
    June 17, 2020

    Shane, the nootropics you listed should work well together as long as you follow recommended dosages. You should add a couple more if you’re supporting Adderall use. See my post on nootropics for ADHD here: https://nootropicsexpert.com/best-nootropics-for-adhd-add/

    I’ve done the research and have posts on social anxiety and depression which you can easily find by using the search function top right.

    If you need more help consider scheduling a consultation with me and we can have things sorted out in an hour: https://nootropicsexpert.com/personal-consultations/

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